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The map label for this gene is fadH [H]

Identifier: 77459909

GI number: 77459909

Start: 4171309

End: 4173348

Strand: Reverse

Name: fadH [H]

Synonym: Pfl01_3687

Alternate gene names: 77459909

Gene position: 4173348-4171309 (Counterclockwise)

Preceding gene: 77459912

Following gene: 77459908

Centisome position: 64.82

GC content: 62.65

Gene sequence:

>2040_bases
ATGACCGCCACTCAATACCCGCACCTGTTGGCCCCGCTGGACCTGGGATTCACCACGTTGCGCAACCGCACCCTGATGGG
GTCGATGCACACTGGCCTTGAAGAGAAACCGGGCGGTTTCGAACGCATGGCGGCGTATTTCGCCGAGCGTGCCCGTGGCG
GCGTTGGCCTGATGGTCACCGGCGGTATCGGTCCGAATGACGAGGGCGGTGTGTATTCCGGCGCGGCCAAGCTGACCACC
GAGGAAGAAGCGCTCCAACACCGCATCGTCACGCGCGCCGTGCACGAGGCGGGCGGCAAGATCTGCATGCAGATCCTCCA
CGCCGGCCGTTATGCCTACAGTCCGAAACAGGTCGCGCCGAGCGCCATTCAGGCGCCGATCAACCCGTTCAAGCCCAAAG
AGCTGGACGAGGAAGGCATCGAGAAGCAGATCCGCGATTTCGTCACCTGCTCGGTACTGGCCCAGACCGCCGAGTACGAC
GGCGTGGAAATCATGGGCTCGGAAGGTTATTTCATTAACCAGTTCCTCGCCGCCCACACCAACCACCGCACCGACCGTTG
GGGCGGCAGCTACGAAAACCGCATGCGCCTGCCGGTGGAGATCGTTCGCCGGGTGCGTGAAGCGGTGGGCCCGAACTTCA
TCATCATCTTCCGTCTGTCGATGCTCGATCTGGTGGAAGGTGGCAGCACCTGGGAAGAAATCGTCACCCTGGCCAAAGCC
ATCGAGCAGGCCGGCGCGACCCTCATCAACACCGGCATCGGCTGGCACGAAGCGCGGATCCCGACCATCGCCACCAAAGT
GCCGCGTGCGGCGTTCAGCAAGGTCACGGCCAAGCTGCGCGGTTCGGTGAATATTCCGCTGATCACCACCAACCGCATCA
ACACCCCGGAAATCGCCGAGCAGATCCTCGCTGAAGGCGATGCCGACATGGTCTCGATGGCGCGGCCGTTCCTCGCCGAC
CCGGATTTCGTCAACAAGGCCGCCGAAGGTCGCGCCGACGAAATCAATACCTGCATCGGCTGCAACCAGGCCTGCCTCGA
TCACACCTTCGGCGGCAAGCTCACCAGCTGCCTGGTCAACCCGCGTGCCTGCCACGAAACCGAACTCAACTACCTGCCGG
TCAAGCAGATCAAGAAAATCGCCGTGGTCGGTGCCGGTCCTGCCGGTCTGTCCGCCGCCACCGTGGCCGCCGAGCGCGGG
CATCAGGTGACCTTGTTCGATTCGGCCAGCGAGATCGGTGGCCAGTTCAATGTCGCCAAGCGAGTGCCGGGCAAGGAAGA
GTTCTACGAAACCCTGCGTTACTTCAAACGCAAGTTGCAGACCACCAACGTTGAGGTGTGTCTGAACACCCGCGTCGATG
TGGCAAAACTGGTCGAGGGCGGTTACGACGAAGTCATCCTCGCGACCGGCATTGCACCGCGTCTTCCGGCGATTCCGGGC
GTCGAAAACGCCAAAGTGCTGAGCTACCTTGATGTGCTGCTCGAGCGCAAACTGGTCGGCAAGCGTGTAGCGGTGATCGG
CGCCGGCGGTATCGGTTTCGACGTGTCGGAATTCCTCGTCCATGAAGGCGTGGCCACCAGTCAGGATCGCGCTGCGTTCT
GGAAAGAGTGGGGGATCGACACGAATCTGGAAGCCCGTGGTGGCGTGGCCGGGATCAAAGCTGCACCGCACGCACCAGCG
CGCGACGTGTTCCTGCTGCAACGCAAGAAATCCAAGGTCGGCGACGGCTTGGGCAAGACCACCGGCTGGATTCACCGCAC
CGGTTTGAAGAACAAGCAGGTGCAGATGCTCAACAGCGTCGAATACCTGAAGATCGACGACGAAGGCCTGCACATCCGCA
TCGGCGAAACCGGCGAACCGCAAGTGCTGCCGGTGGACAACATCGTCATTTGCGCCGGCCAGGATCCGCTGCGCGAGCTG
CACGACGGTCTGGTCGAAGCCGGGCAGAACGTGCACCTGATCGGCGGCGCCGATGTGGCGGCCGAGCTGGATGCCAAACG
TGCGATCAATCAGGGTTCGCGTCTGGCCGCCGAGCTCTGA

Upstream 100 bases:

>100_bases
TCATTGAGTGACAGCGAGGCGACTCCTAATCTGTCGAGCATGACTGACGGGGGACGCAGAGCTCCCGCATTTTCCGTGAT
CGCTCGCTGTGGAGTTAACG

Downstream 100 bases:

>100_bases
TCCACCCTAGAATGCCGGCTCTTTGCACAGAGCCGGCCTTCATGTTTCTGCCTCCCACCGACTGGCTACCTCAAGCCCCC
CTCGAAGCGCTTCATCTGGA

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MTATQYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPGGFERMAAYFAERARGGVGLMVTGGIGPNDEGGVYSGAAKLTT
EEEALQHRIVTRAVHEAGGKICMQILHAGRYAYSPKQVAPSAIQAPINPFKPKELDEEGIEKQIRDFVTCSVLAQTAEYD
GVEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIFRLSMLDLVEGGSTWEEIVTLAKA
IEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVNIPLITTNRINTPEIAEQILAEGDADMVSMARPFLAD
PDFVNKAAEGRADEINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPVKQIKKIAVVGAGPAGLSAATVAAERG
HQVTLFDSASEIGGQFNVAKRVPGKEEFYETLRYFKRKLQTTNVEVCLNTRVDVAKLVEGGYDEVILATGIAPRLPAIPG
VENAKVLSYLDVLLERKLVGKRVAVIGAGGIGFDVSEFLVHEGVATSQDRAAFWKEWGIDTNLEARGGVAGIKAAPHAPA
RDVFLLQRKKSKVGDGLGKTTGWIHRTGLKNKQVQMLNSVEYLKIDDEGLHIRIGETGEPQVLPVDNIVICAGQDPLREL
HDGLVEAGQNVHLIGGADVAAELDAKRAINQGSRLAAEL

Sequences:

>Translated_679_residues
MTATQYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPGGFERMAAYFAERARGGVGLMVTGGIGPNDEGGVYSGAAKLTT
EEEALQHRIVTRAVHEAGGKICMQILHAGRYAYSPKQVAPSAIQAPINPFKPKELDEEGIEKQIRDFVTCSVLAQTAEYD
GVEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIFRLSMLDLVEGGSTWEEIVTLAKA
IEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVNIPLITTNRINTPEIAEQILAEGDADMVSMARPFLAD
PDFVNKAAEGRADEINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPVKQIKKIAVVGAGPAGLSAATVAAERG
HQVTLFDSASEIGGQFNVAKRVPGKEEFYETLRYFKRKLQTTNVEVCLNTRVDVAKLVEGGYDEVILATGIAPRLPAIPG
VENAKVLSYLDVLLERKLVGKRVAVIGAGGIGFDVSEFLVHEGVATSQDRAAFWKEWGIDTNLEARGGVAGIKAAPHAPA
RDVFLLQRKKSKVGDGLGKTTGWIHRTGLKNKQVQMLNSVEYLKIDDEGLHIRIGETGEPQVLPVDNIVICAGQDPLREL
HDGLVEAGQNVHLIGGADVAAELDAKRAINQGSRLAAEL
>Mature_678_residues
TATQYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPGGFERMAAYFAERARGGVGLMVTGGIGPNDEGGVYSGAAKLTTE
EEALQHRIVTRAVHEAGGKICMQILHAGRYAYSPKQVAPSAIQAPINPFKPKELDEEGIEKQIRDFVTCSVLAQTAEYDG
VEIMGSEGYFINQFLAAHTNHRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIFRLSMLDLVEGGSTWEEIVTLAKAI
EQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVNIPLITTNRINTPEIAEQILAEGDADMVSMARPFLADP
DFVNKAAEGRADEINTCIGCNQACLDHTFGGKLTSCLVNPRACHETELNYLPVKQIKKIAVVGAGPAGLSAATVAAERGH
QVTLFDSASEIGGQFNVAKRVPGKEEFYETLRYFKRKLQTTNVEVCLNTRVDVAKLVEGGYDEVILATGIAPRLPAIPGV
ENAKVLSYLDVLLERKLVGKRVAVIGAGGIGFDVSEFLVHEGVATSQDRAAFWKEWGIDTNLEARGGVAGIKAAPHAPAR
DVFLLQRKKSKVGDGLGKTTGWIHRTGLKNKQVQMLNSVEYLKIDDEGLHIRIGETGEPQVLPVDNIVICAGQDPLRELH
DGLVEAGQNVHLIGGADVAAELDAKRAINQGSRLAAEL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=676, Percent_Identity=62.7218934911243, Blast_Score=854, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=342, Percent_Identity=29.5321637426901, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=298, Percent_Identity=25.8389261744966, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=301, Percent_Identity=25.2491694352159, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=301, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=302, Percent_Identity=25.1655629139073, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=320, Percent_Identity=24.375, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=327, Percent_Identity=26.605504587156, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=204, Percent_Identity=26.9607843137255, Blast_Score=80, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321973, Length=352, Percent_Identity=24.7159090909091, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=223, Percent_Identity=27.3542600896861, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73454; Mature: 73323

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATQYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPGGFERMAAYFAERARGGVGLMVT
CCCCCCCCHHCHHHCCHHHHHCCCEECHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEE
GGIGPNDEGGVYSGAAKLTTEEEALQHRIVTRAVHEAGGKICMQILHAGRYAYSPKQVAP
CCCCCCCCCCEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
SAIQAPINPFKPKELDEEGIEKQIRDFVTCSVLAQTAEYDGVEIMGSEGYFINQFLAAHT
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
NHRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIFRLSMLDLVEGGSTWEEIVTLAKA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHH
IEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVNIPLITTNRINTPEIAE
HHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
QILAEGDADMVSMARPFLADPDFVNKAAEGRADEINTCIGCNQACLDHTFGGKLTSCLVN
HHHHCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHCC
PRACHETELNYLPVKQIKKIAVVGAGPAGLSAATVAAERGHQVTLFDSASEIGGQFNVAK
CCCCCCCCCCCCCHHHHCEEEEEECCCCCCHHHHHHHHCCCEEEEECCHHHCCCCEEHHH
RVPGKEEFYETLRYFKRKLQTTNVEVCLNTRVDVAKLVEGGYDEVILATGIAPRLPAIPG
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEEEECCCCCCCCCCCC
VENAKVLSYLDVLLERKLVGKRVAVIGAGGIGFDVSEFLVHEGVATSQDRAAFWKEWGID
CCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCC
TNLEARGGVAGIKAAPHAPARDVFLLQRKKSKVGDGLGKTTGWIHRTGLKNKQVQMLNSV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHCCC
EYLKIDDEGLHIRIGETGEPQVLPVDNIVICAGQDPLRELHDGLVEAGQNVHLIGGADVA
EEEEECCCCEEEEECCCCCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHH
AELDAKRAINQGSRLAAEL
HHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
TATQYPHLLAPLDLGFTTLRNRTLMGSMHTGLEEKPGGFERMAAYFAERARGGVGLMVT
CCCCCCCHHCHHHCCHHHHHCCCEECHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEE
GGIGPNDEGGVYSGAAKLTTEEEALQHRIVTRAVHEAGGKICMQILHAGRYAYSPKQVAP
CCCCCCCCCCEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
SAIQAPINPFKPKELDEEGIEKQIRDFVTCSVLAQTAEYDGVEIMGSEGYFINQFLAAHT
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHC
NHRTDRWGGSYENRMRLPVEIVRRVREAVGPNFIIIFRLSMLDLVEGGSTWEEIVTLAKA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHH
IEQAGATLINTGIGWHEARIPTIATKVPRAAFSKVTAKLRGSVNIPLITTNRINTPEIAE
HHHCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
QILAEGDADMVSMARPFLADPDFVNKAAEGRADEINTCIGCNQACLDHTFGGKLTSCLVN
HHHHCCCCHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHCC
PRACHETELNYLPVKQIKKIAVVGAGPAGLSAATVAAERGHQVTLFDSASEIGGQFNVAK
CCCCCCCCCCCCCHHHHCEEEEEECCCCCCHHHHHHHHCCCEEEEECCHHHCCCCEEHHH
RVPGKEEFYETLRYFKRKLQTTNVEVCLNTRVDVAKLVEGGYDEVILATGIAPRLPAIPG
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEEEECCCCCCCCCCCC
VENAKVLSYLDVLLERKLVGKRVAVIGAGGIGFDVSEFLVHEGVATSQDRAAFWKEWGID
CCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCC
TNLEARGGVAGIKAAPHAPARDVFLLQRKKSKVGDGLGKTTGWIHRTGLKNKQVQMLNSV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHCCC
EYLKIDDEGLHIRIGETGEPQVLPVDNIVICAGQDPLRELHDGLVEAGQNVHLIGGADVA
EEEEECCCCEEEEECCCCCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHH
AELDAKRAINQGSRLAAEL
HHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]