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The map label for this gene is cueR [H]

Identifier: 77459875

GI number: 77459875

Start: 4134482

End: 4134883

Strand: Direct

Name: cueR [H]

Synonym: Pfl01_3653

Alternate gene names: 77459875

Gene position: 4134482-4134883 (Clockwise)

Preceding gene: 77459874

Following gene: 77459876

Centisome position: 64.22

GC content: 59.2

Gene sequence:

>402_bases
ATGAGCAGCCAGACCTACAGCATTTCCGACCTCGCCCGCGAGCTGGACATCACCACCCGGGCGATCCGCTTCTATGAAGA
ACAAGGCCTGCTCAGCCCCGAGCGCCGAGGCCAGGAACGCATCTATTCGCCACGCGACAAGGTCAGCCTGAAGCTGATCC
TGCGGGGCAAGCGCATCGGTTTTTCCCTGGCCGAGTGCCGTGAACTGATCGAGCTCTACGACCCCTCCAGCGGTAACACC
AAACAACTCAACAGCATGCTGGCGAAAATCAGCGAGCGCCGGGCACAGCTTGAACAGCAACTGCTGGACATCGAACAGAT
GAAGCTGGAACTCGACACCGCCGAAGAACGCTGCGTGCAGGCGCTGGAGCAGACGCTCAAGAGTCAGCAATCAGTTCAGT
AA

Upstream 100 bases:

>100_bases
GCCCACGAGAAGAAGCTCGACAAGCTGCAGGCGCCCGCCACTTGACGTAAACGTCAACCTGCCATTAGCTTAGCGCCAAG
ACCCTTCTTCGAGCGCTTTC

Downstream 100 bases:

>100_bases
CCTAAATAAATCCCACACGGGGTTCCGCAGGAATTCAAAGAGCAGGTCAACACCATGTCCCTCCCCTCCCAAGTACGCCT
GATCGAAGTCGGCCCGCGTG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MSSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPRDKVSLKLILRGKRIGFSLAECRELIELYDPSSGNT
KQLNSMLAKISERRAQLEQQLLDIEQMKLELDTAEERCVQALEQTLKSQQSVQ

Sequences:

>Translated_133_residues
MSSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPRDKVSLKLILRGKRIGFSLAECRELIELYDPSSGNT
KQLNSMLAKISERRAQLEQQLLDIEQMKLELDTAEERCVQALEQTLKSQQSVQ
>Mature_132_residues
SSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPRDKVSLKLILRGKRIGFSLAECRELIELYDPSSGNTK
QLNSMLAKISERRAQLEQQLLDIEQMKLELDTAEERCVQALEQTLKSQQSVQ

Specific function: Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15380; Mature: 15249

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPRDKVSLKLILRGKRIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHCCCCCHHHHHHHEEECCCCC
FSLAECRELIELYDPSSGNTKQLNSMLAKISERRAQLEQQLLDIEQMKLELDTAEERCVQ
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQTLKSQQSVQ
HHHHHHHHHHCCC
>Mature Secondary Structure 
SSQTYSISDLARELDITTRAIRFYEEQGLLSPERRGQERIYSPRDKVSLKLILRGKRIG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHCCCCCHHHHHHHEEECCCCC
FSLAECRELIELYDPSSGNTKQLNSMLAKISERRAQLEQQLLDIEQMKLELDTAEERCVQ
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQTLKSQQSVQ
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]