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The map label for this gene is nahR [H]

Identifier: 77459874

GI number: 77459874

Start: 4133482

End: 4134426

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_3652

Alternate gene names: 77459874

Gene position: 4133482-4134426 (Clockwise)

Preceding gene: 77459872

Following gene: 77459875

Centisome position: 64.2

GC content: 60.42

Gene sequence:

>945_bases
ATGAATCTGAGCAAGGTCGACCTCAACCTTTTCATCGTCTTCGACGCGATCTATACCGAAGCCAACCTGACACGCGCCGG
GCAGATTGTCGGCATTACCCAGCCTGCGGTGTCCAACGCATTGGCGCGGTTGCGCGAGACCTTCAACGACCCGCTCTTCG
TCCGCACCGCTCAGGGCATGGTGCCGACGCCCATGGCGCAGAACATCATCGGTCCGGTGCGCAACGCGCTGTCGCTGCTG
CGGGTGTCGGTTCAGGAAAGCCGCATTTTCAACCCTTCGCAAGCGGTCAAGACCTACCGCATCAGCATGACTGACCTGAC
CGAAGCGGTGATTCTGCCGCCGCTGTTCCAGCGTCTGCGTCGTCTGGCGCCGACTGTGATCATCGAAAGCTTTCTGTCCA
AACGCCGGGAAACCACCAAGGAGCTGGCTGCCGGGCGTCTCGACTTTGCCGTGGATGCGCCGCTCAACACCGACCCGCAG
GTGCGCCACGTCAAGCTGATGGAAGACCGTTACGTCTGCGCGATGCGCAAGGGTCATCCGCTGGCGACCAAGGAAAAATT
CACCCTCGACGATTACCTGTCGCTGACCCACATTCATATTTCCAGCCGGCGCAGTGGTCTGGGCCATGTCGATCTGGCGC
TGGGCAAAATGGGCATCCAGCGCAAGATCGCCCTGCGCTCGCAGCACTATTTGATGGCGTCTCAGGTGTTGCAGCAGACT
GATATGGTAATGACCGTGCCGGAGCGCTTCGCCCGTCGGCATGACCTGCATGCGTTCAATCTGCCGGTCAACGATGTGCC
GCCGGTGGAAACCCATTTGTACTGGCACGAAAGCACCGATCAGGACCCGGCCAACCGCTGGATGCGCGAGCAGATGATCG
AGTTGTGCCAGCAAGTGACAGCCCACGAGAAGAAGCTCGACAAGCTGCAGGCGCCCGCCACTTGA

Upstream 100 bases:

>100_bases
TATAAACATTCATCACCGATATATGATCGGTTGATTTTCCTGGCCGCCCTGACCCGCGCCATCCATCTATAACAAGCACC
TATAACAAGAGAGCCGCGTA

Downstream 100 bases:

>100_bases
CGTAAACGTCAACCTGCCATTAGCTTAGCGCCAAGACCCTTCTTCGAGCGCTTTCATGAGCAGCCAGACCTACAGCATTT
CCGACCTCGCCCGCGAGCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPSQAVKTYRISMTDLTEAVILPPLFQRLRRLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCAMRKGHPLATKEKFTLDDYLSLTHIHISSRRSGLGHVDLALGKMGIQRKIALRSQHYLMASQVLQQT
DMVMTVPERFARRHDLHAFNLPVNDVPPVETHLYWHESTDQDPANRWMREQMIELCQQVTAHEKKLDKLQAPAT

Sequences:

>Translated_314_residues
MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPSQAVKTYRISMTDLTEAVILPPLFQRLRRLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCAMRKGHPLATKEKFTLDDYLSLTHIHISSRRSGLGHVDLALGKMGIQRKIALRSQHYLMASQVLQQT
DMVMTVPERFARRHDLHAFNLPVNDVPPVETHLYWHESTDQDPANRWMREQMIELCQQVTAHEKKLDKLQAPAT
>Mature_314_residues
MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGMVPTPMAQNIIGPVRNALSLL
RVSVQESRIFNPSQAVKTYRISMTDLTEAVILPPLFQRLRRLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQ
VRHVKLMEDRYVCAMRKGHPLATKEKFTLDDYLSLTHIHISSRRSGLGHVDLALGKMGIQRKIALRSQHYLMASQVLQQT
DMVMTVPERFARRHDLHAFNLPVNDVPPVETHLYWHESTDQDPANRWMREQMIELCQQVTAHEKKLDKLQAPAT

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=29.7658862876254, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081766, Length=287, Percent_Identity=22.6480836236934, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786820, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789204, Length=204, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35693; Mature: 35693

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGM
CCCCEEEEEEEEEEEHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCC
VPTPMAQNIIGPVRNALSLLRVSVQESRIFNPSQAVKTYRISMTDLTEAVILPPLFQRLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHH
RLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRHVKLMEDRYVCAMRKGHP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHCHHHEECCCCCC
LATKEKFTLDDYLSLTHIHISSRRSGLGHVDLALGKMGIQRKIALRSQHYLMASQVLQQT
CCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
DMVMTVPERFARRHDLHAFNLPVNDVPPVETHLYWHESTDQDPANRWMREQMIELCQQVT
CCEEECHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AHEKKLDKLQAPAT
HHHHHHHHHCCCCC
>Mature Secondary Structure
MNLSKVDLNLFIVFDAIYTEANLTRAGQIVGITQPAVSNALARLRETFNDPLFVRTAQGM
CCCCEEEEEEEEEEEHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCC
VPTPMAQNIIGPVRNALSLLRVSVQESRIFNPSQAVKTYRISMTDLTEAVILPPLFQRLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHH
RLAPTVIIESFLSKRRETTKELAAGRLDFAVDAPLNTDPQVRHVKLMEDRYVCAMRKGHP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEHHCHHHEECCCCCC
LATKEKFTLDDYLSLTHIHISSRRSGLGHVDLALGKMGIQRKIALRSQHYLMASQVLQQT
CCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
DMVMTVPERFARRHDLHAFNLPVNDVPPVETHLYWHESTDQDPANRWMREQMIELCQQVT
CCEEECHHHHHHHCCCEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AHEKKLDKLQAPAT
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]