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The map label for this gene is glnS [H]

Identifier: 77459861

GI number: 77459861

Start: 4114878

End: 4116578

Strand: Reverse

Name: glnS [H]

Synonym: Pfl01_3639

Alternate gene names: 77459861

Gene position: 4116578-4114878 (Counterclockwise)

Preceding gene: 77459864

Following gene: 77459860

Centisome position: 63.94

GC content: 62.08

Gene sequence:

>1701_bases
ATGAGCAAGCCCACTGTCGACCCTACCTCGAATTCCAAGACCGGCCCCGTTACGCCGGTCAATTTCCTGCGCCCGATCAT
CCAGGCGGACCTGGACTCGGGTAAGCACACGCAGATCGTCACCCGTTTCCCGCCAGAGCCCAACGGCTACCTGCACATCG
GCCACGCCAAGTCGATCTGTGTGAACTTCGGCCTGGCCCAGGAGTTCGGCGGCGTCACTCACCTGCGTTTCGACGACACC
AACCCGGCCAAGGAAGACCAGGAATACATCGACGCGATCGAAAGCGACGTCAAATGGCTGGGCTTCGAATGGTCCGGCGA
AGTACGCTACGCCTCGCAATACTTCGACCAGCTGCACGACTGGGCCGTCGAGCTGATCAAGGCCGGCAAGGCCTACGTCG
ACGACCTGACGCCTGAGCAAGCCAAGGAATACCGCGGCAGCCTGACCGAGCCGGGCAAGAACAGCCCGTTCCGCGACCGG
TCGGTGGAAGAGAACCTGGACTGGTTCGCCCGCATGCGCGCCGGCGAGTTCCCGGACGGTGCCCGCGTACTGCGTGCCAA
GATCGACATGGCCTCGCCGAACATGAACCTGCGCGACCCGATCATGTACCGCATCCGCCACGCTCATCACCACCAGACCG
GTGACAAGTGGTGCATCTACCCGAACTACGACTTCACCCACGGTCAGTCGGACGCCATCGAAGGCATCACCCACTCGATC
TGCACCCTGGAGTTCGAAAGCCATCGTCCGCTGTACGAGTGGTTTCTCGACGCACTGCCAGTGCCGGCGCGTCCGCGTCA
GTACGAGTTCAGCCGCCTGAACCTCAACTACACCATCACCAGCAAGCGCAAGCTCAAGCAACTGGTTGACGAGAAACACG
TCAACGGCTGGGACGATCCGCGCATGTCGACGCTGTCGGGCTTCCGCCGCCGTGGCTACACCCCGGCATCGATCCGCAAC
TTCTGCGAGATGATCGGCACCAACCGTTCCGACGGCGTGGTCGACTTCGGCATGCTCGAGTTCAGCATCCGTCAGGACCT
GGACGCCAACGCCCCGCGCGCCATGTGCGTGCTGCGTCCGTTGAAAGTCGTGATCACCAACTACCCGGAAGATCAGGTCG
AGAACCTCGAACTGCCGCGTCATCCGCAGAAAGAAGAACTCGGCGTGCGCCAGCTGCCGTTCGCCCGTGAAATCTACATC
GACCGCGATGACTTCATGGAAGAGCCGCCGAAGGGCTACAAGCGCCTGGAGCCGAACGGCGAAGTGCGTCTGCGCGGCAG
CTACGTGATCCGTGCCGACGAAGCGATCAAGGACGCCGACGGCAACATTGTCGAGCTGCGTTGCTCGTACGATCCGGACA
CCCTGGGCAAGAACCCTGAAGGCCGCAAGGTCAAGGGCGTGATCCACTGGGTGCCGGCCGCTGCCAGCATCGAGTGCGAA
GTGCGTCTGTACGATCGCCTGTTCCGTTCTCCGAACCCGGAGAAGGCCGAAGACAGCGCGAGTTTCCTGGACAACATCAA
CCCTGGCTCACTGCAAGTGCTGACCGGTTGTCGTGCCGAGCCTTCGCTGGGCAATGCACAGCCGGAAGACCGTTTCCAGT
TCGAGCGCGAAGGCTACTTCGTCGCGGATATCAAGGACTCGAAACCAGGTCAGCCGGTATTCAACCGTACCGTGACCCTG
CGCGATTCGTGGGGCCAGTGA

Upstream 100 bases:

>100_bases
TAAGCCCTGCTCTGTCAGGGGCTTGACAGCATCGGCTATGATAGCGGCTTTGTTTTGTCAGGCCCGTGTCCCGGCCGCGC
ACTGTACGTTCAAGGATCCT

Downstream 100 bases:

>100_bases
TCAAGTCTTAAGGAAACACCGTGCTTACGATCTACAACACGCTCACCAAGAGCAAAGAAGTCTTCAAGCCGCTGGATGGC
AACAAGGTGCGCATGTATGT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSKPTVDPTSNSKTGPVTPVNFLRPIIQADLDSGKHTQIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGVTHLRFDDT
NPAKEDQEYIDAIESDVKWLGFEWSGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAKEYRGSLTEPGKNSPFRDR
SVEENLDWFARMRAGEFPDGARVLRAKIDMASPNMNLRDPIMYRIRHAHHHQTGDKWCIYPNYDFTHGQSDAIEGITHSI
CTLEFESHRPLYEWFLDALPVPARPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPASIRN
FCEMIGTNRSDGVVDFGMLEFSIRQDLDANAPRAMCVLRPLKVVITNYPEDQVENLELPRHPQKEELGVRQLPFAREIYI
DRDDFMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAAASIECE
VRLYDRLFRSPNPEKAEDSASFLDNINPGSLQVLTGCRAEPSLGNAQPEDRFQFEREGYFVADIKDSKPGQPVFNRTVTL
RDSWGQ

Sequences:

>Translated_566_residues
MSKPTVDPTSNSKTGPVTPVNFLRPIIQADLDSGKHTQIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGVTHLRFDDT
NPAKEDQEYIDAIESDVKWLGFEWSGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAKEYRGSLTEPGKNSPFRDR
SVEENLDWFARMRAGEFPDGARVLRAKIDMASPNMNLRDPIMYRIRHAHHHQTGDKWCIYPNYDFTHGQSDAIEGITHSI
CTLEFESHRPLYEWFLDALPVPARPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPASIRN
FCEMIGTNRSDGVVDFGMLEFSIRQDLDANAPRAMCVLRPLKVVITNYPEDQVENLELPRHPQKEELGVRQLPFAREIYI
DRDDFMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAAASIECE
VRLYDRLFRSPNPEKAEDSASFLDNINPGSLQVLTGCRAEPSLGNAQPEDRFQFEREGYFVADIKDSKPGQPVFNRTVTL
RDSWGQ
>Mature_565_residues
SKPTVDPTSNSKTGPVTPVNFLRPIIQADLDSGKHTQIVTRFPPEPNGYLHIGHAKSICVNFGLAQEFGGVTHLRFDDTN
PAKEDQEYIDAIESDVKWLGFEWSGEVRYASQYFDQLHDWAVELIKAGKAYVDDLTPEQAKEYRGSLTEPGKNSPFRDRS
VEENLDWFARMRAGEFPDGARVLRAKIDMASPNMNLRDPIMYRIRHAHHHQTGDKWCIYPNYDFTHGQSDAIEGITHSIC
TLEFESHRPLYEWFLDALPVPARPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDPRMSTLSGFRRRGYTPASIRNF
CEMIGTNRSDGVVDFGMLEFSIRQDLDANAPRAMCVLRPLKVVITNYPEDQVENLELPRHPQKEELGVRQLPFAREIYID
RDDFMEEPPKGYKRLEPNGEVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAAASIECEV
RLYDRLFRSPNPEKAEDSASFLDNINPGSLQVLTGCRAEPSLGNAQPEDRFQFEREGYFVADIKDSKPGQPVFNRTVTLR
DSWGQ

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=531, Percent_Identity=46.5160075329567, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI62241042, Length=532, Percent_Identity=33.4586466165414, Blast_Score=265, Evalue=8e-71,
Organism=Escherichia coli, GI1786895, Length=549, Percent_Identity=62.8415300546448, Blast_Score=718, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=313, Percent_Identity=25.2396166134185, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543332, Length=535, Percent_Identity=42.9906542056075, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17511007, Length=525, Percent_Identity=31.4285714285714, Blast_Score=238, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6324742, Length=564, Percent_Identity=41.1347517730496, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321192, Length=531, Percent_Identity=35.2165725047081, Blast_Score=299, Evalue=9e-82,
Organism=Drosophila melanogaster, GI17864488, Length=532, Percent_Identity=43.796992481203, Blast_Score=436, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24649466, Length=527, Percent_Identity=34.7248576850095, Blast_Score=270, Evalue=2e-72,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64755; Mature: 64624

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPTVDPTSNSKTGPVTPVNFLRPIIQADLDSGKHTQIVTRFPPEPNGYLHIGHAKSIC
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCHHEEE
VNFGLAQEFGGVTHLRFDDTNPAKEDQEYIDAIESDVKWLGFEWSGEVRYASQYFDQLHD
EECCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHH
WAVELIKAGKAYVDDLTPEQAKEYRGSLTEPGKNSPFRDRSVEENLDWFARMRAGEFPDG
HHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
ARVLRAKIDMASPNMNLRDPIMYRIRHAHHHQTGDKWCIYPNYDFTHGQSDAIEGITHSI
HHHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHE
CTLEFESHRPLYEWFLDALPVPARPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDP
EEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
RMSTLSGFRRRGYTPASIRNFCEMIGTNRSDGVVDFGMLEFSIRQDLDANAPRAMCVLRP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEHHEEEHHHHCCCCCCCHHHHHHHH
LKVVITNYPEDQVENLELPRHPQKEELGVRQLPFAREIYIDRDDFMEEPPKGYKRLEPNG
HHHEEECCCHHHHHCCCCCCCCCHHHCCCCCCCCHHEEEECCHHHHCCCCCCHHCCCCCC
EVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAAASIECE
CEEEECEEEEEECHHHHCCCCCEEEEEECCCCHHCCCCCCCCEEEEEEEEECCCCCEEEE
VRLYDRLFRSPNPEKAEDSASFLDNINPGSLQVLTGCRAEPSLGNAQPEDRFQFEREGYF
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCEE
VADIKDSKPGQPVFNRTVTLRDSWGQ
EEEECCCCCCCCHHCCEEEEECCCCC
>Mature Secondary Structure 
SKPTVDPTSNSKTGPVTPVNFLRPIIQADLDSGKHTQIVTRFPPEPNGYLHIGHAKSIC
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCHHEEE
VNFGLAQEFGGVTHLRFDDTNPAKEDQEYIDAIESDVKWLGFEWSGEVRYASQYFDQLHD
EECCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHH
WAVELIKAGKAYVDDLTPEQAKEYRGSLTEPGKNSPFRDRSVEENLDWFARMRAGEFPDG
HHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
ARVLRAKIDMASPNMNLRDPIMYRIRHAHHHQTGDKWCIYPNYDFTHGQSDAIEGITHSI
HHHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHE
CTLEFESHRPLYEWFLDALPVPARPRQYEFSRLNLNYTITSKRKLKQLVDEKHVNGWDDP
EEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
RMSTLSGFRRRGYTPASIRNFCEMIGTNRSDGVVDFGMLEFSIRQDLDANAPRAMCVLRP
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEHHEEEHHHHCCCCCCCHHHHHHHH
LKVVITNYPEDQVENLELPRHPQKEELGVRQLPFAREIYIDRDDFMEEPPKGYKRLEPNG
HHHEEECCCHHHHHCCCCCCCCCHHHCCCCCCCCHHEEEECCHHHHCCCCCCHHCCCCCC
EVRLRGSYVIRADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAAASIECE
CEEEECEEEEEECHHHHCCCCCEEEEEECCCCHHCCCCCCCCEEEEEEEEECCCCCEEEE
VRLYDRLFRSPNPEKAEDSASFLDNINPGSLQVLTGCRAEPSLGNAQPEDRFQFEREGYF
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCEE
VADIKDSKPGQPVFNRTVTLRDSWGQ
EEEECCCCCCCCHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]