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The map label for this gene is cysS [H]

Identifier: 77459860

GI number: 77459860

Start: 4113475

End: 4114857

Strand: Reverse

Name: cysS [H]

Synonym: Pfl01_3638

Alternate gene names: 77459860

Gene position: 4114857-4113475 (Counterclockwise)

Preceding gene: 77459861

Following gene: 77459859

Centisome position: 63.91

GC content: 61.53

Gene sequence:

>1383_bases
GTGCTTACGATCTACAACACGCTCACCAAGAGCAAAGAAGTCTTCAAGCCGCTGGATGGCAACAAGGTGCGCATGTATGT
CTGCGGGATGACCGTGTACGACTACTGCCACCTGGGCCACGGCCGCAGCATGGTCGCGTTCGACCTGGTGACCCGCTGGT
TGCGGTTCAGCGGTTATGACCTGACCTACGTGCGCAACATCACCGACATCGACGACAAGATCATCAACCGGGCCAACGAG
AACGGTGAATCGTTCGAAGCGTTGACCGAGCGCATGATCGCGGCGATGCACGAAGACGAAGCGCGCCTGAACATCAAGAA
GCCGGACATGGAGCCGCGCGCCACGGATCATATTCCGGGCATGCACGCGATGATCCAGACCCTGATCGACAAAGGTTACG
CCTACGCCCCGGGCAATGGCGACGTGTACTACCGCGTCGGCAAGTTCATGGGCTACGGCAAGCTCTCGCGCAAGAAGATC
GAAGACCTGCGCATCGGTGCGCGGATCGAGGTCGACGAAGCCAAGGAAGATCCGCTGGACTTCGTGCTCTGGAAAGGCGT
CAAGCCTGGCGAGCCGAGCTGGGAATCGCCGTGGGGCGCCGGGCGTCCGGGCTGGCACATCGAGTGCTCGGTGATGTCCA
CCTGCTGCCTCGGCGAGACTTTCGACATTCATGGCGGCGGCAGCGACCTCGAGTTTCCGCACCACGAAAACGAAATCGCC
CAGAGCGAAGCGGCCACCGGCAAGACCTACGCCAACGCGTGGATGCACTGCGGCATGATCCGTATCAATGGCGAGAAGAT
GTCCAAGTCCTTGAACAACTTCTTCACCATTCGCGACGTGCTCGACAAGTACCACCCGGAAGTCGTGCGTTACCTGCTGG
TGTCGAGCCACTACCGCAGCGCGATCAACTATTCGGAAGACAACCTCAAGGACGCCAAGGGCGCACTGGAGCGTTTCTAC
CATGCGTTGAAAGGCTTGCCGAAAGTGGCACCGGCGGGTGGCGAAGCCTTCGTCGAGCGTTTCACCCAGGTGATGAACGA
CGACTTCGGCACGCCGGAAGCCTGTGCGGTGCTGTTCGAGATGGTTCGCGAGATCAACCGTCTGCGCGAGAGCGATCTCG
ATGCGGCGGCCGGTCTGGCGGCGCGCTTGAAGGAACTGGCCAGCGTGCTAGGTGTGTTGCAGCTTGAAGCCGATGACTTC
CTGCAGGCCGGTGCCGAAGGGCGGGTCGATGCGGCTGAGGTTGATGCACTGATCCAGGCGCGCCTGACTGCCCGTGCCAA
CAAGGACTGGGCCGAATCCGACCGCATCCGCGACCAGCTCACCGCCATGGGCGTGGTGCTGGAAGACGGCAAGGGCGGCA
CGACCTGGCGTCTGGCTGACTGA

Upstream 100 bases:

>100_bases
TCGCGGATATCAAGGACTCGAAACCAGGTCAGCCGGTATTCAACCGTACCGTGACCCTGCGCGATTCGTGGGGCCAGTGA
TCAAGTCTTAAGGAAACACC

Downstream 100 bases:

>100_bases
TTGCTGCGCCTGTTACAAACAAAACCCGCCTTGTGCGGGTTTTTGTTTGGCTGCGAGAAGAGCCCCTCACCCTCTCCCAG
AGGGAGAGGGGACTGAATGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYDLTYVRNITDIDDKIINRANE
NGESFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKI
EDLRIGARIEVDEAKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVSSHYRSAINYSEDNLKDAKGALERFY
HALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFEMVREINRLRESDLDAAAGLAARLKELASVLGVLQLEADDF
LQAGAEGRVDAAEVDALIQARLTARANKDWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD

Sequences:

>Translated_460_residues
MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYDLTYVRNITDIDDKIINRANE
NGESFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKI
EDLRIGARIEVDEAKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVSSHYRSAINYSEDNLKDAKGALERFY
HALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFEMVREINRLRESDLDAAAGLAARLKELASVLGVLQLEADDF
LQAGAEGRVDAAEVDALIQARLTARANKDWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD
>Mature_460_residues
MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYDLTYVRNITDIDDKIINRANE
NGESFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPGMHAMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKI
EDLRIGARIEVDEAKEDPLDFVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
QSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVSSHYRSAINYSEDNLKDAKGALERFY
HALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFEMVREINRLRESDLDAAAGLAARLKELASVLGVLQLEADDF
LQAGAEGRVDAAEVDALIQARLTARANKDWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=314, Percent_Identity=42.3566878980892, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI62240992, Length=281, Percent_Identity=38.0782918149466, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI21269877, Length=281, Percent_Identity=38.0782918149466, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI10835051, Length=281, Percent_Identity=38.0782918149466, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI303304987, Length=281, Percent_Identity=38.0782918149466, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1786737, Length=459, Percent_Identity=61.437908496732, Blast_Score=563, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17509795, Length=432, Percent_Identity=31.4814814814815, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17509797, Length=432, Percent_Identity=31.4814814814815, Blast_Score=188, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324082, Length=354, Percent_Identity=33.6158192090396, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19922218, Length=503, Percent_Identity=33.0019880715706, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19922364, Length=279, Percent_Identity=39.426523297491, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51554; Mature: 51554

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYD
CEEEEHHHHCCHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LTYVRNITDIDDKIINRANENGESFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPG
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
MHAMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKIEDLRIGARIEVDEAKEDPLD
HHHHHHHHHHCCCEECCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
FVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCHHHHH
QSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVSSHYRS
HHHHCCCHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYSEDNLKDAKGALERFYHALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFE
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
MVREINRLRESDLDAAAGLAARLKELASVLGVLQLEADDFLQAGAEGRVDAAEVDALIQA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHH
RLTARANKDWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD
HHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEECC
>Mature Secondary Structure
MLTIYNTLTKSKEVFKPLDGNKVRMYVCGMTVYDYCHLGHGRSMVAFDLVTRWLRFSGYD
CEEEEHHHHCCHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LTYVRNITDIDDKIINRANENGESFEALTERMIAAMHEDEARLNIKKPDMEPRATDHIPG
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCH
MHAMIQTLIDKGYAYAPGNGDVYYRVGKFMGYGKLSRKKIEDLRIGARIEVDEAKEDPLD
HHHHHHHHHHCCCEECCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
FVLWKGVKPGEPSWESPWGAGRPGWHIECSVMSTCCLGETFDIHGGGSDLEFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCHHHHH
QSEAATGKTYANAWMHCGMIRINGEKMSKSLNNFFTIRDVLDKYHPEVVRYLLVSSHYRS
HHHHCCCHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYSEDNLKDAKGALERFYHALKGLPKVAPAGGEAFVERFTQVMNDDFGTPEACAVLFE
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
MVREINRLRESDLDAAAGLAARLKELASVLGVLQLEADDFLQAGAEGRVDAAEVDALIQA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHH
RLTARANKDWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD
HHHHHCCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA