Click here to switch to the map view.

The map label for this gene is czcC [H]

Identifier: 77459845

GI number: 77459845

Start: 4096433

End: 4097680

Strand: Reverse

Name: czcC [H]

Synonym: Pfl01_3623

Alternate gene names: 77459845

Gene position: 4097680-4096433 (Counterclockwise)

Preceding gene: 77459852

Following gene: 77459844

Centisome position: 63.64

GC content: 65.46

Gene sequence:

>1248_bases
TTGCCCGGTTTAATTGAACTGACGGCGCGATCACGCCTGAAAAAAACCGCCAGCGGCCTGTTGTTGCTGGCTTGTACCAG
CCTTGCCAGCGCATCGACTTTGACGCTGGATCAGGCGTTGCAAACCGCCTTCGCCAGCAACCCGGAGCTGGCCGCCGCGC
AGTGGGAAATCGGCATTGCCGAAGGTGACCGCAAGCAGGCCGGGCTGATCCCCAACCCCGAGGTGTCGTGGGAGGCCGAA
GACACCCGGCGTGAATCGCGCACCACCACGGTGATGCTCAGCCAGCCGATCGAGCTGGGCGGCAAGCGCGGCGCGCGGAT
TGATGTGGCGAGTCGTGCCCAGGACGCCGCCGGCATCGAGCTGGAGCGCAAGCGCAACGTCCTGCGCGCCGACGTGCTTC
AAGCGTTCAACGGTGCGCAAACCGCGCAGCAACGTTTGCAACTGGCCCGGCAGTCGCTGCAACTCGCCGAGCACGGTGTG
CGTGTGGCGCAGGGGCGGATCGAGGCGGGCAAGTCGTCGCCGGTGGAAGGCACGCGGGCGCAAGTGCAGCTTTCGGAAGT
GCGCCTGGAATTGAGCCGCGCCGAGCGTGATCAGGCCAATGCGTACCAGCAATTGGCACAGGTCATGGGCGCACCGTTGC
CGACGTCGACCACGGTGCAGACCGCGACTCAAAGTCTGCCCAGCGTACCGCCGCCCACCCGTTTGCTTGAGCGTCTGAAC
GAAACAGCGGAGCTGCGGCTGGCCAGGTTGCAGATCGACCAGCGCGAAGCGTCGCTGGGGCTGGAAAAGTCCCAGCGGAT
TCCCGATCTCACCGTCAGCATCGGCAGCCAGTACAGCGAAACCGAGCGCGAGCGGGTCAACGTGGTCGGGCTGTCGATGC
CGATTCCGCTGTTCAACCGCAATCAGGGCAACGTGCTGGCGGCGGCGCGGCGTACCGATCAGGCGCGGGACCTGCGCAAC
GCCACCGAACTGCGCTTGCGCACGGAAATCCAGACCACGCTGGCGCAATGGCAGACCGCCAACGGCGAAATCCAGACATT
CGACCGGATCATCCTGCCCGCCGCGCAAAGTGCGGTCGACAGTGCCACTCGCGGTTTCGAAATGGGCAAGTTCGGCTTCC
TCGACGTGCTCGACGCCCAGCGCACATTGATCGCCGCTCGCAGCCAATACATCCAGGCGGTGAGCGAGGCGACCGACGCC
CGGGTCCGCATCGAACGCATCTTCGGCGACCTCAGCGCCAACCCTTGA

Upstream 100 bases:

>100_bases
ACCGTGGATAACGGATTTGTAATGTTCACGTCACCTTGTCGATAAGTTCAAAACCCTACCGTGGCGCCATCAACGATTCT
TGATTGAAGGAAGCCTTCCA

Downstream 100 bases:

>100_bases
ATTTCAACGTTCTGATGACTGCGCGATGGTTTGGCGCAGAGGAGTTTCCATGGATAAAAAACTGATCGTGGTCGCTGCGG
CGACCTTGGCGCTGGGCATT

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MPGLIELTARSRLKKTASGLLLLACTSLASASTLTLDQALQTAFASNPELAAAQWEIGIAEGDRKQAGLIPNPEVSWEAE
DTRRESRTTTVMLSQPIELGGKRGARIDVASRAQDAAGIELERKRNVLRADVLQAFNGAQTAQQRLQLARQSLQLAEHGV
RVAQGRIEAGKSSPVEGTRAQVQLSEVRLELSRAERDQANAYQQLAQVMGAPLPTSTTVQTATQSLPSVPPPTRLLERLN
ETAELRLARLQIDQREASLGLEKSQRIPDLTVSIGSQYSETERERVNVVGLSMPIPLFNRNQGNVLAAARRTDQARDLRN
ATELRLRTEIQTTLAQWQTANGEIQTFDRIILPAAQSAVDSATRGFEMGKFGFLDVLDAQRTLIAARSQYIQAVSEATDA
RVRIERIFGDLSANP

Sequences:

>Translated_415_residues
MPGLIELTARSRLKKTASGLLLLACTSLASASTLTLDQALQTAFASNPELAAAQWEIGIAEGDRKQAGLIPNPEVSWEAE
DTRRESRTTTVMLSQPIELGGKRGARIDVASRAQDAAGIELERKRNVLRADVLQAFNGAQTAQQRLQLARQSLQLAEHGV
RVAQGRIEAGKSSPVEGTRAQVQLSEVRLELSRAERDQANAYQQLAQVMGAPLPTSTTVQTATQSLPSVPPPTRLLERLN
ETAELRLARLQIDQREASLGLEKSQRIPDLTVSIGSQYSETERERVNVVGLSMPIPLFNRNQGNVLAAARRTDQARDLRN
ATELRLRTEIQTTLAQWQTANGEIQTFDRIILPAAQSAVDSATRGFEMGKFGFLDVLDAQRTLIAARSQYIQAVSEATDA
RVRIERIFGDLSANP
>Mature_414_residues
PGLIELTARSRLKKTASGLLLLACTSLASASTLTLDQALQTAFASNPELAAAQWEIGIAEGDRKQAGLIPNPEVSWEAED
TRRESRTTTVMLSQPIELGGKRGARIDVASRAQDAAGIELERKRNVLRADVLQAFNGAQTAQQRLQLARQSLQLAEHGVR
VAQGRIEAGKSSPVEGTRAQVQLSEVRLELSRAERDQANAYQQLAQVMGAPLPTSTTVQTATQSLPSVPPPTRLLERLNE
TAELRLARLQIDQREASLGLEKSQRIPDLTVSIGSQYSETERERVNVVGLSMPIPLFNRNQGNVLAAARRTDQARDLRNA
TELRLRTEIQTTLAQWQTANGEIQTFDRIILPAAQSAVDSATRGFEMGKFGFLDVLDAQRTLIAARSQYIQAVSEATDAR
VRIERIFGDLSANP

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45359; Mature: 45228

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLIELTARSRLKKTASGLLLLACTSLASASTLTLDQALQTAFASNPELAAAQWEIGIA
CCCEEEHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
EGDRKQAGLIPNPEVSWEAEDTRRESRTTTVMLSQPIELGGKRGARIDVASRAQDAAGIE
CCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCHHCCCCCCCEEEHHHCCCCCCCCC
LERKRNVLRADVLQAFNGAQTAQQRLQLARQSLQLAEHGVRVAQGRIEAGKSSPVEGTRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCHHCCCCCCCCCCCHH
QVQLSEVRLELSRAERDQANAYQQLAQVMGAPLPTSTTVQTATQSLPSVPPPTRLLERLN
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHC
ETAELRLARLQIDQREASLGLEKSQRIPDLTVSIGSQYSETERERVNVVGLSMPIPLFNR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCCHHHHHHHEEEEEEECCCCCCCC
NQGNVLAAARRTDQARDLRNATELRLRTEIQTTLAQWQTANGEIQTFDRIILPAAQSAVD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SATRGFEMGKFGFLDVLDAQRTLIAARSQYIQAVSEATDARVRIERIFGDLSANP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PGLIELTARSRLKKTASGLLLLACTSLASASTLTLDQALQTAFASNPELAAAQWEIGIA
CCEEEHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
EGDRKQAGLIPNPEVSWEAEDTRRESRTTTVMLSQPIELGGKRGARIDVASRAQDAAGIE
CCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCHHCCCCCCCEEEHHHCCCCCCCCC
LERKRNVLRADVLQAFNGAQTAQQRLQLARQSLQLAEHGVRVAQGRIEAGKSSPVEGTRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHCHHCCCCCCCCCCCHH
QVQLSEVRLELSRAERDQANAYQQLAQVMGAPLPTSTTVQTATQSLPSVPPPTRLLERLN
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHC
ETAELRLARLQIDQREASLGLEKSQRIPDLTVSIGSQYSETERERVNVVGLSMPIPLFNR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCCHHHHHHHEEEEEEECCCCCCCC
NQGNVLAAARRTDQARDLRNATELRLRTEIQTTLAQWQTANGEIQTFDRIILPAAQSAVD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SATRGFEMGKFGFLDVLDAQRTLIAARSQYIQAVSEATDARVRIERIFGDLSANP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]