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The map label for this gene is czcB [H]

Identifier: 77459844

GI number: 77459844

Start: 4095190

End: 4096383

Strand: Reverse

Name: czcB [H]

Synonym: Pfl01_3622

Alternate gene names: 77459844

Gene position: 4096383-4095190 (Counterclockwise)

Preceding gene: 77459845

Following gene: 77459843

Centisome position: 63.62

GC content: 65.24

Gene sequence:

>1194_bases
ATGGATAAAAAACTGATCGTGGTCGCTGCGGCGACCTTGGCGCTGGGCATTGGCCTCGGCGCGATGTGGAGCGGCAATGC
GTCTGTCGATGCGCATGCCGATGAAGCGGCGGAGCACGCCGACCATGCCGAAGAAGGCGCCGCCGCTGACGGCGGGCACG
ACGAAGAAGGGCACATCGAACTGACGGCCGAGCAGATCGCGGCGGCGGGGATTCAACTGGCCGCCGCCCAGGCGCATAAC
TTCAGCCTCGGTCTGTCGTTCCCCGGCGAAGTGCGCTTCGACGAAGACCGCACCGCGCATGTGGTGCCGCGTGTGCCGGG
CGTGGTCGAGTTGGTGTCGGTCAACCTTGGACAGTCGGTGAAGAAAGGCCAGTTGCTGGCCGTGATCGCCAGTCAGCAGA
TCTCCGATCAGCGCAGCGAGCAGGCGGCCGCGCAACGCCGTCTGGCCCTGGCCCGCACGACGTTCGAGCGCGAGAGGAAA
CTGTGGCAGGACAAGATCTCCGCCGAGCAGGATTTCCTCCAGGCACGTCAGGCCCTGGAAGAAGCCGAGATTGCGGTGAG
CAACGCCCGGCAAAAGATCAGCGTGCTCAGTGGCAGCGTGGTTGCCACCGGAGGAAATCGCTATGAACTGCGCGCGCCGT
TCGACGGTGTGGTGGTGGAAAAGCACCTGACGCCGGGGGAGGTGGTCGACGAAACCACGGCAGCGTTCACGCTCTCGGAT
TTGTCGCGGGTGTGGGTCACGTTCGGCGTTTCGCCCAAGGACCTGAACAAGGTGCAAGTGGGCAAACCCGTCACCGTCAG
CGCGGCGGAATTGAACGCCGAAGTCAGCGGCACCGTGACCTACGTCGGCAGCCTGCTCGGCGAACAGACCCGCACCGCGA
CCGTGCGCGTCACCCTGGAAAACCCGCAAGGCTCCTGGCGCCCGGGCCTGTTTGTCACGGCGCTGGTCGCTACCGACAGT
CGCCAGGCCAAAGTCGCCGTACCGGAAACCGCAATCCAGACCGTCGAGGACAAGCCCACGGTGTTTGTGCGCACCGACGA
CGGCTTCAAGGCGCAAGCCGTGGAGCTGGGCAGTCGCGCGGCAGGCCAGGTGGAAGTCATCGCCGGACTGGAACCGGGCG
TGCAAGTCGCCAGTGCCGGCAGCTTCGTCCTCAAATCGGAGCTGGGCAAAGCCTCGGCCGAGCACAGTCATTAA

Upstream 100 bases:

>100_bases
GCCCGGGTCCGCATCGAACGCATCTTCGGCGACCTCAGCGCCAACCCTTGAATTTCAACGTTCTGATGACTGCGCGATGG
TTTGGCGCAGAGGAGTTTCC

Downstream 100 bases:

>100_bases
TCGCGGAAGACTCTTATGTTCGAACGCCTCATCCAGTTTGCCATCGAGCAGCGCATCATCGTGCTGCTCGCCGTTCTGCT
CATGGCCGGCCTCGGCATCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MDKKLIVVAAATLALGIGLGAMWSGNASVDAHADEAAEHADHAEEGAAADGGHDEEGHIELTAEQIAAAGIQLAAAQAHN
FSLGLSFPGEVRFDEDRTAHVVPRVPGVVELVSVNLGQSVKKGQLLAVIASQQISDQRSEQAAAQRRLALARTTFERERK
LWQDKISAEQDFLQARQALEEAEIAVSNARQKISVLSGSVVATGGNRYELRAPFDGVVVEKHLTPGEVVDETTAAFTLSD
LSRVWVTFGVSPKDLNKVQVGKPVTVSAAELNAEVSGTVTYVGSLLGEQTRTATVRVTLENPQGSWRPGLFVTALVATDS
RQAKVAVPETAIQTVEDKPTVFVRTDDGFKAQAVELGSRAAGQVEVIAGLEPGVQVASAGSFVLKSELGKASAEHSH

Sequences:

>Translated_397_residues
MDKKLIVVAAATLALGIGLGAMWSGNASVDAHADEAAEHADHAEEGAAADGGHDEEGHIELTAEQIAAAGIQLAAAQAHN
FSLGLSFPGEVRFDEDRTAHVVPRVPGVVELVSVNLGQSVKKGQLLAVIASQQISDQRSEQAAAQRRLALARTTFERERK
LWQDKISAEQDFLQARQALEEAEIAVSNARQKISVLSGSVVATGGNRYELRAPFDGVVVEKHLTPGEVVDETTAAFTLSD
LSRVWVTFGVSPKDLNKVQVGKPVTVSAAELNAEVSGTVTYVGSLLGEQTRTATVRVTLENPQGSWRPGLFVTALVATDS
RQAKVAVPETAIQTVEDKPTVFVRTDDGFKAQAVELGSRAAGQVEVIAGLEPGVQVASAGSFVLKSELGKASAEHSH
>Mature_397_residues
MDKKLIVVAAATLALGIGLGAMWSGNASVDAHADEAAEHADHAEEGAAADGGHDEEGHIELTAEQIAAAGIQLAAAQAHN
FSLGLSFPGEVRFDEDRTAHVVPRVPGVVELVSVNLGQSVKKGQLLAVIASQQISDQRSEQAAAQRRLALARTTFERERK
LWQDKISAEQDFLQARQALEEAEIAVSNARQKISVLSGSVVATGGNRYELRAPFDGVVVEKHLTPGEVVDETTAAFTLSD
LSRVWVTFGVSPKDLNKVQVGKPVTVSAAELNAEVSGTVTYVGSLLGEQTRTATVRVTLENPQGSWRPGLFVTALVATDS
RQAKVAVPETAIQTVEDKPTVFVRTDDGFKAQAVELGSRAAGQVEVIAGLEPGVQVASAGSFVLKSELGKASAEHSH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=324, Percent_Identity=26.2345679012346, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081796, Length=321, Percent_Identity=25.5451713395639, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41829; Mature: 41829

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKLIVVAAATLALGIGLGAMWSGNASVDAHADEAAEHADHAEEGAAADGGHDEEGHIE
CCCCEEEEEHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCEE
LTAEQIAAAGIQLAAAQAHNFSLGLSFPGEVRFDEDRTAHVVPRVPGVVELVSVNLGQSV
EEHHHHHHHCCEEEEECCCCEEEECCCCCCEEECCCCCEEECCCCCCEEEEEEECCCCCC
KKGQLLAVIASQQISDQRSEQAAAQRRLALARTTFERERKLWQDKISAEQDFLQARQALE
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAEIAVSNARQKISVLSGSVVATGGNRYELRAPFDGVVVEKHLTPGEVVDETTAAFTLSD
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEECCCCCHHHHCHHHEEEHHH
LSRVWVTFGVSPKDLNKVQVGKPVTVSAAELNAEVSGTVTYVGSLLGEQTRTATVRVTLE
HHEEEEEECCCHHCCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEEEE
NPQGSWRPGLFVTALVATDSRQAKVAVPETAIQTVEDKPTVFVRTDDGFKAQAVELGSRA
CCCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHCCCCEEEEEECCCCEEHHHHHCCCC
AGQVEVIAGLEPGVQVASAGSFVLKSELGKASAEHSH
CCCEEEEECCCCCCEEECCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDKKLIVVAAATLALGIGLGAMWSGNASVDAHADEAAEHADHAEEGAAADGGHDEEGHIE
CCCCEEEEEHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCEE
LTAEQIAAAGIQLAAAQAHNFSLGLSFPGEVRFDEDRTAHVVPRVPGVVELVSVNLGQSV
EEHHHHHHHCCEEEEECCCCEEEECCCCCCEEECCCCCEEECCCCCCEEEEEEECCCCCC
KKGQLLAVIASQQISDQRSEQAAAQRRLALARTTFERERKLWQDKISAEQDFLQARQALE
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAEIAVSNARQKISVLSGSVVATGGNRYELRAPFDGVVVEKHLTPGEVVDETTAAFTLSD
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCEEEEECCCCCHHHHCHHHEEEHHH
LSRVWVTFGVSPKDLNKVQVGKPVTVSAAELNAEVSGTVTYVGSLLGEQTRTATVRVTLE
HHEEEEEECCCHHCCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEEEE
NPQGSWRPGLFVTALVATDSRQAKVAVPETAIQTVEDKPTVFVRTDDGFKAQAVELGSRA
CCCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHCCCCEEEEEECCCCEEHHHHHCCCC
AGQVEVIAGLEPGVQVASAGSFVLKSELGKASAEHSH
CCCEEEEECCCCCCEEECCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]