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The map label for this gene is nuoN [H]

Identifier: 77459837

GI number: 77459837

Start: 4086439

End: 4087902

Strand: Direct

Name: nuoN [H]

Synonym: Pfl01_3615

Alternate gene names: 77459837

Gene position: 4086439-4087902 (Clockwise)

Preceding gene: 77459836

Following gene: 77459838

Centisome position: 63.47

GC content: 62.91

Gene sequence:

>1464_bases
ATGGAATTCACGATTCAACACTTTATTGCGCTTGCGCCACTGTTGATCACCAGCCTCACCATTATCGTGGTGATGCTGGC
AATCGCCTGGCGCCGCAACCACTCGCAGACCTTCCTGATTTCGGTGGCCGGTCTGAACCTGGCCTTGCTGTCGATCCTGC
CGGCCCTGAAAGTCGCGCCTCTGGCCGTGACCCCGTTGCTGCAGATCGACACCTTTGCCTGCCTGTACATGGCGCTGATC
CTGGTCGCCACCCTCGCCTGTGTCACCCTTGCCCACGCCTACCTCGGCGATGGCGGTTCGGGTTACCCGGGCAACCGTGA
AGAACTGTACCTGCTGATCCTGATGGCCGCCGCCGGTGGCCTGGTTCTGGTCAGCGCGCAGCACCTGGCCGGCTTGTTCA
TCGGTCTGGAACTGCTGTCGGTGCCGGTCTACGGTCTGGTGGCCTACGCCTTCTTCAACAAGCGTTCGCTGGAAGCCGGC
ATCAAGTACATGGTGCTGTCGGCCGCCGGTTCCGCGTTCCTGCTGTTCGGTATGGCGCTGCTGTACGCCGACTCGGGTTC
GCTGAGCTTCGTCGGTATCGGTCAGGCTTTGGCCGCGACCGGTCTGCCAAGCTCGCTGGCACAACTGGGCCTGGGCATGA
TGCTGATCGGTCTGGCGTTCAAGCTGTCGCTGGTACCGTTCCACCTGTGGACGCCGGACGTGTACGAAGGTGCTCCGGCA
CCGGTGGCCGCGTTCCTCGCCACCGCTTCGAAAGTGGCCGTGTTCGCGGTCATGGTTCGCCTGTTCCAGATCTCCCCTGC
CGCAAGCAGTGGCGTACTGAGCAACGTGCTGACCATCATCGCCATTGCCTCGATCCTGTTCGGTAACCTGCTGGCCCTGA
CCCAGAGCAACCTCAAGCGTCTGCTCGGTTACTCCTCCATCGCGCACTTCGGCTACCTGCTGATCGCGCTGGTGGCGAGC
AAGGGCCTGGCGGTGGAGGCCATCGGCGTGTACCTGGTCACCTACGTGATCACCAGCCTCGGCGCCTTCGGTGTGATCAC
CCTGATGTCCTCGCCGTACAACGGCCGTGACGCAGACGCGCTGTACGAATACCGCGGCCTGTTCTGGCGCCGTCCGTACC
TGACCGCCGTCCTGACCGTGATGATGCTGTCCCTGGCCGGTATCCCGCTGACTGCAGGCTTCATCGGCAAGTTCTACATC
ATCGCTACCGGTGTCGAGTCGCACCAATGGTGGCTGGTCGGTTCCCTGGTACTGGGCAGCGCCATCGGCGTCTTCTACTA
CCTGCGCGTGATGGTCACCCTGTACCTGATCGAACCGAACCTGCGCCGCCACGACGCCCAGCTGCACTGGGAACAGAAAG
CAGGCGGCGTGATGCTGCTGGCAATCGCTGTGGTTGCGTTCTTCCTCGGCGTCTACCCGCAACCCCTGCTGACCCTGGTT
CAGCAATCGGGCCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGCAACCGTTCCTCGACACTTCTGCCGCCACGATGCATGGCGTGCAGCAGTGGCTCGGCACCGCCTTCACTCAACTCGC
TTCGGCCCGGTAAGAGCGCT

Downstream 100 bases:

>100_bases
TCGCTCAGCGATAGCTGGCTACAAACAGAAACGGCACCTTCGGGTGCCGTTTTTGCGTTTTGGGAATCCATTACGAGTGT
CCTGCCCCTTCCTGCTTAAA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MEFTIQHFIALAPLLITSLTIIVVMLAIAWRRNHSQTFLISVAGLNLALLSILPALKVAPLAVTPLLQIDTFACLYMALI
LVATLACVTLAHAYLGDGGSGYPGNREELYLLILMAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEAG
IKYMVLSAAGSAFLLFGMALLYADSGSLSFVGIGQALAATGLPSSLAQLGLGMMLIGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVMVRLFQISPAASSGVLSNVLTIIAIASILFGNLLALTQSNLKRLLGYSSIAHFGYLLIALVAS
KGLAVEAIGVYLVTYVITSLGAFGVITLMSSPYNGRDADALYEYRGLFWRRPYLTAVLTVMMLSLAGIPLTAGFIGKFYI
IATGVESHQWWLVGSLVLGSAIGVFYYLRVMVTLYLIEPNLRRHDAQLHWEQKAGGVMLLAIAVVAFFLGVYPQPLLTLV
QQSGLAG

Sequences:

>Translated_487_residues
MEFTIQHFIALAPLLITSLTIIVVMLAIAWRRNHSQTFLISVAGLNLALLSILPALKVAPLAVTPLLQIDTFACLYMALI
LVATLACVTLAHAYLGDGGSGYPGNREELYLLILMAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEAG
IKYMVLSAAGSAFLLFGMALLYADSGSLSFVGIGQALAATGLPSSLAQLGLGMMLIGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVMVRLFQISPAASSGVLSNVLTIIAIASILFGNLLALTQSNLKRLLGYSSIAHFGYLLIALVAS
KGLAVEAIGVYLVTYVITSLGAFGVITLMSSPYNGRDADALYEYRGLFWRRPYLTAVLTVMMLSLAGIPLTAGFIGKFYI
IATGVESHQWWLVGSLVLGSAIGVFYYLRVMVTLYLIEPNLRRHDAQLHWEQKAGGVMLLAIAVVAFFLGVYPQPLLTLV
QQSGLAG
>Mature_487_residues
MEFTIQHFIALAPLLITSLTIIVVMLAIAWRRNHSQTFLISVAGLNLALLSILPALKVAPLAVTPLLQIDTFACLYMALI
LVATLACVTLAHAYLGDGGSGYPGNREELYLLILMAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEAG
IKYMVLSAAGSAFLLFGMALLYADSGSLSFVGIGQALAATGLPSSLAQLGLGMMLIGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVMVRLFQISPAASSGVLSNVLTIIAIASILFGNLLALTQSNLKRLLGYSSIAHFGYLLIALVAS
KGLAVEAIGVYLVTYVITSLGAFGVITLMSSPYNGRDADALYEYRGLFWRRPYLTAVLTVMMLSLAGIPLTAGFIGKFYI
IATGVESHQWWLVGSLVLGSAIGVFYYLRVMVTLYLIEPNLRRHDAQLHWEQKAGGVMLLAIAVVAFFLGVYPQPLLTLV
QQSGLAG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=319, Percent_Identity=28.5266457680251, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI251831117, Length=371, Percent_Identity=23.7196765498652, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI145693160, Length=483, Percent_Identity=58.592132505176, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1788829, Length=354, Percent_Identity=26.5536723163842, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788831, Length=340, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788613, Length=279, Percent_Identity=25.089605734767, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788827, Length=283, Percent_Identity=27.5618374558304, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788614, Length=339, Percent_Identity=24.4837758112094, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51799; Mature: 51799

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTIQHFIALAPLLITSLTIIVVMLAIAWRRNHSQTFLISVAGLNLALLSILPALKVAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCC
LAVTPLLQIDTFACLYMALILVATLACVTLAHAYLGDGGSGYPGNREELYLLILMAAAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEHHCCC
LVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEAGIKYMVLSAAGSAFLLFGMAL
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEHHCCHHHHHHHHHH
LYADSGSLSFVGIGQALAATGLPSSLAQLGLGMMLIGLAFKLSLVPFHLWTPDVYEGAPA
HHCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCC
PVAAFLATASKVAVFAVMVRLFQISPAASSGVLSNVLTIIAIASILFGNLLALTQSNLKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSSIAHFGYLLIALVASKGLAVEAIGVYLVTYVITSLGAFGVITLMSSPYNGRDADA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LYEYRGLFWRRPYLTAVLTVMMLSLAGIPLTAGFIGKFYIIATGVESHQWWLVGSLVLGS
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHEEEEEEECCCCCCHHHHHHHHHHH
AIGVFYYLRVMVTLYLIEPNLRRHDAQLHWEQKAGGVMLLAIAVVAFFLGVYPQPLLTLV
HHHHHHHHHHHHHHHHCCCCCHHCCCCEEEHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
QQSGLAG
HHCCCCC
>Mature Secondary Structure
MEFTIQHFIALAPLLITSLTIIVVMLAIAWRRNHSQTFLISVAGLNLALLSILPALKVAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCC
LAVTPLLQIDTFACLYMALILVATLACVTLAHAYLGDGGSGYPGNREELYLLILMAAAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEHHCCC
LVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEAGIKYMVLSAAGSAFLLFGMAL
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEHHCCHHHHHHHHHH
LYADSGSLSFVGIGQALAATGLPSSLAQLGLGMMLIGLAFKLSLVPFHLWTPDVYEGAPA
HHCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCC
PVAAFLATASKVAVFAVMVRLFQISPAASSGVLSNVLTIIAIASILFGNLLALTQSNLKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSSIAHFGYLLIALVASKGLAVEAIGVYLVTYVITSLGAFGVITLMSSPYNGRDADA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LYEYRGLFWRRPYLTAVLTVMMLSLAGIPLTAGFIGKFYIIATGVESHQWWLVGSLVLGS
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHEEEEEEECCCCCCHHHHHHHHHHH
AIGVFYYLRVMVTLYLIEPNLRRHDAQLHWEQKAGGVMLLAIAVVAFFLGVYPQPLLTLV
HHHHHHHHHHHHHHHHCCCCCHHCCCCEEEHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
QQSGLAG
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA