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The map label for this gene is nuoH [H]

Identifier: 77459831

GI number: 77459831

Start: 4080620

End: 4081627

Strand: Direct

Name: nuoH [H]

Synonym: Pfl01_3609

Alternate gene names: 77459831

Gene position: 4080620-4081627 (Clockwise)

Preceding gene: 77459830

Following gene: 77459832

Centisome position: 63.38

GC content: 59.52

Gene sequence:

>1008_bases
ATGACCTGGTTCACCCCTGAAGTGATCGATGTGATCCTGACGGTCATCAAGGCCATCGTGATCCTGCTGGCCGTGGTGGT
CGCAGGCGCGTTGCTCAGCTTTGTCGAGCGTCGCCTGCTGGGCTGGTGGCAGGACCGTTACGGTCCGAACCGCGTTGGTC
CGTTCGGCATGTTCCAGATCGCGGCCGACATGCTGAAGATGTTCTTCAAGGAAGACTGGACCCCTCCGTTTGCCGACAAG
GTGATCTTCACCCTGGCGCCGGTGGTGGCCATGTCCGCCCTGCTGATCGCGTTCGCGATCATCCCGATCACCCCGACCTG
GGGCGTGGCGGATCTGAACATCGGCCTGCTGTTTTTCTTCGCCATGGCCGGTCTTTCGGTCTACGCGGTGCTGTTCGCCG
GCTGGTCGAGTAACAACAAGTTCGCCCTGCTGGGCAGCTTGCGTGCCTCGGCGCAGACCGTGTCCTACGAAGTGTTCATG
GGCCTGGCCCTGATGGGCATCGTGGTGCAGGTCGGCTCGTTCAACATGCGCGACATCGTCGAGTACCAGGCGCAGAACCT
GTGGTTCATCATTCCGCAGTTCTTCGGCTTCTGTACCTTCTTCATCGCTGGCGTGGCCGTGACTCACCGTCACCCGTTCG
ACCAGCCGGAAGCGGAACAGGAACTGGCCGACGGTTACCACATTGAATACGCCGGTATGAAATGGGGCATGTTCTTCGTC
GGTGAATACATCGGCATCATCCTGATCTCGGCACTGCTGGTCACCCTGTTCTTCGGTGGCTGGCACGGTCCGTTCGGCAT
CCTGCCGCAACTGTCCTTCGTCTGGTTCGCACTGAAGACCGCGTTCTTCATCTTGCTGTTCATCCTGCTGCGCGCTTCCA
TCCCGCGTCCGCGTTATGACCAGGTGATGGATTTCAGCTGGAAATTCTGCCTGCCACTGACCCTGATCAATTTGCTGGTG
ACCGCTGCAATCGTGTTGTGGAACACGCCTGCGGTTGCGGTTCAGTGA

Upstream 100 bases:

>100_bases
AAGAACTGGGCGCAGGTCTGGTGGCATTGCCTGCAGGCATCGCCGGCATTCCACCGGCATTCGCTGGCGTATCCGTTGAT
GGTCTGCAGGAGGCAGCGCA

Downstream 100 bases:

>100_bases
GGATTTGACCCATGTTCAAATATATTGGCGACATCGTTAAGGGTACCGGTACCCAGTTGCGCAGCCTGGTCATGGTCTTC
GGCCATGGCTTTCGCAAGCG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWTPPFADK
VIFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFM
GLALMGIVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFV
GEYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLV
TAAIVLWNTPAVAVQ

Sequences:

>Translated_335_residues
MTWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWTPPFADK
VIFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFM
GLALMGIVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFV
GEYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLV
TAAIVLWNTPAVAVQ
>Mature_334_residues
TWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWTPPFADKV
IFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFMG
LALMGIVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVG
EYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLVT
AAIVLWNTPAVAVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=288, Percent_Identity=39.2361111111111, Blast_Score=207, Evalue=1e-53,
Organism=Escherichia coli, GI1788618, Length=329, Percent_Identity=72.0364741641337, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1789077, Length=312, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37558; Mature: 37427

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AADMLKMFFKEDWTPPFADKVIFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFMGLALMGIVVQVGSFNMRDIV
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFV
HHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCHHHHHHH
GEYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QVMDFSWKFCLPLTLINLLVTAAIVLWNTPAVAVQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TWFTPEVIDVILTVIKAIVILLAVVVAGALLSFVERRLLGWWQDRYGPNRVGPFGMFQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AADMLKMFFKEDWTPPFADKVIFTLAPVVAMSALLIAFAIIPITPTWGVADLNIGLLFFF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AMAGLSVYAVLFAGWSSNNKFALLGSLRASAQTVSYEVFMGLALMGIVVQVGSFNMRDIV
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFV
HHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCHHHHHHH
GEYIGIILISALLVTLFFGGWHGPFGILPQLSFVWFALKTAFFILLFILLRASIPRPRYD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QVMDFSWKFCLPLTLINLLVTAAIVLWNTPAVAVQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA