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The map label for this gene is nuoA [H]

Identifier: 77459825

GI number: 77459825

Start: 4072968

End: 4073381

Strand: Direct

Name: nuoA [H]

Synonym: Pfl01_3603

Alternate gene names: 77459825

Gene position: 4072968-4073381 (Clockwise)

Preceding gene: 77459824

Following gene: 77459826

Centisome position: 63.26

GC content: 57.97

Gene sequence:

>414_bases
ATGCCCGAAGCGACAGGACTCATGGCCCACAACTGGGGCTTTGCCATTTTCCTTCTGGGTGTAGTCGGCCTGTGTGCCTT
CATGCTCGGCGTCTCCAGCCTCCTCGGGTCAAAAGCCTGGGGCCGCAGCAAAAACGAACCGTTCGAGTCCGGCATGCTAC
CTACCGGTGGCGCCCGCTTGCGGCTCTCAGCCAAATTCTATCTGGTCGCGATGCTGTTCGTGATCTTCGATATCGAAGCC
CTCTTTCTCTTTGCATGGTCTGTGTCCGTCCGCGAAAGCGGCTGGACCGGATTCGTCGAAGCTCTCGTTTTCATAGCAAT
TCTGTTGGCAGGTCTTGTCTACCTGTTCCGAGTGGGCGCCCTTGACTGGGCTCCGGAAGCTCGTCGCAAGCGGCAGGCGA
AGCTGAAACAATGA

Upstream 100 bases:

>100_bases
TAGCCATAAAATCAGCGCGATTGATTGCTGCGACATATCGTCACTGCCTTATTTCTTTATCAAGCTCAGAGACCTTTGCT
CTCTGTTAAGGATTTCCAGC

Downstream 100 bases:

>100_bases
GGCTTTGGCAATGCAATACAATCTCACCAGAATCGACCCCGATGCTCCTAACGAGCAGTATCCGATCGGCCAGCGGGAAA
CCGTTTCCGATCCGTTAGAA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MPEATGLMAHNWGFAIFLLGVVGLCAFMLGVSSLLGSKAWGRSKNEPFESGMLPTGGARLRLSAKFYLVAMLFVIFDIEA
LFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLFRVGALDWAPEARRKRQAKLKQ

Sequences:

>Translated_137_residues
MPEATGLMAHNWGFAIFLLGVVGLCAFMLGVSSLLGSKAWGRSKNEPFESGMLPTGGARLRLSAKFYLVAMLFVIFDIEA
LFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLFRVGALDWAPEARRKRQAKLKQ
>Mature_136_residues
PEATGLMAHNWGFAIFLLGVVGLCAFMLGVSSLLGSKAWGRSKNEPFESGMLPTGGARLRLSAKFYLVAMLFVIFDIEAL
FLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLFRVGALDWAPEARRKRQAKLKQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=132, Percent_Identity=65.1515151515152, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15090; Mature: 14959

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEATGLMAHNWGFAIFLLGVVGLCAFMLGVSSLLGSKAWGRSKNEPFESGMLPTGGARL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCEE
RLSAKFYLVAMLFVIFDIEALFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLFRVGA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWAPEARRKRQAKLKQ
CCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PEATGLMAHNWGFAIFLLGVVGLCAFMLGVSSLLGSKAWGRSKNEPFESGMLPTGGARL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCEE
RLSAKFYLVAMLFVIFDIEALFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLFRVGA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWAPEARRKRQAKLKQ
CCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA