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The map label for this gene is virS [H]

Identifier: 77458986

GI number: 77458986

Start: 3186837

End: 3187889

Strand: Direct

Name: virS [H]

Synonym: Pfl01_2761

Alternate gene names: 77458986

Gene position: 3186837-3187889 (Clockwise)

Preceding gene: 77458985

Following gene: 77458987

Centisome position: 49.5

GC content: 59.92

Gene sequence:

>1053_bases
ATGGCTTGCAACCCGTTCATTCGCGCCATCAGCCTGACAGGTTTCGATCCATTTGCCCGGCGTCAGGGACTGGAGCCGAA
CCGGATGCTGCGCCAAGCGTGTCTGTCCGTAGCGTCACTGCAGCGCCCGGAAGACATCCTGTCCTTTCGCAATTACTGCC
GCTTGTTGACACTGTGCCGGCAGCGCTCGAACAACGCATTGTTCGGTTTGGAGTTCGGCCTCCATCAGGGAGTCGACGTC
TTCGGTGACATGTTTTTCCTGATTCACAACACCCGTACCGTCGGCGACGCGCTGCGCGAACTGCGCGCCAATTTCGCCCT
CTACAACGGCGCGGCGCATCTCTATCTGGAGGTGGCCGATGGCATCGCGTTACTGGGTTATCGAGCCGATGAGCAGGAGA
TCGACGGCCTCGCTCAGGCCGAAGAGCTGGCGTGCGGGGTCGGTCTGCGCCTGATGCAAACCCTGGCCAGTGCACCATGG
CAACCCGAGGCAATCATGCTCCGCCATGCGCCTTTGGCGGATGAAGGCCTCTATCGGCAGGCGCTAAACATCACGCCGAC
GTTTTCAGCCGCCCACACGGGATTGCTCTTCAATGCCAGTGTGCTCGCGCAGCCGCTGGATTGCGCCAGTGAAGTCTTGC
ATCAGCTCATCGCTGAACATTTGGCAGGTATTGAACGTCTGTCCACCGATGCCATGCCGGGATACGTCAGGCAATTGCTG
CGCAATCTGTTGCCCAGCGGACGCGCGACGATCGACAGAGTGGCCGATTGCATGGCCGTCACCCCGAGATCCTTGCAGCG
CCACCTGGCTGAGGAAAACACCTCTTTTCAGCAGTTGCTGGACGAGACGCGCCAGCAGTTGGCGCGCAAATACCTGCAGG
TCCCGACGATCAGTCTGCCGCAGGTAGCGCACCTGCTGGGCTACGCCGATGTCAGTACATTCTCGCGGGCTTTTCATCGA
TGGTTTGGGGTGTCGGTGCTGGAGTGGTGCAGGCAATTCGGTGTGAACAGACAGCCCTTGCTGCTTCGAAATCGAGCGAA
AGAGCGACCTTGA

Upstream 100 bases:

>100_bases
CGCCGACCTGAGCGCGTTTTCCCGGGCATTCACGCGCTGGAACGGGGTCAGCCCGCAGCAGTGGAAACAACGCATGCAAC
ACTTACCTCGGTAAATCGAC

Downstream 100 bases:

>100_bases
GCGTATTGAAACTGGAACTGTTTCGTATTGGAAGTGAGCACTTGTAGCAAGTTGATTGCAGTTAGGAGGAGTTATCGGCA
AAAAATGGACGCTTGTGACA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MACNPFIRAISLTGFDPFARRQGLEPNRMLRQACLSVASLQRPEDILSFRNYCRLLTLCRQRSNNALFGLEFGLHQGVDV
FGDMFFLIHNTRTVGDALRELRANFALYNGAAHLYLEVADGIALLGYRADEQEIDGLAQAEELACGVGLRLMQTLASAPW
QPEAIMLRHAPLADEGLYRQALNITPTFSAAHTGLLFNASVLAQPLDCASEVLHQLIAEHLAGIERLSTDAMPGYVRQLL
RNLLPSGRATIDRVADCMAVTPRSLQRHLAEENTSFQQLLDETRQQLARKYLQVPTISLPQVAHLLGYADVSTFSRAFHR
WFGVSVLEWCRQFGVNRQPLLLRNRAKERP

Sequences:

>Translated_350_residues
MACNPFIRAISLTGFDPFARRQGLEPNRMLRQACLSVASLQRPEDILSFRNYCRLLTLCRQRSNNALFGLEFGLHQGVDV
FGDMFFLIHNTRTVGDALRELRANFALYNGAAHLYLEVADGIALLGYRADEQEIDGLAQAEELACGVGLRLMQTLASAPW
QPEAIMLRHAPLADEGLYRQALNITPTFSAAHTGLLFNASVLAQPLDCASEVLHQLIAEHLAGIERLSTDAMPGYVRQLL
RNLLPSGRATIDRVADCMAVTPRSLQRHLAEENTSFQQLLDETRQQLARKYLQVPTISLPQVAHLLGYADVSTFSRAFHR
WFGVSVLEWCRQFGVNRQPLLLRNRAKERP
>Mature_349_residues
ACNPFIRAISLTGFDPFARRQGLEPNRMLRQACLSVASLQRPEDILSFRNYCRLLTLCRQRSNNALFGLEFGLHQGVDVF
GDMFFLIHNTRTVGDALRELRANFALYNGAAHLYLEVADGIALLGYRADEQEIDGLAQAEELACGVGLRLMQTLASAPWQ
PEAIMLRHAPLADEGLYRQALNITPTFSAAHTGLLFNASVLAQPLDCASEVLHQLIAEHLAGIERLSTDAMPGYVRQLLR
NLLPSGRATIDRVADCMAVTPRSLQRHLAEENTSFQQLLDETRQQLARKYLQVPTISLPQVAHLLGYADVSTFSRAFHRW
FGVSVLEWCRQFGVNRQPLLLRNRAKERP

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39252; Mature: 39120

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACNPFIRAISLTGFDPFARRQGLEPNRMLRQACLSVASLQRPEDILSFRNYCRLLTLCR
CCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QRSNNALFGLEFGLHQGVDVFGDMFFLIHNTRTVGDALRELRANFALYNGAAHLYLEVAD
HCCCCCEEEEECCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHEEEEEHHC
GIALLGYRADEQEIDGLAQAEELACGVGLRLMQTLASAPWQPEAIMLRHAPLADEGLYRQ
CHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
ALNITPTFSAAHTGLLFNASVLAQPLDCASEVLHQLIAEHLAGIERLSTDAMPGYVRQLL
HHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RNLLPSGRATIDRVADCMAVTPRSLQRHLAEENTSFQQLLDETRQQLARKYLQVPTISLP
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVAHLLGYADVSTFSRAFHRWFGVSVLEWCRQFGVNRQPLLLRNRAKERP
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
ACNPFIRAISLTGFDPFARRQGLEPNRMLRQACLSVASLQRPEDILSFRNYCRLLTLCR
CCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QRSNNALFGLEFGLHQGVDVFGDMFFLIHNTRTVGDALRELRANFALYNGAAHLYLEVAD
HCCCCCEEEEECCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHEEEEEHHC
GIALLGYRADEQEIDGLAQAEELACGVGLRLMQTLASAPWQPEAIMLRHAPLADEGLYRQ
CHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
ALNITPTFSAAHTGLLFNASVLAQPLDCASEVLHQLIAEHLAGIERLSTDAMPGYVRQLL
HHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RNLLPSGRATIDRVADCMAVTPRSLQRHLAEENTSFQQLLDETRQQLARKYLQVPTISLP
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVAHLLGYADVSTFSRAFHRWFGVSVLEWCRQFGVNRQPLLLRNRAKERP
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]