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The map label for this gene is virS [H]

Identifier: 77458985

GI number: 77458985

Start: 3185832

End: 3186830

Strand: Direct

Name: virS [H]

Synonym: Pfl01_2760

Alternate gene names: 77458985

Gene position: 3185832-3186830 (Clockwise)

Preceding gene: 77458984

Following gene: 77458986

Centisome position: 49.48

GC content: 61.66

Gene sequence:

>999_bases
ATGTCCACGGTTCGAAGTACTGCGCTGTTGGGGTTCAAGGCGTTTTGTGCCAGTCAGGGCATCGACCCGGCTTCGGCGCT
GGCCGCGGTTGAGCTGCCTGAAGACCCTCTGGATGCTCGACTGTCCGGCGCGCAGTTCAATGCCTTGATTGACTTGTGCG
CCCAGCGTTCGCACAACCCGCTATTCGGCGTGCAGTTCGGCTTGCGCCAGGGCACGCAAAGTCTCGGCACCCTGCTTTAC
GCCATGCGCAGTTCAGGCACGGTCGGCGAGGCGCTGAACCTGCTGACACGTTATTTCCATATCCATAGCGACGGCGCGCT
CGTGCAGCTTGAGCGTCAGGCCGGTAACGCCCTGCTGCTATACGACGTCACGGATGGCACCTTTATTTCGGTCCGCCAGA
CCGTGGAACTGGCGATGGGTATCGCCAGTTGCCTGCTGCGCGAACTGCTCGGGCACGCCTGGCAACCAAAATCGCTGCTG
TTGCGCCACAGTGCTCCGGCCAACCGCCTGGCCTATCGCGCCTTGCTCGGGGTAGCGCCGCGTTTCGACAGCCCGGTCAA
TGCCTGGGTGTTTGATGAGTCATTACTGACGACACCGCTGAGCACGACGGACGCCAGATACCAACAATTGGCCCGGCAAC
ATATCGACGAACTGGCCCGCGTGACGCTGGAGGAATTGCCGTCTTACCTGCAAAAAAGGCTGCGCAATGAACTGGCCCAC
GGCCCGGTCACGCTGCGCGACATGGCCGAGTACATGATGATCAGTCCACGCACCTTGCAGCGCTATCTTCGAGCGCAGGG
CTCTGGATTTCAGGCGCTGCTGGACCAGACACGCCGGTCGATGGCCGCGCGCTACCTCTGCGATTCTTCGCTCAGCCTGA
CGCAAGTGGCGGGTCTGTTGGGTTACGCCGACCTGAGCGCGTTTTCCCGGGCATTCACGCGCTGGAACGGGGTCAGCCCG
CAGCAGTGGAAACAACGCATGCAACACTTACCTCGGTAA

Upstream 100 bases:

>100_bases
TCCGAGCGAGGTGAAAGCTTTGCAGATCGCGCCAGCGATTTTGCAAATCGTGCCAGTTCTTTCCGGCCAGCGGCGGCCGG
TCATTCTGAGGGTTGAGCGG

Downstream 100 bases:

>100_bases
ATCGACATGGCTTGCAACCCGTTCATTCGCGCCATCAGCCTGACAGGTTTCGATCCATTTGCCCGGCGTCAGGGACTGGA
GCCGAACCGGATGCTGCGCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSTVRSTALLGFKAFCASQGIDPASALAAVELPEDPLDARLSGAQFNALIDLCAQRSHNPLFGVQFGLRQGTQSLGTLLY
AMRSSGTVGEALNLLTRYFHIHSDGALVQLERQAGNALLLYDVTDGTFISVRQTVELAMGIASCLLRELLGHAWQPKSLL
LRHSAPANRLAYRALLGVAPRFDSPVNAWVFDESLLTTPLSTTDARYQQLARQHIDELARVTLEELPSYLQKRLRNELAH
GPVTLRDMAEYMMISPRTLQRYLRAQGSGFQALLDQTRRSMAARYLCDSSLSLTQVAGLLGYADLSAFSRAFTRWNGVSP
QQWKQRMQHLPR

Sequences:

>Translated_332_residues
MSTVRSTALLGFKAFCASQGIDPASALAAVELPEDPLDARLSGAQFNALIDLCAQRSHNPLFGVQFGLRQGTQSLGTLLY
AMRSSGTVGEALNLLTRYFHIHSDGALVQLERQAGNALLLYDVTDGTFISVRQTVELAMGIASCLLRELLGHAWQPKSLL
LRHSAPANRLAYRALLGVAPRFDSPVNAWVFDESLLTTPLSTTDARYQQLARQHIDELARVTLEELPSYLQKRLRNELAH
GPVTLRDMAEYMMISPRTLQRYLRAQGSGFQALLDQTRRSMAARYLCDSSLSLTQVAGLLGYADLSAFSRAFTRWNGVSP
QQWKQRMQHLPR
>Mature_331_residues
STVRSTALLGFKAFCASQGIDPASALAAVELPEDPLDARLSGAQFNALIDLCAQRSHNPLFGVQFGLRQGTQSLGTLLYA
MRSSGTVGEALNLLTRYFHIHSDGALVQLERQAGNALLLYDVTDGTFISVRQTVELAMGIASCLLRELLGHAWQPKSLLL
RHSAPANRLAYRALLGVAPRFDSPVNAWVFDESLLTTPLSTTDARYQQLARQHIDELARVTLEELPSYLQKRLRNELAHG
PVTLRDMAEYMMISPRTLQRYLRAQGSGFQALLDQTRRSMAARYLCDSSLSLTQVAGLLGYADLSAFSRAFTRWNGVSPQ
QWKQRMQHLPR

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36819; Mature: 36688

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVRSTALLGFKAFCASQGIDPASALAAVELPEDPLDARLSGAQFNALIDLCAQRSHNP
CCCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCC
LFGVQFGLRQGTQSLGTLLYAMRSSGTVGEALNLLTRYFHIHSDGALVQLERQAGNALLL
EEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
YDVTDGTFISVRQTVELAMGIASCLLRELLGHAWQPKSLLLRHSAPANRLAYRALLGVAP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHCCC
RFDSPVNAWVFDESLLTTPLSTTDARYQQLARQHIDELARVTLEELPSYLQKRLRNELAH
CCCCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPVTLRDMAEYMMISPRTLQRYLRAQGSGFQALLDQTRRSMAARYLCDSSLSLTQVAGLL
CCEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GYADLSAFSRAFTRWNGVSPQQWKQRMQHLPR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
STVRSTALLGFKAFCASQGIDPASALAAVELPEDPLDARLSGAQFNALIDLCAQRSHNP
CCHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCC
LFGVQFGLRQGTQSLGTLLYAMRSSGTVGEALNLLTRYFHIHSDGALVQLERQAGNALLL
EEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
YDVTDGTFISVRQTVELAMGIASCLLRELLGHAWQPKSLLLRHSAPANRLAYRALLGVAP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHCCC
RFDSPVNAWVFDESLLTTPLSTTDARYQQLARQHIDELARVTLEELPSYLQKRLRNELAH
CCCCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPVTLRDMAEYMMISPRTLQRYLRAQGSGFQALLDQTRRSMAARYLCDSSLSLTQVAGLL
CCEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GYADLSAFSRAFTRWNGVSPQQWKQRMQHLPR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]