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The map label for this gene is nfxB [H]

Identifier: 77458984

GI number: 77458984

Start: 3184916

End: 3185512

Strand: Direct

Name: nfxB [H]

Synonym: Pfl01_2759

Alternate gene names: 77458984

Gene position: 3184916-3185512 (Clockwise)

Preceding gene: 77458980

Following gene: 77458985

Centisome position: 49.47

GC content: 56.95

Gene sequence:

>597_bases
ATGAACCTGATTTTCCATGAAGAACACCTGCTCAAATCGTTGACCGTGGCTGTCGTCAACCGGCCGAGGGCAACCATGAA
AGAGCTGGCGCAATTGGCAGGCGTGAGCAAGGCCACCCTGCACCGCTATTGCGGAACACGGGAAAACCTGGTGCAAAGAC
TGGAAGAACACGCCGAAGCAACGCTCAATCTGATTATTCGCCGTGCCGGTTTGCAGCATTTGCAGGCGCTGGACGCGTTA
CGTCGATTGATCCGCGAACACCTCGCCCATCGCGAGTTGTTGGCGTTTCTGATGGCACATTACCGCCCCGACTTTCTCGA
TTTCGAACGGGGCGACACACGCTGGCAGTTTTACCTGGAGGCGCTGGACGGATTTTTTCTGAGAGGCCAGCAACAAGGGT
TGTTTCGCATCGACATCACCGCCGCGATTTTCACCGAGCTGTTCATCACTCTGGTGTATGGCCTGGTGGATGCCGAACAG
CGCGGGCGAGCCGCCAACGCCGATTCGGCACGCACCCTTGAGCAAATGTTCCTGCATGGCGCGCTGGCTGGTAGTCAATT
GCGCGAGGACGCCTGCTTGCCGGAAAAAATGCTCTAA

Upstream 100 bases:

>100_bases
TGAATTTGGTGCGAATGCTACTTTTCAAATCCTAATGAGTCAATAATGTCTCATGTGAGAAATATATGAATCTTACATTA
CGATCGCTTGAGGCTTGGTG

Downstream 100 bases:

>100_bases
CGCTCAAAAATGGGTGAAGGCATCGCTGATGCTGGCGACCGGAGGGTGACTGGAATGATGGACAACGGTGTGGCCAGCTG
GCCGGTGCTGCGAATACAGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MNLIFHEEHLLKSLTVAVVNRPRATMKELAQLAGVSKATLHRYCGTRENLVQRLEEHAEATLNLIIRRAGLQHLQALDAL
RRLIREHLAHRELLAFLMAHYRPDFLDFERGDTRWQFYLEALDGFFLRGQQQGLFRIDITAAIFTELFITLVYGLVDAEQ
RGRAANADSARTLEQMFLHGALAGSQLREDACLPEKML

Sequences:

>Translated_198_residues
MNLIFHEEHLLKSLTVAVVNRPRATMKELAQLAGVSKATLHRYCGTRENLVQRLEEHAEATLNLIIRRAGLQHLQALDAL
RRLIREHLAHRELLAFLMAHYRPDFLDFERGDTRWQFYLEALDGFFLRGQQQGLFRIDITAAIFTELFITLVYGLVDAEQ
RGRAANADSARTLEQMFLHGALAGSQLREDACLPEKML
>Mature_198_residues
MNLIFHEEHLLKSLTVAVVNRPRATMKELAQLAGVSKATLHRYCGTRENLVQRLEEHAEATLNLIIRRAGLQHLQALDAL
RRLIREHLAHRELLAFLMAHYRPDFLDFERGDTRWQFYLEALDGFFLRGQQQGLFRIDITAAIFTELFITLVYGLVDAEQ
RGRAANADSARTLEQMFLHGALAGSQLREDACLPEKML

Specific function: Confers resistance to guinolones. May negatively regulate the expression of genes that are associated with cell permeability to drugs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR000843
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR005471 [H]

Pfam domain/function: PF09339 HTH_IclR [H]

EC number: NA

Molecular weight: Translated: 22722; Mature: 22722

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00356 HTH_LACI_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIFHEEHLLKSLTVAVVNRPRATMKELAQLAGVSKATLHRYCGTRENLVQRLEEHAEA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHH
TLNLIIRRAGLQHLQALDALRRLIREHLAHRELLAFLMAHYRPDFLDFERGDTRWQFYLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ALDGFFLRGQQQGLFRIDITAAIFTELFITLVYGLVDAEQRGRAANADSARTLEQMFLHG
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ALAGSQLREDACLPEKML
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNLIFHEEHLLKSLTVAVVNRPRATMKELAQLAGVSKATLHRYCGTRENLVQRLEEHAEA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHH
TLNLIIRRAGLQHLQALDALRRLIREHLAHRELLAFLMAHYRPDFLDFERGDTRWQFYLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ALDGFFLRGQQQGLFRIDITAAIFTELFITLVYGLVDAEQRGRAANADSARTLEQMFLHG
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ALAGSQLREDACLPEKML
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1330820; 10984043 [H]