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The map label for this gene is nfxB [H]

Identifier: 77458980

GI number: 77458980

Start: 3178408

End: 3178971

Strand: Direct

Name: nfxB [H]

Synonym: Pfl01_2755

Alternate gene names: 77458980

Gene position: 3178408-3178971 (Clockwise)

Preceding gene: 77458977

Following gene: 77458984

Centisome position: 49.37

GC content: 57.62

Gene sequence:

>564_bases
ATGTCCCTGACTCCTCAAGACGAACGACTCATCAAGGCGCTTGCCCTGGCCATCGTTGATCGCCCCCGTGCGACGCTCAA
GGAACTGGCTGAAGCGGCAGGCGTGAGCAAGGCTACGCTGCATCGCTTTTGCGGCACCCGCGACAACTTGGTGCAGATAA
TGGAAAGCCACGGTGAGACGGTGCTGAACCAGATCACCACCACAACCGACCTGCTGCACGGAGAGCCGGTGCAGGCGTTG
CGCAGTTTGATCAATGAGCATTTGGCGCATCGTGAAATGCTGGTTTTCCTGCTCTTTCAGTACCGACCCGACACTTTTCC
AGTCAACGGTGAGGGCGACCGTTGGCAATCTTATGCCGATGCCCTGGATGCTTTTTTTCTGCGCGGCCAGCAATTGGGCG
CATTTCGCATCGATATCACGGCAGCCGTTTTCACAGAGCTGTTCCTGACCATGATCTTCGGAATGGTCGATGCCGAGCGC
CGTGGGCGCGCGGCCAGCGCCAACTCGGCCAATGTGCTGGAACAGATGTTCCTGCACGGTGCCGCTAACGTAAAACCCCA
ATAA

Upstream 100 bases:

>100_bases
TCTCAGATGAAGTAAGTTGCTCAAGTTCTGTGGTTTTCATTGCAGTAATGAGCTTTTCCTGCACAATTCCGAGGACTGAA
ATACGATTCGAGACCGACTG

Downstream 100 bases:

>100_bases
TCCACACTCTATCCTCCTGCAAAAAAGCCCCGTGACCTCTCGGTCTACGGGGCAAAAGGTTGGATGCGCCAACCCAAAGG
AGCTCTTGCCAGGATTTATC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLTPQDERLIKALALAIVDRPRATLKELAEAAGVSKATLHRFCGTRDNLVQIMESHGETVLNQITTTTDLLHGEPVQAL
RSLINEHLAHREMLVFLLFQYRPDTFPVNGEGDRWQSYADALDAFFLRGQQLGAFRIDITAAVFTELFLTMIFGMVDAER
RGRAASANSANVLEQMFLHGAANVKPQ

Sequences:

>Translated_187_residues
MSLTPQDERLIKALALAIVDRPRATLKELAEAAGVSKATLHRFCGTRDNLVQIMESHGETVLNQITTTTDLLHGEPVQAL
RSLINEHLAHREMLVFLLFQYRPDTFPVNGEGDRWQSYADALDAFFLRGQQLGAFRIDITAAVFTELFLTMIFGMVDAER
RGRAASANSANVLEQMFLHGAANVKPQ
>Mature_186_residues
SLTPQDERLIKALALAIVDRPRATLKELAEAAGVSKATLHRFCGTRDNLVQIMESHGETVLNQITTTTDLLHGEPVQALR
SLINEHLAHREMLVFLLFQYRPDTFPVNGEGDRWQSYADALDAFFLRGQQLGAFRIDITAAVFTELFLTMIFGMVDAERR
GRAASANSANVLEQMFLHGAANVKPQ

Specific function: Confers resistance to guinolones. May negatively regulate the expression of genes that are associated with cell permeability to drugs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR000843
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR005471 [H]

Pfam domain/function: PF09339 HTH_IclR [H]

EC number: NA

Molecular weight: Translated: 20823; Mature: 20692

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00356 HTH_LACI_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTPQDERLIKALALAIVDRPRATLKELAEAAGVSKATLHRFCGTRDNLVQIMESHGET
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
VLNQITTTTDLLHGEPVQALRSLINEHLAHREMLVFLLFQYRPDTFPVNGEGDRWQSYAD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ALDAFFLRGQQLGAFRIDITAAVFTELFLTMIFGMVDAERRGRAASANSANVLEQMFLHG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
AANVKPQ
CCCCCCC
>Mature Secondary Structure 
SLTPQDERLIKALALAIVDRPRATLKELAEAAGVSKATLHRFCGTRDNLVQIMESHGET
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
VLNQITTTTDLLHGEPVQALRSLINEHLAHREMLVFLLFQYRPDTFPVNGEGDRWQSYAD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ALDAFFLRGQQLGAFRIDITAAVFTELFLTMIFGMVDAERRGRAASANSANVLEQMFLHG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
AANVKPQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1330820; 10984043 [H]