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The map label for this gene is aofH [H]

Identifier: 77458963

GI number: 77458963

Start: 3155222

End: 3156706

Strand: Direct

Name: aofH [H]

Synonym: Pfl01_2738

Alternate gene names: 77458963

Gene position: 3155222-3156706 (Clockwise)

Preceding gene: 77458962

Following gene: 77458964

Centisome position: 49.01

GC content: 62.09

Gene sequence:

>1485_bases
ATGAGTGCGGATCTCGATCAACTGTCGACGCAATCACGACAGCGACGGTTGTTATTGCAAGCGATCGGAGGCGCAGCCCT
CGCCGGAGGGCTGGGTGTCACCGGGCGTGCGATGGCGCAAATCGAACCTGTAGATACCTCGATACTGGATGTGGTGATCA
TTGGCGCAGGGCTTTCCGGGCTAACCTCCGCCAGAGACCTCCAGGCCGCTGGCTGCGAGTCTTTTGCCGTGCTTGAAGCC
CGCGACCGCGTCGGTGGTCGCACGCTGAACCATGATCTGGGCAATGGCGTGATCTCCGAAGCCGGTGGCCAATGGATCGG
CCCGGGGCAAACGTCGATCGCCGACTTGGCCAGACAGCTCGATGTCGCCACCTTCCCCACCTACTACAAGGGCAAGGCGG
TGTATCTGATGGACGAGGTCAACATCCAGGAAGATCTCAGCGACGGGCCGAATTCCAATACAGAAGTCGTCGCAAAACTG
AACAAGCTCGCCGAAGGCGTCCCCAGCAAAGCGCCGTGGAAAGCCAAGGACGCGGCTGAGCTGGACAAACTGTCGGTCGG
CCAGTGGCTGGCCGGTCAAGGCATCAGCAACGTCGACAAGATCGGCTTCAACATGTCCGTGAGCCTCACCTTCGGTACCA
CGCCGGCCGGCATGGGACTCCTGCATTACCTGGCGATGATCAACTCGTCGGACTGCCGCCTTGAAAAGCTCGAAGGGCTC
CAGGGCGGTGCGCAGGAATCTCGCCTGGCTGGCGGCTCGCAAATTCTCAGTTTGAAGATGGCTCAGGCGCTGGGAGATAA
AATCCGGTTGGCGTGCCCGGTGCGCAAGATTGTCGGTTGGGATCGTGATGTCGTCGAGTTGCACACCGATCAGGGCATCA
TCCGCACGCGGCAGGTAATTGCTGCGCTGAGCCCGGCGTTGTGCAATCAGATCCTCTTCGATCCGCCCCTGCCGTCCGGG
CGTGCCGAGCTGCAGCGGCATTGGCCGGCCCATGCACCGATGCGCAAGACCGTGCACGTCTATGAGCGCCCGTTCTGGCG
CGACCAAGGCCTCAACGGGCAGATTGTGCCAGTGGAAGGTCCGCTGATCTGGGCCTTTGACAACTCCCCGGCGGACGGCA
GCCTGGGTGTGCTCAGCGGCTTCGTCAGGACCGGCCAATTACCCCATGACCCGAAAACGGCGCAGGACATCCTGTCGGCG
ATTTACGCCAGCGCCATGGGCGAACAAGCCCTGCACCCGATTCAGTTTCATGATCTGGACTGGGGCAAGATCGACCCGTG
GAGTTTGAGTTGTATTTCCCCTATGCCCCCCGGTTTCTGGACGCAATGGGGCGAGTACCTGACGCCGGCGGTCGGTCGCC
TGATCTGGTCGGGTACCGAGACTGCGGAAATCTGGGCCGGGGCAATGGACGGTGCGGTCCGCGCCGGACATCGCGCGGCA
ATGGAAGCGCTGCAGGCGTTGCTTCAACCACGGAGGAGCGCCTGA

Upstream 100 bases:

>100_bases
CACGGTTAACCGACATCGCGCCGATTTCACTTTGCTGAATTCCTGATCCGTCATATATTCACATAACATCTGTGATTATA
AATAGAAAACGGAGGTGAAG

Downstream 100 bases:

>100_bases
TGAAGCGGACTATGGTGTTTGGAGTCATCACCGTGAGCGCGGCGTTGGCTGGATCAATAGCGATTTACGGGCCGGAACTG
TGGGCGGGCTATCGTTTCAT

Product: amine oxidase

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSADLDQLSTQSRQRRLLLQAIGGAALAGGLGVTGRAMAQIEPVDTSILDVVIIGAGLSGLTSARDLQAAGCESFAVLEA
RDRVGGRTLNHDLGNGVISEAGGQWIGPGQTSIADLARQLDVATFPTYYKGKAVYLMDEVNIQEDLSDGPNSNTEVVAKL
NKLAEGVPSKAPWKAKDAAELDKLSVGQWLAGQGISNVDKIGFNMSVSLTFGTTPAGMGLLHYLAMINSSDCRLEKLEGL
QGGAQESRLAGGSQILSLKMAQALGDKIRLACPVRKIVGWDRDVVELHTDQGIIRTRQVIAALSPALCNQILFDPPLPSG
RAELQRHWPAHAPMRKTVHVYERPFWRDQGLNGQIVPVEGPLIWAFDNSPADGSLGVLSGFVRTGQLPHDPKTAQDILSA
IYASAMGEQALHPIQFHDLDWGKIDPWSLSCISPMPPGFWTQWGEYLTPAVGRLIWSGTETAEIWAGAMDGAVRAGHRAA
MEALQALLQPRRSA

Sequences:

>Translated_494_residues
MSADLDQLSTQSRQRRLLLQAIGGAALAGGLGVTGRAMAQIEPVDTSILDVVIIGAGLSGLTSARDLQAAGCESFAVLEA
RDRVGGRTLNHDLGNGVISEAGGQWIGPGQTSIADLARQLDVATFPTYYKGKAVYLMDEVNIQEDLSDGPNSNTEVVAKL
NKLAEGVPSKAPWKAKDAAELDKLSVGQWLAGQGISNVDKIGFNMSVSLTFGTTPAGMGLLHYLAMINSSDCRLEKLEGL
QGGAQESRLAGGSQILSLKMAQALGDKIRLACPVRKIVGWDRDVVELHTDQGIIRTRQVIAALSPALCNQILFDPPLPSG
RAELQRHWPAHAPMRKTVHVYERPFWRDQGLNGQIVPVEGPLIWAFDNSPADGSLGVLSGFVRTGQLPHDPKTAQDILSA
IYASAMGEQALHPIQFHDLDWGKIDPWSLSCISPMPPGFWTQWGEYLTPAVGRLIWSGTETAEIWAGAMDGAVRAGHRAA
MEALQALLQPRRSA
>Mature_493_residues
SADLDQLSTQSRQRRLLLQAIGGAALAGGLGVTGRAMAQIEPVDTSILDVVIIGAGLSGLTSARDLQAAGCESFAVLEAR
DRVGGRTLNHDLGNGVISEAGGQWIGPGQTSIADLARQLDVATFPTYYKGKAVYLMDEVNIQEDLSDGPNSNTEVVAKLN
KLAEGVPSKAPWKAKDAAELDKLSVGQWLAGQGISNVDKIGFNMSVSLTFGTTPAGMGLLHYLAMINSSDCRLEKLEGLQ
GGAQESRLAGGSQILSLKMAQALGDKIRLACPVRKIVGWDRDVVELHTDQGIIRTRQVIAALSPALCNQILFDPPLPSGR
AELQRHWPAHAPMRKTVHVYERPFWRDQGLNGQIVPVEGPLIWAFDNSPADGSLGVLSGFVRTGQLPHDPKTAQDILSAI
YASAMGEQALHPIQFHDLDWGKIDPWSLSCISPMPPGFWTQWGEYLTPAVGRLIWSGTETAEIWAGAMDGAVRAGHRAAM
EALQALLQPRRSA

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=455, Percent_Identity=29.010989010989, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI38202207, Length=450, Percent_Identity=28.4444444444444, Blast_Score=178, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 52922; Mature: 52791

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADLDQLSTQSRQRRLLLQAIGGAALAGGLGVTGRAMAQIEPVDTSILDVVIIGAGLSG
CCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCC
LTSARDLQAAGCESFAVLEARDRVGGRTLNHDLGNGVISEAGGQWIGPGQTSIADLARQL
CCCHHHHHHCCCCCEEEEEHHHHCCCCEECCHHCCCHHHHCCCCCCCCCCHHHHHHHHHH
DVATFPTYYKGKAVYLMDEVNIQEDLSDGPNSNTEVVAKLNKLAEGVPSKAPWKAKDAAE
CHHCCCCEECCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LDKLSVGQWLAGQGISNVDKIGFNMSVSLTFGTTPAGMGLLHYLAMINSSDCRLEKLEGL
HHHHHHCCHHHCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHCC
QGGAQESRLAGGSQILSLKMAQALGDKIRLACPVRKIVGWDRDVVELHTDQGIIRTRQVI
CCCCHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEECCCCHHHHHHHH
AALSPALCNQILFDPPLPSGRAELQRHWPAHAPMRKTVHVYERPFWRDQGLNGQIVPVEG
HHHCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECC
PLIWAFDNSPADGSLGVLSGFVRTGQLPHDPKTAQDILSAIYASAMGEQALHPIQFHDLD
CEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCC
WGKIDPWSLSCISPMPPGFWTQWGEYLTPAVGRLIWSGTETAEIWAGAMDGAVRAGHRAA
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MEALQALLQPRRSA
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SADLDQLSTQSRQRRLLLQAIGGAALAGGLGVTGRAMAQIEPVDTSILDVVIIGAGLSG
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCC
LTSARDLQAAGCESFAVLEARDRVGGRTLNHDLGNGVISEAGGQWIGPGQTSIADLARQL
CCCHHHHHHCCCCCEEEEEHHHHCCCCEECCHHCCCHHHHCCCCCCCCCCHHHHHHHHHH
DVATFPTYYKGKAVYLMDEVNIQEDLSDGPNSNTEVVAKLNKLAEGVPSKAPWKAKDAAE
CHHCCCCEECCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LDKLSVGQWLAGQGISNVDKIGFNMSVSLTFGTTPAGMGLLHYLAMINSSDCRLEKLEGL
HHHHHHCCHHHCCCCCCHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHCC
QGGAQESRLAGGSQILSLKMAQALGDKIRLACPVRKIVGWDRDVVELHTDQGIIRTRQVI
CCCCHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEECCCCHHHHHHHH
AALSPALCNQILFDPPLPSGRAELQRHWPAHAPMRKTVHVYERPFWRDQGLNGQIVPVEG
HHHCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECC
PLIWAFDNSPADGSLGVLSGFVRTGQLPHDPKTAQDILSAIYASAMGEQALHPIQFHDLD
CEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCC
WGKIDPWSLSCISPMPPGFWTQWGEYLTPAVGRLIWSGTETAEIWAGAMDGAVRAGHRAA
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MEALQALLQPRRSA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]