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The map label for this gene is guaD [H]

Identifier: 77458955

GI number: 77458955

Start: 3147214

End: 3147723

Strand: Direct

Name: guaD [H]

Synonym: Pfl01_2730

Alternate gene names: 77458955

Gene position: 3147214-3147723 (Clockwise)

Preceding gene: 77458954

Following gene: 77458956

Centisome position: 48.88

GC content: 62.35

Gene sequence:

>510_bases
ATGAATCAATTGACTGAACTCATCCCGGCTGGCATCAGCGCGCTTGATCTGACGTTACTGCGCCAGACCATTGCCTTGTC
CGAGGCATCGAAGCAACGCGGTCGCCATCCGTTCGCGGCATTGGTGGCCGACCGCAACGGCAAGGTGATTGTCGAAGCGG
GGAACAACTCGATGCCCCCGGAAGGTGATCCAACCCAGCATGCCGAGTTGGTGGCAGCGGCGGCAGCGGCAAAACTCCTG
TCGCCGCAGGAGTTGGAACTGTGCACGCTGTACACCAGCGCCGAGCCATGCTGCATGTGCGCCGGCGCGGTGTATTGGAC
GGGGATCGGACGTGTGGTCTATGCCTTGTCGGAGCATGCCTTGCTGGGACTGACGGGGGACCATCCGGAGAATCCGACGT
TCTCGCTGCCGTGCCGCGAGGTGTTCGCCAAGGGGCAACGTAAGGTCAGTGTGTTGGGGCCGATGCTGGAGGGGGAGGCG
GCTGAACCGCACAGGGGGTTTTGGTCGTAA

Upstream 100 bases:

>100_bases
CGTTCTGCTCAACGATGAAAAAAAACCGACCGAAACCATCGGCGCTACATCGGCTGAACTGGCCGACTGACTTTTGTTTT
CCACTGCCCTGGAGTTACCC

Downstream 100 bases:

>100_bases
CAGGTTTTGAAACGAAGCTCGAGTGATGTGATGTCGCGCACTCGCATGCGACGTCTGCAATAATGACGCCCCACTGAGAC
GCGAAGGCATCAAGTGCTCG

Product: cytidine/deoxycytidylate deaminase zinc-binding subunit

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MNQLTELIPAGISALDLTLLRQTIALSEASKQRGRHPFAALVADRNGKVIVEAGNNSMPPEGDPTQHAELVAAAAAAKLL
SPQELELCTLYTSAEPCCMCAGAVYWTGIGRVVYALSEHALLGLTGDHPENPTFSLPCREVFAKGQRKVSVLGPMLEGEA
AEPHRGFWS

Sequences:

>Translated_169_residues
MNQLTELIPAGISALDLTLLRQTIALSEASKQRGRHPFAALVADRNGKVIVEAGNNSMPPEGDPTQHAELVAAAAAAKLL
SPQELELCTLYTSAEPCCMCAGAVYWTGIGRVVYALSEHALLGLTGDHPENPTFSLPCREVFAKGQRKVSVLGPMLEGEA
AEPHRGFWS
>Mature_169_residues
MNQLTELIPAGISALDLTLLRQTIALSEASKQRGRHPFAALVADRNGKVIVEAGNNSMPPEGDPTQHAELVAAAAAAKLL
SPQELELCTLYTSAEPCCMCAGAVYWTGIGRVVYALSEHALLGLTGDHPENPTFSLPCREVFAKGQRKVSVLGPMLEGEA
AEPHRGFWS

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 18006; Mature: 18006

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLTELIPAGISALDLTLLRQTIALSEASKQRGRHPFAALVADRNGKVIVEAGNNSMPP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCC
EGDPTQHAELVAAAAAAKLLSPQELELCTLYTSAEPCCMCAGAVYWTGIGRVVYALSEHA
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LLGLTGDHPENPTFSLPCREVFAKGQRKVSVLGPMLEGEAAEPHRGFWS
EEEECCCCCCCCCEECCHHHHHHCCCCEEEHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQLTELIPAGISALDLTLLRQTIALSEASKQRGRHPFAALVADRNGKVIVEAGNNSMPP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCC
EGDPTQHAELVAAAAAAKLLSPQELELCTLYTSAEPCCMCAGAVYWTGIGRVVYALSEHA
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LLGLTGDHPENPTFSLPCREVFAKGQRKVSVLGPMLEGEAAEPHRGFWS
EEEECCCCCCCCCEECCHHHHHHCCCCEEEHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]