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The map label for this gene is selA [H]

Identifier: 77458931

GI number: 77458931

Start: 3115774

End: 3117180

Strand: Direct

Name: selA [H]

Synonym: Pfl01_2706

Alternate gene names: 77458931

Gene position: 3115774-3117180 (Clockwise)

Preceding gene: 77458930

Following gene: 77458932

Centisome position: 48.39

GC content: 66.03

Gene sequence:

>1407_bases
ATGTCCGTGAGTGTTGCCCTGCGGTTACCGTCGATTGACAGCCTGTTACGCCACCCCGCGTGCCAGCCATTGGCCGAGCG
TTACGGACGCGAGGCGCTGTTGACGGGGTTTCGCCAGTTACTGGATGACTTGCGCGAAGCGGTGGTGGCGGGGCAACTGA
CCGCCGTTGAAATCAGCCCTGAAGCGCTGGCCGGAAGAGTTGCCGAACGTCTGGCATTGAAGCAGCGCAGCCAGGTGCGC
CGGGTGTTCAACCTGACCGGCACCGTGCTGCACACCAACCTCGGCCGGGCTTTGTTGCCCGAAGAAGCCATTGACGCCGT
GCAACTGGCGGCGCGCTATCCCTTGAACCTGGAATTCGATCTGGCCAGCGGCAAGCGCGGTGACCGCGACGACTTGATCG
AAGGCCTGATCCGCGAGCTGACCGGCGCCGAAGCCGTGACCGTGGTCAACAACAATGCCGCCGCCGTGCTGCTGACGCTC
AACAGCCTCGGCGCTCGCAAGGAAGGCATCATTTCCCGGGGCGAGCTGATCGAGATCGGCGGCGCGTTTCGCATTCCCGA
CATCATGAGCCGCGCCGGCGTGCGCCTGCACGAGGTCGGCACCACCAATCGCACCCATGCCCGCGACTACGAGGCGGCAA
TCAGCCCACGCAGCGGCCTGATCATGCGCGTGCACGCGAGCAACTACAGCATCGAAGGCTTCACCGCCCGGGTGCCGACC
TCCGAACTGGCGGCGTTGGCCCATCGGCATGACCTGCCGCTGCTGGAAGATCTTGGGAGCGGCAGTCTGCTGGACCTGAC
CCGCTGGGGTTTGCCGGCGGAACCGACGGTGCGTCAAGCGTTGCTTGATGGCGCCGACATCGTCACCTTCAGCGGCGACA
AACTGCTTGGCGGGCCGCAGGCGGGGGTGATCGTCGGGCGCAAGGACCTGATCGCGAAGATCAAGAAGAACCCGCTGAAA
CGCGCGTTGCGGGTCGACAAACTGACGCTGGCCGCACTCGAAGCGGTACTCGGGCTCTATCGCGACCCGGATCGTCTGGC
CGAGCGTTTGCCGAGCCTGCGCCTGTTGACCCGACCGCAAGCCGACATTCTGGCCCAGGCCGAACGCCTGCAACCGGCCT
TGGCCGAACTGCTGGGCGAGGGCTGGATCGTCACGGCGCAGCCAGCGCTGGGCATGATCGGTAGCGGCAGCCAACCGGTG
GCGCGCCTGCCGAGCGCAGCGCTGTGTCTGCGCCCACAGGTATCGAAACGCCTGCGCGGACGTTGCCTGTTGAATCTGGA
AGCCGCGCTGCGCGCCTTGCCGATCCCGGTGCTCGGGCGCATCGATGACGACGCGCTGTGGCTGGATCTGCGGCAGCTCG
ACGATGAACCGGCGTGGCTGGCGCAACTCGGGCAGTTGCAAACGTGA

Upstream 100 bases:

>100_bases
GGACTTGAGTCAAACCTATGTGCCGATTCAGCGGGCCGCGCTGCGCTAGAAGCAGGGTGGTCTAACATCATCAGGCGTAG
TTCGATTTCGGGAGTGCCTG

Downstream 100 bases:

>100_bases
TCGTCGGCACGGCAGGGCACATCGACCACGGCAAGACGTCACTGCTGCAAGCGCTGACCGGGCAAACCGGCGACCGCCGC
CCGCAGGAACGTGAGCGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSVSVALRLPSIDSLLRHPACQPLAERYGREALLTGFRQLLDDLREAVVAGQLTAVEISPEALAGRVAERLALKQRSQVR
RVFNLTGTVLHTNLGRALLPEEAIDAVQLAARYPLNLEFDLASGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLTL
NSLGARKEGIISRGELIEIGGAFRIPDIMSRAGVRLHEVGTTNRTHARDYEAAISPRSGLIMRVHASNYSIEGFTARVPT
SELAALAHRHDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALLDGADIVTFSGDKLLGGPQAGVIVGRKDLIAKIKKNPLK
RALRVDKLTLAALEAVLGLYRDPDRLAERLPSLRLLTRPQADILAQAERLQPALAELLGEGWIVTAQPALGMIGSGSQPV
ARLPSAALCLRPQVSKRLRGRCLLNLEAALRALPIPVLGRIDDDALWLDLRQLDDEPAWLAQLGQLQT

Sequences:

>Translated_468_residues
MSVSVALRLPSIDSLLRHPACQPLAERYGREALLTGFRQLLDDLREAVVAGQLTAVEISPEALAGRVAERLALKQRSQVR
RVFNLTGTVLHTNLGRALLPEEAIDAVQLAARYPLNLEFDLASGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLTL
NSLGARKEGIISRGELIEIGGAFRIPDIMSRAGVRLHEVGTTNRTHARDYEAAISPRSGLIMRVHASNYSIEGFTARVPT
SELAALAHRHDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALLDGADIVTFSGDKLLGGPQAGVIVGRKDLIAKIKKNPLK
RALRVDKLTLAALEAVLGLYRDPDRLAERLPSLRLLTRPQADILAQAERLQPALAELLGEGWIVTAQPALGMIGSGSQPV
ARLPSAALCLRPQVSKRLRGRCLLNLEAALRALPIPVLGRIDDDALWLDLRQLDDEPAWLAQLGQLQT
>Mature_467_residues
SVSVALRLPSIDSLLRHPACQPLAERYGREALLTGFRQLLDDLREAVVAGQLTAVEISPEALAGRVAERLALKQRSQVRR
VFNLTGTVLHTNLGRALLPEEAIDAVQLAARYPLNLEFDLASGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLTLN
SLGARKEGIISRGELIEIGGAFRIPDIMSRAGVRLHEVGTTNRTHARDYEAAISPRSGLIMRVHASNYSIEGFTARVPTS
ELAALAHRHDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALLDGADIVTFSGDKLLGGPQAGVIVGRKDLIAKIKKNPLKR
ALRVDKLTLAALEAVLGLYRDPDRLAERLPSLRLLTRPQADILAQAERLQPALAELLGEGWIVTAQPALGMIGSGSQPVA
RLPSAALCLRPQVSKRLRGRCLLNLEAALRALPIPVLGRIDDDALWLDLRQLDDEPAWLAQLGQLQT

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=460, Percent_Identity=52.6086956521739, Blast_Score=417, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50663; Mature: 50532

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSVALRLPSIDSLLRHPACQPLAERYGREALLTGFRQLLDDLREAVVAGQLTAVEISP
CCEEEEEECCCHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECH
EALAGRVAERLALKQRSQVRRVFNLTGTVLHTNLGRALLPEEAIDAVQLAARYPLNLEFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHCCCCCEEEE
LASGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLTLNSLGARKEGIISRGELIEIG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCHHCCCCCCCEEEEC
GAFRIPDIMSRAGVRLHEVGTTNRTHARDYEAAISPRSGLIMRVHASNYSIEGFTARVPT
CCCCCHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEECCEEEECCH
SELAALAHRHDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALLDGADIVTFSGDKLLGGPQ
HHHHHHHHHCCCCHHHHCCCCCEEEHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCC
AGVIVGRKDLIAKIKKNPLKRALRVDKLTLAALEAVLGLYRDPDRLAERLPSLRLLTRPQ
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECCCC
ADILAQAERLQPALAELLGEGWIVTAQPALGMIGSGSQPVARLPSAALCLRPQVSKRLRG
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHCCCHHHHCCHHHHHHHCC
RCLLNLEAALRALPIPVLGRIDDDALWLDLRQLDDEPAWLAQLGQLQT
EEEEEHHHHHHHCCCCCCCCCCCCHHEEEHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SVSVALRLPSIDSLLRHPACQPLAERYGREALLTGFRQLLDDLREAVVAGQLTAVEISP
CEEEEEECCCHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECH
EALAGRVAERLALKQRSQVRRVFNLTGTVLHTNLGRALLPEEAIDAVQLAARYPLNLEFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHCCCCCEEEE
LASGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLTLNSLGARKEGIISRGELIEIG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCHHCCCCCCCEEEEC
GAFRIPDIMSRAGVRLHEVGTTNRTHARDYEAAISPRSGLIMRVHASNYSIEGFTARVPT
CCCCCHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEECCEEEECCH
SELAALAHRHDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALLDGADIVTFSGDKLLGGPQ
HHHHHHHHHCCCCHHHHCCCCCEEEHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCC
AGVIVGRKDLIAKIKKNPLKRALRVDKLTLAALEAVLGLYRDPDRLAERLPSLRLLTRPQ
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECCCC
ADILAQAERLQPALAELLGEGWIVTAQPALGMIGSGSQPVARLPSAALCLRPQVSKRLRG
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHCCCHHHHCCHHHHHHHCC
RCLLNLEAALRALPIPVLGRIDDDALWLDLRQLDDEPAWLAQLGQLQT
EEEEEHHHHHHHCCCCCCCCCCCCHHEEEHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA