Click here to switch to the map view.

The map label for this gene is aprE [H]

Identifier: 77458906

GI number: 77458906

Start: 3082244

End: 3083593

Strand: Direct

Name: aprE [H]

Synonym: Pfl01_2681

Alternate gene names: 77458906

Gene position: 3082244-3083593 (Clockwise)

Preceding gene: 77458905

Following gene: 77458907

Centisome position: 47.87

GC content: 63.26

Gene sequence:

>1350_bases
ATGAGCAGCGCGAGCATGAACACGCAAAACGAAGCCACGATGGAAAACGACTACATCACCGAACGCCCGGAGCGCGATGC
GAAGTTCTTCGCCCGCATGGGCTGGATTCTGGCGCTGGTCGGTGCCGGCAGTTTCTTTACCTGGGCGGCATTGGCGCCGC
TGGATCAAGGCATTCCGGTGCAAGGCACGGTGGTGGTGTCGGGCAAGCGCAAGGCCGTGCAGTCGATGAGCAGCGGCGTG
GTCAGCCGGATTCTGGTGCGCGAAGGCGAAATCGTGAAGCAGGGCCAGCCGCTGTTCCGCCTCGACCAGACTCAGGTCGC
CGCCGACGTGCAGTCGTTGCAGGCGCAATACCGCATGGCCTGGGCCAGCCTGGCGCGCTGGCAGGCCGAGCGTGACAACC
TCAAGCAAGTGACCTTTCCGGCAGAACTGAGCGATAACGCCGATCCGCGCCTGGCGCTGGTGCTGGAAGGCCAGCGGCAA
CTGTTCAGCAGCCGCCGTGAAGCGTTTTCCCGCGAGCAGGCCGCCCTGCGTGCCAGCATCGAAGGTGCCACTGCGCAACT
GGCGGGCATGCGCCGCGCCCGTACTGACCTCAACGCGCAGGCCGACTCGCTGCAACAGCAGTTGAGCAATCTGCAACCGC
TGGCCGACAACGGCTACATCCCGCGCAACCGCTTGATGGAATACCAGCGTCAGCTGTCGCAGGTTCAGCAGCAACTGGCC
GAGAACACGGGCGAAAGTGGCCGGGTAGAGCAGGGCATTCTCGAGTCCCGCCTGAAGCTGCAACAGCACGGCGAGGAGTA
CCAGAAGGAAGTCCGCACTCAACTGGCCGACGCGCAACTGAAAAGCGTCACGCTGTCGGAGCAACTCACCTCCGCCGGTT
TCGACCTGCAACACAGCGAAATCCTTGCCACCGCCGACGGCGTGGCAGTCAACCTCGGCGTACACACCGAAGGCGCCGTG
GTGCGTCAGGGCGAAACCCTGCTGGAAATCGTCCCGCAAGGCACGCGCCTGGAAGTCGAAGGCCACCTGCCGATCAACCT
GATCGACAAGGTCGGCACGCACTTGCCGGTCGACATCCTGTTCACCGCCTTCAACCAGAGCAAGACGCCACGGGTGCCCG
GCGAAGTCAGCCTGATTTCCGCCGACCAGATGGTCGACGAGAAAACCGGCGTGCCGTACTACGTGTTGCGCAGCAGCGTC
AGCGATCAGGCCATGGAAAAGCTCAATGGCCTGGTGATCAAACCCGGCATGCCGGCGGAAATGTTCGTGCGCACTGGCGA
ACGTTCACTCCTCAACTACCTGTTCAAGCCGCTGCTCGACCGCGCCGGTTCCGCGTTGACCGAAGAATAA

Upstream 100 bases:

>100_bases
AGCCCGGCAACCAGCCACAACAAAATGAAAAACCTGCGCAAGCACCGGCCGGGCTCAGCATGAGCCGCCAGTATCAGCCG
ACGACAAGGAATTCGGGTGT

Downstream 100 bases:

>100_bases
GGATGTTCGGCTGTATGAATAAGCTTTCCATGCTGGCTGCAGCGCTCGCGCTGCTTGCGGGCAACAGTGCAGTGGCGGCC
ATGGGGCCGTTCGAGATCTA

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSSASMNTQNEATMENDYITERPERDAKFFARMGWILALVGAGSFFTWAALAPLDQGIPVQGTVVVSGKRKAVQSMSSGV
VSRILVREGEIVKQGQPLFRLDQTQVAADVQSLQAQYRMAWASLARWQAERDNLKQVTFPAELSDNADPRLALVLEGQRQ
LFSSRREAFSREQAALRASIEGATAQLAGMRRARTDLNAQADSLQQQLSNLQPLADNGYIPRNRLMEYQRQLSQVQQQLA
ENTGESGRVEQGILESRLKLQQHGEEYQKEVRTQLADAQLKSVTLSEQLTSAGFDLQHSEILATADGVAVNLGVHTEGAV
VRQGETLLEIVPQGTRLEVEGHLPINLIDKVGTHLPVDILFTAFNQSKTPRVPGEVSLISADQMVDEKTGVPYYVLRSSV
SDQAMEKLNGLVIKPGMPAEMFVRTGERSLLNYLFKPLLDRAGSALTEE

Sequences:

>Translated_449_residues
MSSASMNTQNEATMENDYITERPERDAKFFARMGWILALVGAGSFFTWAALAPLDQGIPVQGTVVVSGKRKAVQSMSSGV
VSRILVREGEIVKQGQPLFRLDQTQVAADVQSLQAQYRMAWASLARWQAERDNLKQVTFPAELSDNADPRLALVLEGQRQ
LFSSRREAFSREQAALRASIEGATAQLAGMRRARTDLNAQADSLQQQLSNLQPLADNGYIPRNRLMEYQRQLSQVQQQLA
ENTGESGRVEQGILESRLKLQQHGEEYQKEVRTQLADAQLKSVTLSEQLTSAGFDLQHSEILATADGVAVNLGVHTEGAV
VRQGETLLEIVPQGTRLEVEGHLPINLIDKVGTHLPVDILFTAFNQSKTPRVPGEVSLISADQMVDEKTGVPYYVLRSSV
SDQAMEKLNGLVIKPGMPAEMFVRTGERSLLNYLFKPLLDRAGSALTEE
>Mature_448_residues
SSASMNTQNEATMENDYITERPERDAKFFARMGWILALVGAGSFFTWAALAPLDQGIPVQGTVVVSGKRKAVQSMSSGVV
SRILVREGEIVKQGQPLFRLDQTQVAADVQSLQAQYRMAWASLARWQAERDNLKQVTFPAELSDNADPRLALVLEGQRQL
FSSRREAFSREQAALRASIEGATAQLAGMRRARTDLNAQADSLQQQLSNLQPLADNGYIPRNRLMEYQRQLSQVQQQLAE
NTGESGRVEQGILESRLKLQQHGEEYQKEVRTQLADAQLKSVTLSEQLTSAGFDLQHSEILATADGVAVNLGVHTEGAVV
RQGETLLEIVPQGTRLEVEGHLPINLIDKVGTHLPVDILFTAFNQSKTPRVPGEVSLISADQMVDEKTGVPYYVLRSSVS
DQAMEKLNGLVIKPGMPAEMFVRTGERSLLNYLFKPLLDRAGSALTEE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49560; Mature: 49429

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASMNTQNEATMENDYITERPERDAKFFARMGWILALVGAGSFFTWAALAPLDQGIPV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
QGTVVVSGKRKAVQSMSSGVVSRILVREGEIVKQGQPLFRLDQTQVAADVQSLQAQYRMA
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECHHHHHHHHHHHHHHHHHH
WASLARWQAERDNLKQVTFPAELSDNADPRLALVLEGQRQLFSSRREAFSREQAALRASI
HHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
EGATAQLAGMRRARTDLNAQADSLQQQLSNLQPLADNGYIPRNRLMEYQRQLSQVQQQLA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENTGESGRVEQGILESRLKLQQHGEEYQKEVRTQLADAQLKSVTLSEQLTSAGFDLQHSE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ILATADGVAVNLGVHTEGAVVRQGETLLEIVPQGTRLEVEGHLPINLIDKVGTHLPVDIL
HEEECCCEEEEEEECCCCCEEECCCHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHH
FTAFNQSKTPRVPGEVSLISADQMVDEKTGVPYYVLRSSVSDQAMEKLNGLVIKPGMPAE
HHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHCHHHHHHHHHCCEEECCCCCHH
MFVRTGERSLLNYLFKPLLDRAGSALTEE
HHHHCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSASMNTQNEATMENDYITERPERDAKFFARMGWILALVGAGSFFTWAALAPLDQGIPV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
QGTVVVSGKRKAVQSMSSGVVSRILVREGEIVKQGQPLFRLDQTQVAADVQSLQAQYRMA
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECHHHHHHHHHHHHHHHHHH
WASLARWQAERDNLKQVTFPAELSDNADPRLALVLEGQRQLFSSRREAFSREQAALRASI
HHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
EGATAQLAGMRRARTDLNAQADSLQQQLSNLQPLADNGYIPRNRLMEYQRQLSQVQQQLA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENTGESGRVEQGILESRLKLQQHGEEYQKEVRTQLADAQLKSVTLSEQLTSAGFDLQHSE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ILATADGVAVNLGVHTEGAVVRQGETLLEIVPQGTRLEVEGHLPINLIDKVGTHLPVDIL
HEEECCCEEEEEEECCCCCEEECCCHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHH
FTAFNQSKTPRVPGEVSLISADQMVDEKTGVPYYVLRSSVSDQAMEKLNGLVIKPGMPAE
HHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHCHHHHHHHHHCCEEECCCCCHH
MFVRTGERSLLNYLFKPLLDRAGSALTEE
HHHHCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]