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The map label for this gene is aaeB [H]

Identifier: 77458880

GI number: 77458880

Start: 3043650

End: 3045785

Strand: Direct

Name: aaeB [H]

Synonym: Pfl01_2655

Alternate gene names: 77458880

Gene position: 3043650-3045785 (Clockwise)

Preceding gene: 77458875

Following gene: 77458881

Centisome position: 47.27

GC content: 60.91

Gene sequence:

>2136_bases
ATGCAATCCCTGCTTATTTATTTCAAGGCGGTGATCCACCCCAGCCAGGCAGTGCTGCTGTTTGGTTTGCGCACGATTGC
CGCCGGATTGCTGACGTTGTACCTGGCGTTCCTGTTCGATCTGGACCAGCCGAAGTGGTCGATCATGGCCGTGGTGATCA
TCAGCCAGCCCTTGGCCGGGATGGCGCTGGCTCGCAGCTTCGGACAAATCATCGGAACGACCCTCGGCGCGATGGTGGCG
GTGCTGCTGATGGCGATCTTTCCCCAGGCACCGTTGCCATTCATCACGACCCTGGCGCTGTGGCTGGCCCTGTGCACGGC
CGGCGGCACGTTATTGCGCTACACCAGTTCCCAGGCGTTCGTGCTCAGCGGGTACACCGCCGTAGTGGTGGCGCTGCTGG
CGATTCCGGATCAGGACGGCACCTTTTTGCTGGCGGTGACCCGGGTCACCGAAACCTTGCTGGCGGTGGCATGCGTTTGC
GTGGTCAGCCTGCTGACGGCTCGGCCGGAGGCGGTATCGCGCAACTATTTCGCGAAGGTCGATCAGGTGATCAGACTGGT
CGCCAGCCATTCAGCCGCGGTGCTTCGAACCGAAGAAAGCGAAGCGGACTTTCAGCGCCGGCAAATGCAGCTGCTGGGGG
AAATCAGCGCTCTTGAAGGGCTGCGCCGGCACTTGTATTTCGATGCTCCGCGTCTGCGCAGCGCCAACAATCTGGTTTTG
TTACTCGGCAATCAACTGATGCTGCTGACTTCGCGCCTCACCGCGTTGCGTCACCAGCGGGAATTGCTTACCGAGCGCTG
GGAGGGCGATCTGCCGCTGGACATCCAGCAATTGCGCGCCGAGGAGCTGGCACTTCTTGATCAGCTCGCACAGCAAGGGC
GATCATTGCCGGCCGAGGTGCGGCACCAGTTCGTCGCGCTGCAACAGCAATTCGAAGCGCTGGCCTACAAGGCCGAACAA
CTGACGGAAGACATGAGCGCAACCCTGCGCTCGCTGGCCTGGGCGCTGCGCTGGGAACAGGCGCGGCTGTTGCAGCAGCT
GGAGCAGATTCTCGAACTGAGCGACGCGATACAGGAAGGGCGGGAGGCCAGCTGCATGTTCCGTGGCCAGTCCAGCCCCT
TGCACCTGGATTTCACCCTCGCAACGATGAACGCCATTCGCGCCTTCAGCGCGTTGCTGGTAGCCGGGCTGATCTGGATC
GAAACCGCGTGGGACGGCGCGCGGGGCGGGATGATTCTGGTGGGGATCCTGTGTTCGTTGATGGCGACGTTTCCGCGCCC
ATTGATCGCCGCGCAAAGTTACGCCCGAGGGCTGGGACTGGCCTTGGTGGTGTCGGCCTTCTATCAGTTCATGCTGGTTC
CGGCGATCAGTGATTTCGAGATGCTGGCCTTGCTGCTTGCGCCTTTGCTGTATGTGATCGCAGTCGGACTGTCCAGCCCG
GCCACCGCCGGTATCGGCATGGGACTGGGGCTGTCGAGTTTCCTGATGCTGGGACCGCAGAACGTCGGCACCGGACAGAA
CACCGCCATTCAATGGTTCGAATTTGCCGGCGCCTACGTCAGTGCGGCGATACTGGCTCTGATCGTCTACGCCTGGATCT
TCCCGTTCCGCCCGGCCTTTCGAATCAGGCGCTTTTATAACGAGGCGCGGGAGCAGGTCTATCAACTGACAAAAAGCCCG
GCTACCGACGAACAGCAATTCGCCTTCGAAAGTCGCATGGTCGATCGCCTGACCTCGATGCTGGGGGTGTTGCCAGCCGC
CAATGATCGGGACATGCAGCGTTTGTATGAAATCAGTCTCGCCTGTGTAGCGCTGGGCGTGGCCATGCACCAGCTCAGGC
AACAGGCACAGAACAATACTCTGCTCACTGACGCATTCGTTCGGCAGCTGTCGACGGCATTGCGTCAGACCGGTCGTTTT
GTCGCCGGCCGACCAGATGTGCGCCTGACACCGTTACTGACTACGCTGCAAGCGCTCGGCGATGATCTGGATGCCTTGCA
TGTCGCCACCCATGAGCACTTGTGGTCGGTCTTTCGCATGCGTGTGGCCCTGTTGATCGTGGTGTCGTTTCTGGAACGAC
ATGGCGAGCATTTGCAGCCCGACAATTCTGAAGGAGAGCCCGTCCTTGCCCATTGA

Upstream 100 bases:

>100_bases
ACAGGCGTTGAATCGACCTACAGCTTGTGTCGACCCTGTTTGCCGTCATGCCCTCCATGCAGTGTCTACGCTTGCAGAAG
TTGTTTCGAAGAGGCTACCC

Downstream 100 bases:

>100_bases
TTTCGAGATTGGCGGCGTCTACCTGCCTCCCATTGCCCAGGCCCTGTTAATGGCCATACCGGTTTTTCTGGTGCTCGACT
GGGGTTTGCGCCGGCTTGGC

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MQSLLIYFKAVIHPSQAVLLFGLRTIAAGLLTLYLAFLFDLDQPKWSIMAVVIISQPLAGMALARSFGQIIGTTLGAMVA
VLLMAIFPQAPLPFITTLALWLALCTAGGTLLRYTSSQAFVLSGYTAVVVALLAIPDQDGTFLLAVTRVTETLLAVACVC
VVSLLTARPEAVSRNYFAKVDQVIRLVASHSAAVLRTEESEADFQRRQMQLLGEISALEGLRRHLYFDAPRLRSANNLVL
LLGNQLMLLTSRLTALRHQRELLTERWEGDLPLDIQQLRAEELALLDQLAQQGRSLPAEVRHQFVALQQQFEALAYKAEQ
LTEDMSATLRSLAWALRWEQARLLQQLEQILELSDAIQEGREASCMFRGQSSPLHLDFTLATMNAIRAFSALLVAGLIWI
ETAWDGARGGMILVGILCSLMATFPRPLIAAQSYARGLGLALVVSAFYQFMLVPAISDFEMLALLLAPLLYVIAVGLSSP
ATAGIGMGLGLSSFLMLGPQNVGTGQNTAIQWFEFAGAYVSAAILALIVYAWIFPFRPAFRIRRFYNEAREQVYQLTKSP
ATDEQQFAFESRMVDRLTSMLGVLPAANDRDMQRLYEISLACVALGVAMHQLRQQAQNNTLLTDAFVRQLSTALRQTGRF
VAGRPDVRLTPLLTTLQALGDDLDALHVATHEHLWSVFRMRVALLIVVSFLERHGEHLQPDNSEGEPVLAH

Sequences:

>Translated_711_residues
MQSLLIYFKAVIHPSQAVLLFGLRTIAAGLLTLYLAFLFDLDQPKWSIMAVVIISQPLAGMALARSFGQIIGTTLGAMVA
VLLMAIFPQAPLPFITTLALWLALCTAGGTLLRYTSSQAFVLSGYTAVVVALLAIPDQDGTFLLAVTRVTETLLAVACVC
VVSLLTARPEAVSRNYFAKVDQVIRLVASHSAAVLRTEESEADFQRRQMQLLGEISALEGLRRHLYFDAPRLRSANNLVL
LLGNQLMLLTSRLTALRHQRELLTERWEGDLPLDIQQLRAEELALLDQLAQQGRSLPAEVRHQFVALQQQFEALAYKAEQ
LTEDMSATLRSLAWALRWEQARLLQQLEQILELSDAIQEGREASCMFRGQSSPLHLDFTLATMNAIRAFSALLVAGLIWI
ETAWDGARGGMILVGILCSLMATFPRPLIAAQSYARGLGLALVVSAFYQFMLVPAISDFEMLALLLAPLLYVIAVGLSSP
ATAGIGMGLGLSSFLMLGPQNVGTGQNTAIQWFEFAGAYVSAAILALIVYAWIFPFRPAFRIRRFYNEAREQVYQLTKSP
ATDEQQFAFESRMVDRLTSMLGVLPAANDRDMQRLYEISLACVALGVAMHQLRQQAQNNTLLTDAFVRQLSTALRQTGRF
VAGRPDVRLTPLLTTLQALGDDLDALHVATHEHLWSVFRMRVALLIVVSFLERHGEHLQPDNSEGEPVLAH
>Mature_711_residues
MQSLLIYFKAVIHPSQAVLLFGLRTIAAGLLTLYLAFLFDLDQPKWSIMAVVIISQPLAGMALARSFGQIIGTTLGAMVA
VLLMAIFPQAPLPFITTLALWLALCTAGGTLLRYTSSQAFVLSGYTAVVVALLAIPDQDGTFLLAVTRVTETLLAVACVC
VVSLLTARPEAVSRNYFAKVDQVIRLVASHSAAVLRTEESEADFQRRQMQLLGEISALEGLRRHLYFDAPRLRSANNLVL
LLGNQLMLLTSRLTALRHQRELLTERWEGDLPLDIQQLRAEELALLDQLAQQGRSLPAEVRHQFVALQQQFEALAYKAEQ
LTEDMSATLRSLAWALRWEQARLLQQLEQILELSDAIQEGREASCMFRGQSSPLHLDFTLATMNAIRAFSALLVAGLIWI
ETAWDGARGGMILVGILCSLMATFPRPLIAAQSYARGLGLALVVSAFYQFMLVPAISDFEMLALLLAPLLYVIAVGLSSP
ATAGIGMGLGLSSFLMLGPQNVGTGQNTAIQWFEFAGAYVSAAILALIVYAWIFPFRPAFRIRRFYNEAREQVYQLTKSP
ATDEQQFAFESRMVDRLTSMLGVLPAANDRDMQRLYEISLACVALGVAMHQLRQQAQNNTLLTDAFVRQLSTALRQTGRF
VAGRPDVRLTPLLTTLQALGDDLDALHVATHEHLWSVFRMRVALLIVVSFLERHGEHLQPDNSEGEPVLAH

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=458, Percent_Identity=22.9257641921397, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787933, Length=580, Percent_Identity=23.7931034482759, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 78459; Mature: 78459

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLLIYFKAVIHPSQAVLLFGLRTIAAGLLTLYLAFLFDLDQPKWSIMAVVIISQPLAG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHCCHHH
MALARSFGQIIGTTLGAMVAVLLMAIFPQAPLPFITTLALWLALCTAGGTLLRYTSSQAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEE
VLSGYTAVVVALLAIPDQDGTFLLAVTRVTETLLAVACVCVVSLLTARPEAVSRNYFAKV
EECCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DQVIRLVASHSAAVLRTEESEADFQRRQMQLLGEISALEGLRRHLYFDAPRLRSANNLVL
HHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LLGNQLMLLTSRLTALRHQRELLTERWEGDLPLDIQQLRAEELALLDQLAQQGRSLPAEV
EECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
RHQFVALQQQFEALAYKAEQLTEDMSATLRSLAWALRWEQARLLQQLEQILELSDAIQEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
REASCMFRGQSSPLHLDFTLATMNAIRAFSALLVAGLIWIETAWDGARGGMILVGILCSL
CCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MATFPRPLIAAQSYARGLGLALVVSAFYQFMLVPAISDFEMLALLLAPLLYVIAVGLSSP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
ATAGIGMGLGLSSFLMLGPQNVGTGQNTAIQWFEFAGAYVSAAILALIVYAWIFPFRPAF
CCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIRRFYNEAREQVYQLTKSPATDEQQFAFESRMVDRLTSMLGVLPAANDRDMQRLYEISL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ACVALGVAMHQLRQQAQNNTLLTDAFVRQLSTALRQTGRFVAGRPDVRLTPLLTTLQALG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHC
DDLDALHVATHEHLWSVFRMRVALLIVVSFLERHGEHLQPDNSEGEPVLAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQSLLIYFKAVIHPSQAVLLFGLRTIAAGLLTLYLAFLFDLDQPKWSIMAVVIISQPLAG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHCCHHH
MALARSFGQIIGTTLGAMVAVLLMAIFPQAPLPFITTLALWLALCTAGGTLLRYTSSQAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEE
VLSGYTAVVVALLAIPDQDGTFLLAVTRVTETLLAVACVCVVSLLTARPEAVSRNYFAKV
EECCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DQVIRLVASHSAAVLRTEESEADFQRRQMQLLGEISALEGLRRHLYFDAPRLRSANNLVL
HHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LLGNQLMLLTSRLTALRHQRELLTERWEGDLPLDIQQLRAEELALLDQLAQQGRSLPAEV
EECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
RHQFVALQQQFEALAYKAEQLTEDMSATLRSLAWALRWEQARLLQQLEQILELSDAIQEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
REASCMFRGQSSPLHLDFTLATMNAIRAFSALLVAGLIWIETAWDGARGGMILVGILCSL
CCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MATFPRPLIAAQSYARGLGLALVVSAFYQFMLVPAISDFEMLALLLAPLLYVIAVGLSSP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
ATAGIGMGLGLSSFLMLGPQNVGTGQNTAIQWFEFAGAYVSAAILALIVYAWIFPFRPAF
CCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIRRFYNEAREQVYQLTKSPATDEQQFAFESRMVDRLTSMLGVLPAANDRDMQRLYEISL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ACVALGVAMHQLRQQAQNNTLLTDAFVRQLSTALRQTGRFVAGRPDVRLTPLLTTLQALG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHC
DDLDALHVATHEHLWSVFRMRVALLIVVSFLERHGEHLQPDNSEGEPVLAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA