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The map label for this gene is speB [H]

Identifier: 77458801

GI number: 77458801

Start: 2953591

End: 2954550

Strand: Direct

Name: speB [H]

Synonym: Pfl01_2576

Alternate gene names: 77458801

Gene position: 2953591-2954550 (Clockwise)

Preceding gene: 77458800

Following gene: 77458802

Centisome position: 45.87

GC content: 66.25

Gene sequence:

>960_bases
ATGGACGTGCCCATGCAAAACGATCAGGCCCTGACCCGTGACAGCCTTTTTGGCACCGCTGCTGAAAGCACCTACGCCGG
GATCACCAGTTTCATGCGCCGGCGCTACAGCCGCGACCTGCGCGGCGCGGACGTGGCGGTCAGCGGTGTGCCGTTCGACA
CCGCCACCAGCAACCGTCCGGGCGCCCGTTTCGGGCCGCGCGGGATTCGTGCGGCGTCCACCGGGATTGCCTGGGAACGG
CACTGGCCATGGGCGTTCGACCCGTTCGATCATCTGGCGGTGATCGACTACGGCGATTGCGACTTCGATTACGGCTCGCC
GCACACCATCCCGGACAGCATCGAGGCCCACGCCGAGCATATTCTCAGCTCCGGCAGCGCCATGCTCACCTTTGGCGGCG
ACCATTTCATCAGCTATCCGCTGCTCAAGGCCCATGCACGCAAGCACGGCACGCTGTCGCTGATCCACTTCGATGCGCAC
AGCGATACCTGGCCGGACGAGGGTGGCAAGCGGGTCGATCACGGCACCATGTTCTGGCACGCGGCGCGGGAAGGGCTGGT
GGATCCGGCGCGTTCGGTGCAGATCGGCTTGCGCACCACCAATGACGATCATCAGGGCTTTCAGGTGCTGGACGCGCGGC
AGGTGCATCGGTGTGGATGCGAGGCGATCATCGAGGCGATTCGCGCGCGGGTCGGGGATAACCCGGTGTACCTGACGTTC
GACATCGATTGCCTCGACCCGGCCTTCGCACCGGGCACCGGGACCCCGGTGTGCGGCGGGTTGAGCACGGTGCAGGCGCT
GGAGATCCTTGGCGGCCTGCGCGGGATCAATCTGGTGGGCATGGACGTGGTGGAAGTGGCCCCGGCTTACGACCACGCGG
ACGTGACGTCGCTGGCGGCGGCAACCCTGGCCATGGAGATGCTTTGCCTGTACGCGGCCCGGCACAAAGTCGACGCGTGA

Upstream 100 bases:

>100_bases
CCGACCGCAGCATGAGCCTCAAGGACATGCGCCAGCGCACGCGCTTGTGGACCACTTTCCGTAGCCGCCAATAGCCCTTC
ATCACAACAGGAACACACCA

Downstream 100 bases:

>100_bases
TCCCCTCCGAGTCTGGTGAAAGCTCCTGACAATTTCTGACACCAGGCTCTGCTAAGCTCCGGCAAATTTTTCTCCGGAGC
CTCACACCGTGTCGCGAACC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDVPMQNDQALTRDSLFGTAAESTYAGITSFMRRRYSRDLRGADVAVSGVPFDTATSNRPGARFGPRGIRAASTGIAWER
HWPWAFDPFDHLAVIDYGDCDFDYGSPHTIPDSIEAHAEHILSSGSAMLTFGGDHFISYPLLKAHARKHGTLSLIHFDAH
SDTWPDEGGKRVDHGTMFWHAAREGLVDPARSVQIGLRTTNDDHQGFQVLDARQVHRCGCEAIIEAIRARVGDNPVYLTF
DIDCLDPAFAPGTGTPVCGGLSTVQALEILGGLRGINLVGMDVVEVAPAYDHADVTSLAAATLAMEMLCLYAARHKVDA

Sequences:

>Translated_319_residues
MDVPMQNDQALTRDSLFGTAAESTYAGITSFMRRRYSRDLRGADVAVSGVPFDTATSNRPGARFGPRGIRAASTGIAWER
HWPWAFDPFDHLAVIDYGDCDFDYGSPHTIPDSIEAHAEHILSSGSAMLTFGGDHFISYPLLKAHARKHGTLSLIHFDAH
SDTWPDEGGKRVDHGTMFWHAAREGLVDPARSVQIGLRTTNDDHQGFQVLDARQVHRCGCEAIIEAIRARVGDNPVYLTF
DIDCLDPAFAPGTGTPVCGGLSTVQALEILGGLRGINLVGMDVVEVAPAYDHADVTSLAAATLAMEMLCLYAARHKVDA
>Mature_319_residues
MDVPMQNDQALTRDSLFGTAAESTYAGITSFMRRRYSRDLRGADVAVSGVPFDTATSNRPGARFGPRGIRAASTGIAWER
HWPWAFDPFDHLAVIDYGDCDFDYGSPHTIPDSIEAHAEHILSSGSAMLTFGGDHFISYPLLKAHARKHGTLSLIHFDAH
SDTWPDEGGKRVDHGTMFWHAAREGLVDPARSVQIGLRTTNDDHQGFQVLDARQVHRCGCEAIIEAIRARVGDNPVYLTF
DIDCLDPAFAPGTGTPVCGGLSTVQALEILGGLRGINLVGMDVVEVAPAYDHADVTSLAAATLAMEMLCLYAARHKVDA

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=44.3298969072165, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI10947139, Length=312, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4502215, Length=330, Percent_Identity=25.7575757575758, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789306, Length=273, Percent_Identity=54.9450549450549, Blast_Score=294, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34603; Mature: 34603

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVPMQNDQALTRDSLFGTAAESTYAGITSFMRRRYSRDLRGADVAVSGVPFDTATSNRP
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
GARFGPRGIRAASTGIAWERHWPWAFDPFDHLAVIDYGDCDFDYGSPHTIPDSIEAHAEH
CCCCCCCCCCHHHCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
ILSSGSAMLTFGGDHFISYPLLKAHARKHGTLSLIHFDAHSDTWPDEGGKRVDHGTMFWH
HHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
AAREGLVDPARSVQIGLRTTNDDHQGFQVLDARQVHRCGCEAIIEAIRARVGDNPVYLTF
HHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
DIDCLDPAFAPGTGTPVCGGLSTVQALEILGGLRGINLVGMDVVEVAPAYDHADVTSLAA
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCHHHHHHHH
ATLAMEMLCLYAARHKVDA
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDVPMQNDQALTRDSLFGTAAESTYAGITSFMRRRYSRDLRGADVAVSGVPFDTATSNRP
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
GARFGPRGIRAASTGIAWERHWPWAFDPFDHLAVIDYGDCDFDYGSPHTIPDSIEAHAEH
CCCCCCCCCCHHHCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
ILSSGSAMLTFGGDHFISYPLLKAHARKHGTLSLIHFDAHSDTWPDEGGKRVDHGTMFWH
HHHCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
AAREGLVDPARSVQIGLRTTNDDHQGFQVLDARQVHRCGCEAIIEAIRARVGDNPVYLTF
HHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
DIDCLDPAFAPGTGTPVCGGLSTVQALEILGGLRGINLVGMDVVEVAPAYDHADVTSLAA
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCHHHHHHHH
ATLAMEMLCLYAARHKVDA
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]