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The map label for this gene is fadL [H]

Identifier: 77458707

GI number: 77458707

Start: 2836861

End: 2838132

Strand: Direct

Name: fadL [H]

Synonym: Pfl01_2482

Alternate gene names: 77458707

Gene position: 2836861-2838132 (Clockwise)

Preceding gene: 77458706

Following gene: 77458709

Centisome position: 44.06

GC content: 59.2

Gene sequence:

>1272_bases
ATGAAAAAAATAATGCTCAAGAATCCCGTCGGCCTGGCGGTCGCGCTGGTGTCCTCCAATGTGTTGGCCGGTGGTTTTGC
CCTCAACGAACAAAGCATCAGCGGGATGGGGTCCGGGTTTGCGGGACGATCTTCATCCGCCGAAGACGCCAGTACGATCT
ACGGCAACCCGGCAGGCATGGCGCGGCTTAAACGAGAGCAGGTGAGCGTGGGGGCGGCGACGCTGTTCGCCAAATCGGAC
ATCAGCCAGACACGCAGTACGTTTGGGGGGAAGGAAGACGGCGACATGGTGCCCGCCACCACAGTACCGATGGGGTATTA
CGTGAAACCGATCGATGAGCATTGGGCATTCGGCGTCGGGTTTTATGTGCCTTTCGGGCTGATCACCGACTACGGCAGTG
GTTTTGCCGGCCGCTATTACGCCAACAAGAGTGAAGTCACCACGCTGACCTTTCAGCCGACCATCAGCTACGCCTTTAAC
GAAAAGGTGTCGATCGGATTCGGGCCGACCATCAATCGTATCGGCGGAGAGATATCGGGCATGGTGCCCAATCCACTCAG
CCCCGGGCGCAACGACGGCAAACTCAAAAGCACCGGCGATGACACCGCACTGGGCTTCAATGCTGGCGTGCTGGTGCAGG
CGACCGATCAGACCCGCCTGGGCCTGACGTATCACTCCAAAGTCAGTTACCACCTGGACGCCAAAACCAAGGTCACCGAT
GGCATCTTCAGCGTGCTGGGCGTCAGCGGCCGTAGCTATGACGCATCGCTGGATGTGGACACGCCGGAGTCGGTGGACTT
TTCGCTGACGCATCAATTCAACGACGACTGGACGCTCTATGTGGGCAGCACCTGGACACGCTGGAGCCGCTTCAAGGAAC
TGACCATTGAGAACAGCGGCTTGCCGCCGTTGCTGAGCGGGCAATTGGGGACGATCAGCGAAGAACAGAACTGGCATGAC
ACCTGGGCTCACGCGATCGGTGCGGCCTATCGATTGAATAACCAATGGGTGCTGCGTGGCGGGTTTTCGGTCGATCAGTC
ACCCGCCAACAACACCAATCGGGGGCCGCGCATTCCGACGGGCGACCGTAAGGTTGTCAGCTTCGGCGCCGGCTGGACAC
CCGTGGACAATGTCACGATCGATCTCGCGTATTCCTATCTTTGGGAGGAAAGCGTCGAGGTCAACGACACCTCGGCATCG
AGGGGGGCCTACCGTGCCAGGTACAAGAACAGTGCCAGCGGGTTCGGTACGTCGGTCAGTTATCGCTTCTAG

Upstream 100 bases:

>100_bases
TTTTGCTTCATGTGACCATTGACTGAAATGGTCACTTGGATAATATGGCTTCGCTGTCGTTCTCGATGTTGTTTTTCAGT
GATCCCATAGAGTCCAGATA

Downstream 100 bases:

>100_bases
TTGAGCGCCATCAAGCCAAATGCGGGTCGGGAGTACACGTGTCTCCCGACTCTTGAAGCGATCTGAGGTTGCTGCTCAGC
GCGCCGCTACAGAACCCGGC

Product: aromatic hydrocarbon degradation protein

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKKIMLKNPVGLAVALVSSNVLAGGFALNEQSISGMGSGFAGRSSSAEDASTIYGNPAGMARLKREQVSVGAATLFAKSD
ISQTRSTFGGKEDGDMVPATTVPMGYYVKPIDEHWAFGVGFYVPFGLITDYGSGFAGRYYANKSEVTTLTFQPTISYAFN
EKVSIGFGPTINRIGGEISGMVPNPLSPGRNDGKLKSTGDDTALGFNAGVLVQATDQTRLGLTYHSKVSYHLDAKTKVTD
GIFSVLGVSGRSYDASLDVDTPESVDFSLTHQFNDDWTLYVGSTWTRWSRFKELTIENSGLPPLLSGQLGTISEEQNWHD
TWAHAIGAAYRLNNQWVLRGGFSVDQSPANNTNRGPRIPTGDRKVVSFGAGWTPVDNVTIDLAYSYLWEESVEVNDTSAS
RGAYRARYKNSASGFGTSVSYRF

Sequences:

>Translated_423_residues
MKKIMLKNPVGLAVALVSSNVLAGGFALNEQSISGMGSGFAGRSSSAEDASTIYGNPAGMARLKREQVSVGAATLFAKSD
ISQTRSTFGGKEDGDMVPATTVPMGYYVKPIDEHWAFGVGFYVPFGLITDYGSGFAGRYYANKSEVTTLTFQPTISYAFN
EKVSIGFGPTINRIGGEISGMVPNPLSPGRNDGKLKSTGDDTALGFNAGVLVQATDQTRLGLTYHSKVSYHLDAKTKVTD
GIFSVLGVSGRSYDASLDVDTPESVDFSLTHQFNDDWTLYVGSTWTRWSRFKELTIENSGLPPLLSGQLGTISEEQNWHD
TWAHAIGAAYRLNNQWVLRGGFSVDQSPANNTNRGPRIPTGDRKVVSFGAGWTPVDNVTIDLAYSYLWEESVEVNDTSAS
RGAYRARYKNSASGFGTSVSYRF
>Mature_423_residues
MKKIMLKNPVGLAVALVSSNVLAGGFALNEQSISGMGSGFAGRSSSAEDASTIYGNPAGMARLKREQVSVGAATLFAKSD
ISQTRSTFGGKEDGDMVPATTVPMGYYVKPIDEHWAFGVGFYVPFGLITDYGSGFAGRYYANKSEVTTLTFQPTISYAFN
EKVSIGFGPTINRIGGEISGMVPNPLSPGRNDGKLKSTGDDTALGFNAGVLVQATDQTRLGLTYHSKVSYHLDAKTKVTD
GIFSVLGVSGRSYDASLDVDTPESVDFSLTHQFNDDWTLYVGSTWTRWSRFKELTIENSGLPPLLSGQLGTISEEQNWHD
TWAHAIGAAYRLNNQWVLRGGFSVDQSPANNTNRGPRIPTGDRKVVSFGAGWTPVDNVTIDLAYSYLWEESVEVNDTSAS
RGAYRARYKNSASGFGTSVSYRF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=456, Percent_Identity=25, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 45630; Mature: 45630

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMLKNPVGLAVALVSSNVLAGGFALNEQSISGMGSGFAGRSSSAEDASTIYGNPAGM
CCCEEECCCCCEEEEEECCCEEECEEEECCHHHCCCCCCCCCCCCCCCCCCEECCCCHHH
ARLKREQVSVGAATLFAKSDISQTRSTFGGKEDGDMVPATTVPMGYYVKPIDEHWAFGVG
HHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCCEEEEH
FYVPFGLITDYGSGFAGRYYANKSEVTTLTFQPTISYAFNEKVSIGFGPTINRIGGEISG
HHHHHHHHHHCCCCCCCEEECCCCCEEEEEEECEEEEEECCEEEECCCCCHHHCCCEEEC
MVPNPLSPGRNDGKLKSTGDDTALGFNAGVLVQATDQTRLGLTYHSKVSYHLDAKTKVTD
CCCCCCCCCCCCCEECCCCCCCEEECCCCEEEEECCCCEEEEEEECEEEEEECCCCHHHH
GIFSVLGVSGRSYDASLDVDTPESVDFSLTHQFNDDWTLYVGSTWTRWSRFKELTIENSG
HHHHHHCCCCCCCCCEECCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHEEEEEECCC
LPPLLSGQLGTISEEQNWHDTWAHAIGAAYRLNNQWVLRGGFSVDQSPANNTNRGPRIPT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCEEEEEECCCCCCCCCCCCCCCCCCCC
GDRKVVSFGAGWTPVDNVTIDLAYSYLWEESVEVNDTSASRGAYRARYKNSASGFGTSVS
CCCEEEEECCCCCCCCCEEEEEEEEEHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEE
YRF
ECC
>Mature Secondary Structure
MKKIMLKNPVGLAVALVSSNVLAGGFALNEQSISGMGSGFAGRSSSAEDASTIYGNPAGM
CCCEEECCCCCEEEEEECCCEEECEEEECCHHHCCCCCCCCCCCCCCCCCCEECCCCHHH
ARLKREQVSVGAATLFAKSDISQTRSTFGGKEDGDMVPATTVPMGYYVKPIDEHWAFGVG
HHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEECCCCCEEEEH
FYVPFGLITDYGSGFAGRYYANKSEVTTLTFQPTISYAFNEKVSIGFGPTINRIGGEISG
HHHHHHHHHHCCCCCCCEEECCCCCEEEEEEECEEEEEECCEEEECCCCCHHHCCCEEEC
MVPNPLSPGRNDGKLKSTGDDTALGFNAGVLVQATDQTRLGLTYHSKVSYHLDAKTKVTD
CCCCCCCCCCCCCEECCCCCCCEEECCCCEEEEECCCCEEEEEEECEEEEEECCCCHHHH
GIFSVLGVSGRSYDASLDVDTPESVDFSLTHQFNDDWTLYVGSTWTRWSRFKELTIENSG
HHHHHHCCCCCCCCCEECCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHEEEEEECCC
LPPLLSGQLGTISEEQNWHDTWAHAIGAAYRLNNQWVLRGGFSVDQSPANNTNRGPRIPT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCEEEEEECCCCCCCCCCCCCCCCCCCC
GDRKVVSFGAGWTPVDNVTIDLAYSYLWEESVEVNDTSASRGAYRARYKNSASGFGTSVS
CCCEEEEECCCCCCCCCEEEEEEEEEHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEE
YRF
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]