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The map label for this gene is nahR [H]

Identifier: 77458685

GI number: 77458685

Start: 2813677

End: 2814651

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_2460

Alternate gene names: 77458685

Gene position: 2813677-2814651 (Clockwise)

Preceding gene: 77458679

Following gene: 77458688

Centisome position: 43.7

GC content: 62.26

Gene sequence:

>975_bases
ATGAACAGAAATGAACTCCGTCGTGTCGACATCAATCTGCTGGTGGTCTTCGAGACGCTGATGCATGAGCGCAACGTCAG
CCGGGTCGGCGAGAAACTGTTTCTCGGTCAACCGACCATCAGTGCAGCGCTGGGGCGTTTGCGTGTGCTTTTCGACGATC
CGTTGTTCGTTCGTGCGGGGAGGGTGATGGAACCGACAAGGCGGGCCGAGGAAATTTTCGCCAACCTGACGCCGGCGCTG
GATGGCGTTGTCGCGGCGTTGAGCCGTTGCCAGCCCTTCGCCCCAGCTACCAGCGAGGTGACCTTTCAGGTCGGCCTGTC
CGACGATGTCGAATACGCGTTGCTCCCGCGACTGCTGCGCCAGCTTCGTAGCGAGGCGCCGAATATTGCCTTGGTGGTGC
TGCGCGTCGATCAGCAGCAGATGTCGCAGCGGCTGTTCAATGGCGAGATTTCTCTGGGCATCAGCCCTACGCTCGATCTG
CCGGCCAACGCTCGACGCAAGAGTCTACGGTCGATCCGGCCAATGCTCCTGCGCTCGGATACCCGCCCGGGCCTGCTGGC
GCTCGATGAGTTCTGCGAGCGCCCGCATGCCATCGTGTCGTCCATGGGCAAGGCCAGGGATGACACCGACCACGCGCTGG
ACCTGCTTGGACGTCGGCGCAAAGTGGTGCTGGCAGTGCCGCAGTTCAGTGCCTTGCCAAGGTTGTTGGCGCAGAGCGAC
ATGCTGGTCATCGTTCCGGATTACGTGGCCAGGGCCATGGCCTCGGTGAATGGCATCAGGGCCGAGCCGGCCCCTCTGTT
GCTGCCATCGCGGGAGCTTTCCATGGTCTGGCGTGCCGCTGCGCACAACGATTGCGCTCAGCGTTGGCTGCGTTCGCGTT
GCCAGGCATTTCTTGGCACGCCGATTGAGTTGCAGGTAGTGCCAAAATTACGCCCCGCGTTGCCCGTCGATCAGACGTTG
ATGATGGCCCGGTAG

Upstream 100 bases:

>100_bases
TCTCGCTGTCCCCAAGTACCACAGACGTCCGGCAGGCGCGCCCTTAACCTTTAACAGCTCTCCGTCGATCTCAATGGCCG
CGTGCCGGGTGGTGAACTTC

Downstream 100 bases:

>100_bases
ATAACTGCAACGGCTGTGTGATTCGCCCAATAAAAAGCTCCGACTCGATCGGAGCTTTGTTTTTAAGGGGGTGTATGTGG
CTTGCCGTCAGGAGGGCACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNRNELRRVDINLLVVFETLMHERNVSRVGEKLFLGQPTISAALGRLRVLFDDPLFVRAGRVMEPTRRAEEIFANLTPAL
DGVVAALSRCQPFAPATSEVTFQVGLSDDVEYALLPRLLRQLRSEAPNIALVVLRVDQQQMSQRLFNGEISLGISPTLDL
PANARRKSLRSIRPMLLRSDTRPGLLALDEFCERPHAIVSSMGKARDDTDHALDLLGRRRKVVLAVPQFSALPRLLAQSD
MLVIVPDYVARAMASVNGIRAEPAPLLLPSRELSMVWRAAAHNDCAQRWLRSRCQAFLGTPIELQVVPKLRPALPVDQTL
MMAR

Sequences:

>Translated_324_residues
MNRNELRRVDINLLVVFETLMHERNVSRVGEKLFLGQPTISAALGRLRVLFDDPLFVRAGRVMEPTRRAEEIFANLTPAL
DGVVAALSRCQPFAPATSEVTFQVGLSDDVEYALLPRLLRQLRSEAPNIALVVLRVDQQQMSQRLFNGEISLGISPTLDL
PANARRKSLRSIRPMLLRSDTRPGLLALDEFCERPHAIVSSMGKARDDTDHALDLLGRRRKVVLAVPQFSALPRLLAQSD
MLVIVPDYVARAMASVNGIRAEPAPLLLPSRELSMVWRAAAHNDCAQRWLRSRCQAFLGTPIELQVVPKLRPALPVDQTL
MMAR
>Mature_324_residues
MNRNELRRVDINLLVVFETLMHERNVSRVGEKLFLGQPTISAALGRLRVLFDDPLFVRAGRVMEPTRRAEEIFANLTPAL
DGVVAALSRCQPFAPATSEVTFQVGLSDDVEYALLPRLLRQLRSEAPNIALVVLRVDQQQMSQRLFNGEISLGISPTLDL
PANARRKSLRSIRPMLLRSDTRPGLLALDEFCERPHAIVSSMGKARDDTDHALDLLGRRRKVVLAVPQFSALPRLLAQSD
MLVIVPDYVARAMASVNGIRAEPAPLLLPSRELSMVWRAAAHNDCAQRWLRSRCQAFLGTPIELQVVPKLRPALPVDQTL
MMAR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=302, Percent_Identity=27.4834437086093, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786820, Length=289, Percent_Identity=22.1453287197232, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081766, Length=126, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36200; Mature: 36200

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNELRRVDINLLVVFETLMHERNVSRVGEKLFLGQPTISAALGRLRVLFDDPLFVRAG
CCCCCCEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHEECCCHHEECC
RVMEPTRRAEEIFANLTPALDGVVAALSRCQPFAPATSEVTFQVGLSDDVEYALLPRLLR
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
QLRSEAPNIALVVLRVDQQQMSQRLFNGEISLGISPTLDLPANARRKSLRSIRPMLLRSD
HHHHCCCCEEEEEEECCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
TRPGLLALDEFCERPHAIVSSMGKARDDTDHALDLLGRRRKVVLAVPQFSALPRLLAQSD
CCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCC
MLVIVPDYVARAMASVNGIRAEPAPLLLPSRELSMVWRAAAHNDCAQRWLRSRCQAFLGT
CEEEECHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
PIELQVVPKLRPALPVDQTLMMAR
CEEEEECCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MNRNELRRVDINLLVVFETLMHERNVSRVGEKLFLGQPTISAALGRLRVLFDDPLFVRAG
CCCCCCEEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHEECCCHHEECC
RVMEPTRRAEEIFANLTPALDGVVAALSRCQPFAPATSEVTFQVGLSDDVEYALLPRLLR
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
QLRSEAPNIALVVLRVDQQQMSQRLFNGEISLGISPTLDLPANARRKSLRSIRPMLLRSD
HHHHCCCCEEEEEEECCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
TRPGLLALDEFCERPHAIVSSMGKARDDTDHALDLLGRRRKVVLAVPQFSALPRLLAQSD
CCCCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCC
MLVIVPDYVARAMASVNGIRAEPAPLLLPSRELSMVWRAAAHNDCAQRWLRSRCQAFLGT
CEEEECHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
PIELQVVPKLRPALPVDQTLMMAR
CEEEEECCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]