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The map label for this gene is kipA [H]

Identifier: 77457634

GI number: 77457634

Start: 1578092

End: 1579006

Strand: Direct

Name: kipA [H]

Synonym: Pfl01_1407

Alternate gene names: 77457634

Gene position: 1578092-1579006 (Clockwise)

Preceding gene: 77457633

Following gene: 77457637

Centisome position: 24.51

GC content: 64.15

Gene sequence:

>915_bases
ATGAGCCGACTGACGATTGAAGCGAGTACGCCGCTGTGCCTGTTGCAGGATGCCGGCCGGTTTGGCGTACGGCATCTGGG
CGTGACCCAGGGTGGCGCGGCGGACTGGCGGTCGATGGCCTGGGCCAACTGGCTGCTGGGCAATGGCCTGGACTTGCCGG
TGATCGAAATTACCCTCGGCGGGTTCACGGTGGTGGCTGAAGAAGATTGCTTGCTGGCATTGGCGGGTGCCGATCTTGGC
GCGCAGATCGACGGTGAGGCGTTAGCGCCGTGGCGCAGTTTCAAACTGCGTAAAGGGCAGACCTTGACGTTCACCCAGCC
GTTGCTGGGGGCTCGGGCCTATCTGGCTGCGCCTGGCGGTTTCAGCGCGCCGCCAGTGTTGGGCAGCAGTGCCACGGTAG
TGCGCGAAGAACTCGGCGGGCTCGATGGTTTTGGCCTGCCGCTGGCCAAGGGCGCTTCGCTGAGTTATCAGGGCGAAACC
TTACTGGTGCGCGAGGTGCCGGCGGAGCATCGACCGGATCTGCGCCTCGACGCGCCGCTCGATCTGGTGCTCGGCGCGCA
GATCGGTCAGTTCAGCGGGCAGAGTCTGTTCGATGCCTTCAACCGTGCCTGGACGCTGGACAGTCGCGCCGATCGCATGG
GTATTCGTCTGTTGGGCACGGCGTTGCAGTATCAGGGCAAACCGATGATTTCCGAGGGCATTCCGCTGGGCGCGGTGCAG
GTGCCGCCGGACGGGCAGCCGATCGTGTTGCTCAATGATCGGCAGACCATTGGCGGCTATCCGCGATTGGGAGCGTTGAC
ACCGTTGGCGTTGGCCCGCCTGGCACAGTATCTGCCGGGGGCGAAGGTCAGGTTGCGCCCGGTGGTGCAGGAAGTGGCAC
ACCGGGAACACATCGAATATCTGAAGCGCTTTTGA

Upstream 100 bases:

>100_bases
ACAGCCTCATGCAACCCGGCGATACCGTACGTTTCGAAGCGGTAAGCCATGCCGAATTCATCCGCCTCGGCGGTGACGAC
ACGCCTCTGGAGGCCCTCGC

Downstream 100 bases:

>100_bases
TTGTTCTCCCGCCGCTGGCGGGGGAGCCGTTGCGGACTACTTGGACAGAAACCGCATCCCTTCTTCCAGCCCGCGCAACG
TCAACGGATACATCTGATCC

Product: allophanate hydrolase subunit 2

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSRLTIEASTPLCLLQDAGRFGVRHLGVTQGGAADWRSMAWANWLLGNGLDLPVIEITLGGFTVVAEEDCLLALAGADLG
AQIDGEALAPWRSFKLRKGQTLTFTQPLLGARAYLAAPGGFSAPPVLGSSATVVREELGGLDGFGLPLAKGASLSYQGET
LLVREVPAEHRPDLRLDAPLDLVLGAQIGQFSGQSLFDAFNRAWTLDSRADRMGIRLLGTALQYQGKPMISEGIPLGAVQ
VPPDGQPIVLLNDRQTIGGYPRLGALTPLALARLAQYLPGAKVRLRPVVQEVAHREHIEYLKRF

Sequences:

>Translated_304_residues
MSRLTIEASTPLCLLQDAGRFGVRHLGVTQGGAADWRSMAWANWLLGNGLDLPVIEITLGGFTVVAEEDCLLALAGADLG
AQIDGEALAPWRSFKLRKGQTLTFTQPLLGARAYLAAPGGFSAPPVLGSSATVVREELGGLDGFGLPLAKGASLSYQGET
LLVREVPAEHRPDLRLDAPLDLVLGAQIGQFSGQSLFDAFNRAWTLDSRADRMGIRLLGTALQYQGKPMISEGIPLGAVQ
VPPDGQPIVLLNDRQTIGGYPRLGALTPLALARLAQYLPGAKVRLRPVVQEVAHREHIEYLKRF
>Mature_303_residues
SRLTIEASTPLCLLQDAGRFGVRHLGVTQGGAADWRSMAWANWLLGNGLDLPVIEITLGGFTVVAEEDCLLALAGADLGA
QIDGEALAPWRSFKLRKGQTLTFTQPLLGARAYLAAPGGFSAPPVLGSSATVVREELGGLDGFGLPLAKGASLSYQGETL
LVREVPAEHRPDLRLDAPLDLVLGAQIGQFSGQSLFDAFNRAWTLDSRADRMGIRLLGTALQYQGKPMISEGIPLGAVQV
PPDGQPIVLLNDRQTIGGYPRLGALTPLALARLAQYLPGAKVRLRPVVQEVAHREHIEYLKRF

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=270, Percent_Identity=38.1481481481481, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319685, Length=296, Percent_Identity=25.6756756756757, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 32531; Mature: 32400

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLTIEASTPLCLLQDAGRFGVRHLGVTQGGAADWRSMAWANWLLGNGLDLPVIEITLG
CCEEEEECCCCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC
GFTVVAEEDCLLALAGADLGAQIDGEALAPWRSFKLRKGQTLTFTQPLLGARAYLAAPGG
CEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHCEECCCCEEEECCHHHCCCEEEECCCC
FSAPPVLGSSATVVREELGGLDGFGLPLAKGASLSYQGETLLVREVPAEHRPDLRLDAPL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCEECCCH
DLVLGAQIGQFSGQSLFDAFNRAWTLDSRADRMGIRLLGTALQYQGKPMISEGIPLGAVQ
HEEECCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEE
VPPDGQPIVLLNDRQTIGGYPRLGALTPLALARLAQYLPGAKVRLRPVVQEVAHREHIEY
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
LKRF
HHCC
>Mature Secondary Structure 
SRLTIEASTPLCLLQDAGRFGVRHLGVTQGGAADWRSMAWANWLLGNGLDLPVIEITLG
CEEEEECCCCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC
GFTVVAEEDCLLALAGADLGAQIDGEALAPWRSFKLRKGQTLTFTQPLLGARAYLAAPGG
CEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHCEECCCCEEEECCHHHCCCEEEECCCC
FSAPPVLGSSATVVREELGGLDGFGLPLAKGASLSYQGETLLVREVPAEHRPDLRLDAPL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCEECCCH
DLVLGAQIGQFSGQSLFDAFNRAWTLDSRADRMGIRLLGTALQYQGKPMISEGIPLGAVQ
HEEECCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEE
VPPDGQPIVLLNDRQTIGGYPRLGALTPLALARLAQYLPGAKVRLRPVVQEVAHREHIEY
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
LKRF
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]