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The map label for this gene is nahR [H]

Identifier: 77457610

GI number: 77457610

Start: 1556218

End: 1557144

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_1383

Alternate gene names: 77457610

Gene position: 1556218-1557144 (Clockwise)

Preceding gene: 77457609

Following gene: 77457611

Centisome position: 24.17

GC content: 63.32

Gene sequence:

>927_bases
ATGAACCGCAATGAACTACGCAAGGCCGACATCAACCTGATGGTGGTGTTCGAGACCTTGATGCTCGAACGCAACGTGAC
CCGGGCCGCCGAGAAACTGTTTCTCGGCCAGCCGACCATCAGTTCGGCGCTCAACCGTCTGCGCACCATGCTTAACGATC
CGTTGTTCATCCGCGTCGGCCATCGCATGGAGCCGACCGCCCGCGCCGAAGACATTTATCGCCACCTGAAACCCGCGCTC
GACTCGCTGTCGGTGGCGCTCAGTCTGACCCGCGATTTCGACCCCGCTGTCAGCACCATGACCTTCCGAATCGGTCTGTC
GGATGACGTCGAATTCGGCCTGCTGCCACCGCTGTTGCGCGCCTTGCGCCAGGAAGCGCCGAGCGTGGTGTTTGTGGTGC
AGCACGTCGATTACTGGCGGATTCCCGACCTGTTGGCCGCCGGCGACATCACCGTCGGCATCAGCCAGACCCGTGGTCTG
CCGGCCAATGCCAAGCGCAAATTGTTGCGACACATTCAGCCGAGCATCCTGCGCGCCGACAAGTCCGACACGCCGCTGAC
CCTCGATGAATATTGCGCCCGCCCGCACGTGCTGGTTTCCCACACCGCCAATGTCAGTGGCTACGCCGATGAGTGGCTGG
CGGACATCGGTCGCACCCGTCAGGTGGTGCTGTCGGTGCCGCAGTACAGTTCGTTGCCGGCGCTGCTGGCCGGCACCGAT
CTGATTGCCAGCCTGCCGGACTACACCGCCGACGCCATGGCCGCTTCCGGACTGCTGTTCAAGGAGCCGTTCCCGTTCAA
GACTCCGACCCTCGATCTGTCGATGGTCTGGCTCAGCCACGTTGACAGCGACCCGGGCGAGCGCTGGCTGCGTTCGCGGC
TGGAGCAATTCATGAGTGAGCGGCCGGTGATGTCGTCGCTGGAGTGA

Upstream 100 bases:

>100_bases
GGGCTGAAGACGTTGACGGTGCAATGACGCAGCGTTTCGATGGACGCCGGCCCCGCGGCCTTTCTACACTGCCCGCAATC
TGGGGATCGGGGGGCAATGG

Downstream 100 bases:

>100_bases
GTCAGGCATTGCTGTGTTATATGTACGACCTTTCCGCCGAACCACTGGAGCACCGAGATGCCGCACCTGCACCTGGAATA
CACCGCCAACCTGCCGCAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNRNELRKADINLMVVFETLMLERNVTRAAEKLFLGQPTISSALNRLRTMLNDPLFIRVGHRMEPTARAEDIYRHLKPAL
DSLSVALSLTRDFDPAVSTMTFRIGLSDDVEFGLLPPLLRALRQEAPSVVFVVQHVDYWRIPDLLAAGDITVGISQTRGL
PANAKRKLLRHIQPSILRADKSDTPLTLDEYCARPHVLVSHTANVSGYADEWLADIGRTRQVVLSVPQYSSLPALLAGTD
LIASLPDYTADAMAASGLLFKEPFPFKTPTLDLSMVWLSHVDSDPGERWLRSRLEQFMSERPVMSSLE

Sequences:

>Translated_308_residues
MNRNELRKADINLMVVFETLMLERNVTRAAEKLFLGQPTISSALNRLRTMLNDPLFIRVGHRMEPTARAEDIYRHLKPAL
DSLSVALSLTRDFDPAVSTMTFRIGLSDDVEFGLLPPLLRALRQEAPSVVFVVQHVDYWRIPDLLAAGDITVGISQTRGL
PANAKRKLLRHIQPSILRADKSDTPLTLDEYCARPHVLVSHTANVSGYADEWLADIGRTRQVVLSVPQYSSLPALLAGTD
LIASLPDYTADAMAASGLLFKEPFPFKTPTLDLSMVWLSHVDSDPGERWLRSRLEQFMSERPVMSSLE
>Mature_308_residues
MNRNELRKADINLMVVFETLMLERNVTRAAEKLFLGQPTISSALNRLRTMLNDPLFIRVGHRMEPTARAEDIYRHLKPAL
DSLSVALSLTRDFDPAVSTMTFRIGLSDDVEFGLLPPLLRALRQEAPSVVFVVQHVDYWRIPDLLAAGDITVGISQTRGL
PANAKRKLLRHIQPSILRADKSDTPLTLDEYCARPHVLVSHTANVSGYADEWLADIGRTRQVVLSVPQYSSLPALLAGTD
LIASLPDYTADAMAASGLLFKEPFPFKTPTLDLSMVWLSHVDSDPGERWLRSRLEQFMSERPVMSSLE

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=25.4180602006689, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786820, Length=128, Percent_Identity=30.46875, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081766, Length=296, Percent_Identity=25.3378378378378, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=22.5165562913907, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34500; Mature: 34500

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNELRKADINLMVVFETLMLERNVTRAAEKLFLGQPTISSALNRLRTMLNDPLFIRVG
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEC
HRMEPTARAEDIYRHLKPALDSLSVALSLTRDFDPAVSTMTFRIGLSDDVEFGLLPPLLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCCCCCCCHHHHHH
ALRQEAPSVVFVVQHVDYWRIPDLLAAGDITVGISQTRGLPANAKRKLLRHIQPSILRAD
HHHHHCCCEEEEEECCCCCCCCHHHHCCCEEEECHHCCCCCCHHHHHHHHHHCHHHHHCC
KSDTPLTLDEYCARPHVLVSHTANVSGYADEWLADIGRTRQVVLSVPQYSSLPALLAGTD
CCCCCEEHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
LIASLPDYTADAMAASGLLFKEPFPFKTPTLDLSMVWLSHVDSDPGERWLRSRLEQFMSE
HHHHCCCCHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
RPVMSSLE
CCCHHCCC
>Mature Secondary Structure
MNRNELRKADINLMVVFETLMLERNVTRAAEKLFLGQPTISSALNRLRTMLNDPLFIRVG
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEC
HRMEPTARAEDIYRHLKPALDSLSVALSLTRDFDPAVSTMTFRIGLSDDVEFGLLPPLLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCCCCCCCHHHHHH
ALRQEAPSVVFVVQHVDYWRIPDLLAAGDITVGISQTRGLPANAKRKLLRHIQPSILRAD
HHHHHCCCEEEEEECCCCCCCCHHHHCCCEEEECHHCCCCCCHHHHHHHHHHCHHHHHCC
KSDTPLTLDEYCARPHVLVSHTANVSGYADEWLADIGRTRQVVLSVPQYSSLPALLAGTD
CCCCCEEHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
LIASLPDYTADAMAASGLLFKEPFPFKTPTLDLSMVWLSHVDSDPGERWLRSRLEQFMSE
HHHHCCCCHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
RPVMSSLE
CCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]