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The map label for this gene is nahR [H]

Identifier: 77457545

GI number: 77457545

Start: 1493306

End: 1494208

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_1318

Alternate gene names: 77457545

Gene position: 1493306-1494208 (Clockwise)

Preceding gene: 77457543

Following gene: 77457546

Centisome position: 23.19

GC content: 65.56

Gene sequence:

>903_bases
ATGAATGATTTGCGCCGCATCGACCTCAATCTGCTGGTGATCCTCGACGCCTTGCTCACCGAGCAACACGTGACCCGCGC
TGCCGAGCGTCTGCACCTGAGTCAACCGGCGGTCAGCCATGCGTTGGCGCGTCTGCGTGACTTGCTCGACGATCCGCTGC
TGGTGCGGGCCGGTTCGGGGTTGGTCCCCACCGCGCGGGCGTTGGAGCTGGCGGCGCCGCTGACGGAAACCCTGGCCCAG
GTGCAATCGCTGCTGGCGCCGAACACCTTTGATCCGACCAGCGCCCGTCGGACCTTTCGCCTCGCGATGTCGGACTACGG
CGCGGCGCTCATCCTGCCCGGGCTGATTCGCACCTTGCGCGCAGAAGCACCGGGCATCGACCTGCAAATCAGCCACGCCA
GCCGCGAAGGCATGGTCGAAGGCCTGCTCAACGGCGACATCGACCTCGCCGCTGGCGTACTCCCCGAACTGCCCGGCGAA
CTGCGCAGCACGCCGTTGTTCGAAGAGCGCTACGTCTGCCTCCTGGATCGTCAGAGCCTTCCCGCCGGAGGTGTTCTCGA
CTTGCCAACCTATCTCTCCCGTCCCCATGTCTTGCTGGAAATGCGCGGCAGCGGCACCCCGGAAATCGAACGCACCCTGA
CCGCGCTGCGTGAACGCCGCCGCGTCGCCATCAGCCTGCCGCACTGGAGCGTTGCGCCGCGGTTCATCAGCGGCACGGAT
CTGATCCTGACCGTGGCTTCGCGGGCGTTGAACGAGGTGGATGACCAATCGCTGATCGTCTTGCCGCCGCCGTTTGAAAT
TGCACCGTTCACGTTTGTCTCGGCGTGGCACAAGCGGCGGGGCGGGGATCAGGCGTTGAACTGGTTGAATCGGCGGATTG
AGCAGGGGATAGTGCGCGGCTGA

Upstream 100 bases:

>100_bases
CATCGTTCCCATGATCGTTCTCCGGCAAAGGTTTTGCTGGACTCTAGGGTATTCGTCGAGCAGATTTAAATTCTGTTTTG
GTATCCGGAACATGCATCGA

Downstream 100 bases:

>100_bases
CAAACATCAAGGAGCGGGGCGTGACAGTGAAGTCTGGGGTCGTTGGTTGGGTGGCGCTGTGTGGGGCGTTGATGGCGGGG
CAGGTGTTGGCTGATTGTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNDLRRIDLNLLVILDALLTEQHVTRAAERLHLSQPAVSHALARLRDLLDDPLLVRAGSGLVPTARALELAAPLTETLAQ
VQSLLAPNTFDPTSARRTFRLAMSDYGAALILPGLIRTLRAEAPGIDLQISHASREGMVEGLLNGDIDLAAGVLPELPGE
LRSTPLFEERYVCLLDRQSLPAGGVLDLPTYLSRPHVLLEMRGSGTPEIERTLTALRERRRVAISLPHWSVAPRFISGTD
LILTVASRALNEVDDQSLIVLPPPFEIAPFTFVSAWHKRRGGDQALNWLNRRIEQGIVRG

Sequences:

>Translated_300_residues
MNDLRRIDLNLLVILDALLTEQHVTRAAERLHLSQPAVSHALARLRDLLDDPLLVRAGSGLVPTARALELAAPLTETLAQ
VQSLLAPNTFDPTSARRTFRLAMSDYGAALILPGLIRTLRAEAPGIDLQISHASREGMVEGLLNGDIDLAAGVLPELPGE
LRSTPLFEERYVCLLDRQSLPAGGVLDLPTYLSRPHVLLEMRGSGTPEIERTLTALRERRRVAISLPHWSVAPRFISGTD
LILTVASRALNEVDDQSLIVLPPPFEIAPFTFVSAWHKRRGGDQALNWLNRRIEQGIVRG
>Mature_300_residues
MNDLRRIDLNLLVILDALLTEQHVTRAAERLHLSQPAVSHALARLRDLLDDPLLVRAGSGLVPTARALELAAPLTETLAQ
VQSLLAPNTFDPTSARRTFRLAMSDYGAALILPGLIRTLRAEAPGIDLQISHASREGMVEGLLNGDIDLAAGVLPELPGE
LRSTPLFEERYVCLLDRQSLPAGGVLDLPTYLSRPHVLLEMRGSGTPEIERTLTALRERRRVAISLPHWSVAPRFISGTD
LILTVASRALNEVDDQSLIVLPPPFEIAPFTFVSAWHKRRGGDQALNWLNRRIEQGIVRG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=28.3276450511945, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=26.8456375838926, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786820, Length=169, Percent_Identity=31.3609467455621, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081766, Length=124, Percent_Identity=33.0645161290323, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32980; Mature: 32980

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLRRIDLNLLVILDALLTEQHVTRAAERLHLSQPAVSHALARLRDLLDDPLLVRAGSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCC
LVPTARALELAAPLTETLAQVQSLLAPNTFDPTSARRTFRLAMSDYGAALILPGLIRTLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEAPGIDLQISHASREGMVEGLLNGDIDLAAGVLPELPGELRSTPLFEERYVCLLDRQSL
HCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCHHHCEEEEEECCCC
PAGGVLDLPTYLSRPHVLLEMRGSGTPEIERTLTALRERRRVAISLPHWSVAPRFISGTD
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCH
LILTVASRALNEVDDQSLIVLPPPFEIAPFTFVSAWHKRRGGDQALNWLNRRIEQGIVRG
HHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDLRRIDLNLLVILDALLTEQHVTRAAERLHLSQPAVSHALARLRDLLDDPLLVRAGSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCC
LVPTARALELAAPLTETLAQVQSLLAPNTFDPTSARRTFRLAMSDYGAALILPGLIRTLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
AEAPGIDLQISHASREGMVEGLLNGDIDLAAGVLPELPGELRSTPLFEERYVCLLDRQSL
HCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCHHHCEEEEEECCCC
PAGGVLDLPTYLSRPHVLLEMRGSGTPEIERTLTALRERRRVAISLPHWSVAPRFISGTD
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCH
LILTVASRALNEVDDQSLIVLPPPFEIAPFTFVSAWHKRRGGDQALNWLNRRIEQGIVRG
HHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]