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The map label for this gene is ttuB [H]

Identifier: 77457543

GI number: 77457543

Start: 1491363

End: 1492694

Strand: Direct

Name: ttuB [H]

Synonym: Pfl01_1316

Alternate gene names: 77457543

Gene position: 1491363-1492694 (Clockwise)

Preceding gene: 77457542

Following gene: 77457545

Centisome position: 23.16

GC content: 61.41

Gene sequence:

>1332_bases
ATGAGCCTCAATGTAATGGAGGCGGGCGCAAGCTCGTCCGTCGATCACGATGCCGAAAAAGCCCTGGTCAGCAAGGTCGC
CTGGCGCCTGATGCCGTTGATCATGGTCTGCTACCTGTTCGCGTTCTTCGACCGCATCAACATCAGTTTCGCCAAGTTCC
AGTTGCAGGCCGACCTGAGCCTGAGCGACACCGCTTACGGTCTCGGTGCCGGGCTGTTCGTGGTCGGTTACGTGCTGTTC
GAAGTACCGAGCAACATGATGCTGTACAAGGTTGGCGCGCGGCGCTGGATCGCCCGGATCATGATGTCCTGGGGCGTGGC
GACGGCGCTGATGGTGTTCGTCAACAGTGAATGGCAGTTCTACGTGCTGCGCTTTCTGATCGGCGCGATGGAGGCCGGTT
TCGCCCCCGGCGTGCTGTATTACCTGACGCTGTGGTTCCCGCAGCACTTCCGTGGCCGCATCACCTCAATGCTGTTTCTG
GCCTCGGCGTTTGCCGGGCTGGTCGGTGCGCCGTTCTCCGGACTGGTGCTGGAACACCTTGATGGCGTGTTGCAGATGCG
CGGCTGGCACTGGTTGTTTCTGCTCGGTGGCGTGCCCTGTGTCGGCCTCGGGTTTTTGGTACTGACCTTGCTCAAGGACC
GCATCGAGGACGCTCACTGGCTGACCCCGGAAGAGAAAAAACTGCTGGCCAGCCGCATCGCCCATCACGAACCGCACAAG
AGCGGCGGCTCGTTGCTGGCGGCGCTGAAGATTCCGGGTTTCCTGACTTTGGGGCTGATCTACTTCCTGATCCAGGTCGC
GTCCTACGGCCTGAATTTCTGGGCTCCGCAACTGATCCGCAGTGCCGGCACCGAGAGCCCGGTGATGATCGGCCTGCTGA
CCTCGATCCCTTACATTTGTGGTGCGATCAGCATGGTGGTGATCGGTCGTCTGTCCGATGCTACGGGTGAGCGGCGCAAG
TTTGTCGCGGGGCTGGTGATCGTCGGCGCCATCGGCTTTTTCAGCGCGGGGATTTTTGCCAGCCACACCACGTTTTTGAT
CGTCGCTCTTGGCTTGTTGGGCGCCGGGATCATTGCGTCGATTCCGAGCTTCTGGACCTTGCCACCGAAACTGCTGGCGG
GTGCCGGGGCCGGTGCGGCGGGCGGGATTGCGGTGATCAATACACTGGGGCAGTTCGGCGGCATCGTCAGTCCGGTGATG
GTCGGCCGGATCAAGGACCTGACTGGCAGTACTACACCGGCACTGTATGTCATCGGTGTGGCGGCACTGATCGCGGCGGC
GTTGCTGCTGTGGGGGCTGCCGCAGAAATTGCGCACACTCGACAAGTACTGA

Upstream 100 bases:

>100_bases
CACCCGATGCCCACCTGATGTCACACGCTCACTGACTTACCCCCAACCAGACAACAAAAACAATCGGACGCCCACCGGCA
GTCCGCCTGGAGAAAAAACT

Downstream 100 bases:

>100_bases
GGTTGCGGGCTGGTCGTTCCGATCACGCGAACGATCAGCCCGCCGGTGCCAGGGACCTGGCGGCCGAGTCACCAAACTGG
ATCAGCACCACTCCCGCCAT

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSLNVMEAGASSSVDHDAEKALVSKVAWRLMPLIMVCYLFAFFDRINISFAKFQLQADLSLSDTAYGLGAGLFVVGYVLF
EVPSNMMLYKVGARRWIARIMMSWGVATALMVFVNSEWQFYVLRFLIGAMEAGFAPGVLYYLTLWFPQHFRGRITSMLFL
ASAFAGLVGAPFSGLVLEHLDGVLQMRGWHWLFLLGGVPCVGLGFLVLTLLKDRIEDAHWLTPEEKKLLASRIAHHEPHK
SGGSLLAALKIPGFLTLGLIYFLIQVASYGLNFWAPQLIRSAGTESPVMIGLLTSIPYICGAISMVVIGRLSDATGERRK
FVAGLVIVGAIGFFSAGIFASHTTFLIVALGLLGAGIIASIPSFWTLPPKLLAGAGAGAAGGIAVINTLGQFGGIVSPVM
VGRIKDLTGSTTPALYVIGVAALIAAALLLWGLPQKLRTLDKY

Sequences:

>Translated_443_residues
MSLNVMEAGASSSVDHDAEKALVSKVAWRLMPLIMVCYLFAFFDRINISFAKFQLQADLSLSDTAYGLGAGLFVVGYVLF
EVPSNMMLYKVGARRWIARIMMSWGVATALMVFVNSEWQFYVLRFLIGAMEAGFAPGVLYYLTLWFPQHFRGRITSMLFL
ASAFAGLVGAPFSGLVLEHLDGVLQMRGWHWLFLLGGVPCVGLGFLVLTLLKDRIEDAHWLTPEEKKLLASRIAHHEPHK
SGGSLLAALKIPGFLTLGLIYFLIQVASYGLNFWAPQLIRSAGTESPVMIGLLTSIPYICGAISMVVIGRLSDATGERRK
FVAGLVIVGAIGFFSAGIFASHTTFLIVALGLLGAGIIASIPSFWTLPPKLLAGAGAGAAGGIAVINTLGQFGGIVSPVM
VGRIKDLTGSTTPALYVIGVAALIAAALLLWGLPQKLRTLDKY
>Mature_442_residues
SLNVMEAGASSSVDHDAEKALVSKVAWRLMPLIMVCYLFAFFDRINISFAKFQLQADLSLSDTAYGLGAGLFVVGYVLFE
VPSNMMLYKVGARRWIARIMMSWGVATALMVFVNSEWQFYVLRFLIGAMEAGFAPGVLYYLTLWFPQHFRGRITSMLFLA
SAFAGLVGAPFSGLVLEHLDGVLQMRGWHWLFLLGGVPCVGLGFLVLTLLKDRIEDAHWLTPEEKKLLASRIAHHEPHKS
GGSLLAALKIPGFLTLGLIYFLIQVASYGLNFWAPQLIRSAGTESPVMIGLLTSIPYICGAISMVVIGRLSDATGERRKF
VAGLVIVGAIGFFSAGIFASHTTFLIVALGLLGAGIIASIPSFWTLPPKLLAGAGAGAAGGIAVINTLGQFGGIVSPVMV
GRIKDLTGSTTPALYVIGVAALIAAALLLWGLPQKLRTLDKY

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=411, Percent_Identity=36.4963503649635, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1789152, Length=452, Percent_Identity=25.6637168141593, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1789515, Length=447, Percent_Identity=24.1610738255034, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=25.4672897196262, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=22.6044226044226, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082404, Length=451, Percent_Identity=24.390243902439, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=332, Percent_Identity=25, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322025, Length=237, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=229, Percent_Identity=26.2008733624454, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584153, Length=367, Percent_Identity=24.5231607629428, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47649; Mature: 47518

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNVMEAGASSSVDHDAEKALVSKVAWRLMPLIMVCYLFAFFDRINISFAKFQLQADLS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCC
LSDTAYGLGAGLFVVGYVLFEVPSNMMLYKVGARRWIARIMMSWGVATALMVFVNSEWQF
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YVLRFLIGAMEAGFAPGVLYYLTLWFPQHFRGRITSMLFLASAFAGLVGAPFSGLVLEHL
HHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DGVLQMRGWHWLFLLGGVPCVGLGFLVLTLLKDRIEDAHWLTPEEKKLLASRIAHHEPHK
HHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
SGGSLLAALKIPGFLTLGLIYFLIQVASYGLNFWAPQLIRSAGTESPVMIGLLTSIPYIC
CCCCEEEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
GAISMVVIGRLSDATGERRKFVAGLVIVGAIGFFSAGIFASHTTFLIVALGLLGAGIIAS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPSFWTLPPKLLAGAGAGAAGGIAVINTLGQFGGIVSPVMVGRIKDLTGSTTPALYVIGV
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALIAAALLLWGLPQKLRTLDKY
HHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
SLNVMEAGASSSVDHDAEKALVSKVAWRLMPLIMVCYLFAFFDRINISFAKFQLQADLS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCC
LSDTAYGLGAGLFVVGYVLFEVPSNMMLYKVGARRWIARIMMSWGVATALMVFVNSEWQF
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YVLRFLIGAMEAGFAPGVLYYLTLWFPQHFRGRITSMLFLASAFAGLVGAPFSGLVLEHL
HHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DGVLQMRGWHWLFLLGGVPCVGLGFLVLTLLKDRIEDAHWLTPEEKKLLASRIAHHEPHK
HHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
SGGSLLAALKIPGFLTLGLIYFLIQVASYGLNFWAPQLIRSAGTESPVMIGLLTSIPYIC
CCCCEEEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
GAISMVVIGRLSDATGERRKFVAGLVIVGAIGFFSAGIFASHTTFLIVALGLLGAGIIAS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPSFWTLPPKLLAGAGAGAAGGIAVINTLGQFGGIVSPVMVGRIKDLTGSTTPALYVIGV
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALIAAALLLWGLPQKLRTLDKY
HHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]