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The map label for this gene is exuT [H]

Identifier: 77457481

GI number: 77457481

Start: 1426763

End: 1428112

Strand: Direct

Name: exuT [H]

Synonym: Pfl01_1254

Alternate gene names: 77457481

Gene position: 1426763-1428112 (Clockwise)

Preceding gene: 77457478

Following gene: 77457483

Centisome position: 22.16

GC content: 63.26

Gene sequence:

>1350_bases
ATGCAGAACTCGACCCAAGCGGCGAATGCCTGGCGCATTCTGTTCCTGCTGTTCCTTGCCAACCTGTTCAACTTCTTCGA
CCGCACCATCCCGGCGATCATCATCGAGCCGATCCGCATGGAATGGCACCTCAGCGACTTTCAGCTGGGGATTGTCGGCA
CTGCGTTCACTCTGGTCTACGCGATTGCCGGGCTACCACTGGGCCGAATGGCCGACACCGGTTCGCGCAGCAAACTGATG
GGTTGGGGCCTGGCGACCTGGAGCGCGCTCACTGCCGTGAACGGTCTGGTCGGCAGTTTCTGGAGTTTTCTGCTGGTGCG
CATGGGCATCGGCATCGGTGAAGCCAGTTACGCGCCCGCCGCCAACTCGCTGATCGGCGACCTGTTCCCGGCCCATCGCC
GGGCCCGGGCCATGGGCATCTTCATGCTCGGCCTGCCGCTGGGACTGCTGCTGGCCTTCTTCACCATCGGCTGGATGGTC
AAGGCATTCGACAGCTGGCGCGCACCGTTTTTCATCGCCGCCGTGCCGGGGCTGGTGCTGGCGGTGTTCATGTTTTTCAT
CAAGGAACCCAAGCGTGGCGCGGCGGAAACCGTACAGGTGTCCCAGGAGAAAGTCGACAGGCCGATTCGTCGGGTCCTCG
CCATTCCGACCTTCCTGTGGCTGGTGATGGCCGGGCTGTGCTTCAACTTCGCGACCTACGCCTGCAACTCGTTCCTGGTG
CCGATGCTCCAGCGTTATTTCCTGATGCCGTTGCAGGAAGCGGCGGTGGCGACCGGGGTAATCGTCGGTGTGACCGGGTT
GATCGGCCTGACCCTCGGCGGCTGGATCGCCGACAAGATTCACCAGCGGGTGGCCAACGGGCGACTGCTGTTTGCCGCGT
TCAGCCTGATCATCTCGACCCTGTGCACGGCGTGGGCGCTGCATGCCGGGCGTATCGAGATCGGGGTGTTTGTCGCGGTG
TTCAGTGTGGGCTGGCTGTTCGCCTACAACTTCTACACCTGCGTGTACACGGCGATTCAGGACGTGGTCGAGCCGCGCCT
GCGGGCTACGGCGATGGCGCTGTTCTTTGCCGGCTTGTATTTGCTCGGCGGCGGGCTGGGTCCGGTGGTGGTCGGCGGCT
TGTCGGATCACTTCGCCAAGTCGGCGATGGTCGCGGCGGGCGCCGAGCAGATGACCGAAGCCTTCAAGGCCGTCGGCCTG
CATGATGCGATGTACCTGATTCCGGTGGCGTTGTTCCTGACCATGGTGTTCCTGTTCCTCGCCTCGCGCTGCTTTGTGCG
GGATGCGAAGCGGATGAAGGAGGGGCTGGTGGCAGTGGTTGAGCCGCAGAATCAGGCCGTTACCGCTTGA

Upstream 100 bases:

>100_bases
CGAATGATCACAGACAGCCCCGACGAGCGTGACTAGATTGCAGGTTCCGGGCTCGGATGCGTTGGCAGTGAAGCCCTCAT
AACAATAAAGAGACGGACCC

Downstream 100 bases:

>100_bases
TCGGAGAGGCAAACAAAAAGGCCCGCATCGCTGCGGGCCTTTTCGTTTTTGGCGATGGAGCAGGGCGGTTTAACCCGCCA
CCAGCACCCGGATCGCTTCC

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQNSTQAANAWRILFLLFLANLFNFFDRTIPAIIIEPIRMEWHLSDFQLGIVGTAFTLVYAIAGLPLGRMADTGSRSKLM
GWGLATWSALTAVNGLVGSFWSFLLVRMGIGIGEASYAPAANSLIGDLFPAHRRARAMGIFMLGLPLGLLLAFFTIGWMV
KAFDSWRAPFFIAAVPGLVLAVFMFFIKEPKRGAAETVQVSQEKVDRPIRRVLAIPTFLWLVMAGLCFNFATYACNSFLV
PMLQRYFLMPLQEAAVATGVIVGVTGLIGLTLGGWIADKIHQRVANGRLLFAAFSLIISTLCTAWALHAGRIEIGVFVAV
FSVGWLFAYNFYTCVYTAIQDVVEPRLRATAMALFFAGLYLLGGGLGPVVVGGLSDHFAKSAMVAAGAEQMTEAFKAVGL
HDAMYLIPVALFLTMVFLFLASRCFVRDAKRMKEGLVAVVEPQNQAVTA

Sequences:

>Translated_449_residues
MQNSTQAANAWRILFLLFLANLFNFFDRTIPAIIIEPIRMEWHLSDFQLGIVGTAFTLVYAIAGLPLGRMADTGSRSKLM
GWGLATWSALTAVNGLVGSFWSFLLVRMGIGIGEASYAPAANSLIGDLFPAHRRARAMGIFMLGLPLGLLLAFFTIGWMV
KAFDSWRAPFFIAAVPGLVLAVFMFFIKEPKRGAAETVQVSQEKVDRPIRRVLAIPTFLWLVMAGLCFNFATYACNSFLV
PMLQRYFLMPLQEAAVATGVIVGVTGLIGLTLGGWIADKIHQRVANGRLLFAAFSLIISTLCTAWALHAGRIEIGVFVAV
FSVGWLFAYNFYTCVYTAIQDVVEPRLRATAMALFFAGLYLLGGGLGPVVVGGLSDHFAKSAMVAAGAEQMTEAFKAVGL
HDAMYLIPVALFLTMVFLFLASRCFVRDAKRMKEGLVAVVEPQNQAVTA
>Mature_449_residues
MQNSTQAANAWRILFLLFLANLFNFFDRTIPAIIIEPIRMEWHLSDFQLGIVGTAFTLVYAIAGLPLGRMADTGSRSKLM
GWGLATWSALTAVNGLVGSFWSFLLVRMGIGIGEASYAPAANSLIGDLFPAHRRARAMGIFMLGLPLGLLLAFFTIGWMV
KAFDSWRAPFFIAAVPGLVLAVFMFFIKEPKRGAAETVQVSQEKVDRPIRRVLAIPTFLWLVMAGLCFNFATYACNSFLV
PMLQRYFLMPLQEAAVATGVIVGVTGLIGLTLGGWIADKIHQRVANGRLLFAAFSLIISTLCTAWALHAGRIEIGVFVAV
FSVGWLFAYNFYTCVYTAIQDVVEPRLRATAMALFFAGLYLLGGGLGPVVVGGLSDHFAKSAMVAAGAEQMTEAFKAVGL
HDAMYLIPVALFLTMVFLFLASRCFVRDAKRMKEGLVAVVEPQNQAVTA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=446, Percent_Identity=23.542600896861, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI215490102, Length=383, Percent_Identity=26.6318537859008, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI215490096, Length=408, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI14042968, Length=408, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239645, Length=379, Percent_Identity=26.1213720316623, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI215490100, Length=394, Percent_Identity=26.1421319796954, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI215490098, Length=383, Percent_Identity=25.5874673629243, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI2367379, Length=318, Percent_Identity=27.6729559748428, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789152, Length=324, Percent_Identity=24.3827160493827, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789515, Length=202, Percent_Identity=28.2178217821782, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082320, Length=194, Percent_Identity=26.2886597938144, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193209775, Length=472, Percent_Identity=23.9406779661017, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71992409, Length=471, Percent_Identity=24.416135881104, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17539092, Length=457, Percent_Identity=24.507658643326, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17557872, Length=476, Percent_Identity=23.5294117647059, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864456, Length=394, Percent_Identity=25.6345177664975, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24654039, Length=394, Percent_Identity=25.6345177664975, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24654037, Length=395, Percent_Identity=25.3164556962025, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24654041, Length=395, Percent_Identity=25.3164556962025, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654044, Length=193, Percent_Identity=27.4611398963731, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640209, Length=195, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48943; Mature: 48943

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]