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The map label for this gene is namA [H]

Identifier: 77457263

GI number: 77457263

Start: 1200952

End: 1202058

Strand: Direct

Name: namA [H]

Synonym: Pfl01_1036

Alternate gene names: 77457263

Gene position: 1200952-1202058 (Clockwise)

Preceding gene: 77457262

Following gene: 77457264

Centisome position: 18.65

GC content: 62.87

Gene sequence:

>1107_bases
ATGAGTCTGCTGCTTGAACCCTTTACCCTTCGCCAACTGACCCTGTCCAACCGCATCGCCGTGTCGCCCATGTGCCAGTA
TTCCAGCGTCGATGGCCTGGCCAATGACTGGCATCTGGTGCACCTCGGCAGTCGTGCCGTGGGGGGCGCTGGCCTGGTGT
TTACCGAAGCTACGGCGATCACGGCCGACGGGCGGATCACCGCCGAAGACCTGGGCCTGTGGAACGACGAACAGATCCTA
CCCCTGCAACGCATCACCCGTTTCATCAACGCGCAGGGCGCAGTGGCCGGCATTCAATTGGCTCACGCCGGGCGCAAGGC
CAGCACCCATCGGCCGTGGATCGGCAAGCACGGCAGCGTCAAACCGGAGGACGGTGGCTGGATCCCGGTGGGGCCTTCGC
CGATTGCCTTCGACCCGCAACACACCCAACCGAAACAGCTGGATGAAGGGCAGATCGCCCAGGTCATTCAGGATTTCGTG
GCCGCAGCCAAACGTGCGCTGACCGCCGGTTTCAGTGTGGTCGAGGTGCATGCGGCGCACGGTTATCTGCTGCACCAGTT
TCTATCACCGCTGAGTAATCAGCGACGTGACCAGTACGGCGGTTCGTTCGAAAACCGTATTCGTCTGGTGCTGCAAGTGA
CCGAGGCGGTACGCGCGGTGTGGCCGGAAGAACTGCCGGTGTTCGTGCGCCTTTCGGCTACCGATTGGGTGGAAGACGGC
TGGAATCCCGATGAAACCGTGGAGCTGGCGCGACGCCTGAAAGCCTTGGGGGCTGATCTGATCGATGTGTCATCGGGCGG
CACGGCAGTCAACGCGGAAATCCCCGTGGGGCCGGGATATCAGACGCGCTTCGCCGAACGGGTGCGCAAGGAGTCAGGCA
TCGCCACCGGCACCGTGGGAATGATTACCGAGCCGGCTCAGGCCGAGCACATCCTGAGAACCTGCCAGGCCGATATCATC
TTCCTCGCCCGTGAGCTGCTGCGTGATCCGTACTGGCCACTGCACGCCGACGATGACCTGGGAGGACGCAAAGCGGTGTG
GCCGGCGCAGTATCAGCGTGCGACCCATCGGGATCAGCCGATTCACGAGTCTGATCTGCGGGATTGA

Upstream 100 bases:

>100_bases
ATTTTTTGCCCGCGGGGGCGGGTGCTGCACCTTTTTCCTGTCACTCGTCGACTTTTCAAACAGAACCCTGGAGCCTGCCC
ACTGATTTGAGAGGTGCCCC

Downstream 100 bases:

>100_bases
TTCCGACCGGTCGCAAAGCCTATAAAACCCGCCATTGAACCGGCGGGTTTTTTCTTGCCTGCCGTCCGGAATTGCAAAGG
AATGAAACGCGATGTTGATC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSLLLEPFTLRQLTLSNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVFTEATAITADGRITAEDLGLWNDEQIL
PLQRITRFINAQGAVAGIQLAHAGRKASTHRPWIGKHGSVKPEDGGWIPVGPSPIAFDPQHTQPKQLDEGQIAQVIQDFV
AAAKRALTAGFSVVEVHAAHGYLLHQFLSPLSNQRRDQYGGSFENRIRLVLQVTEAVRAVWPEELPVFVRLSATDWVEDG
WNPDETVELARRLKALGADLIDVSSGGTAVNAEIPVGPGYQTRFAERVRKESGIATGTVGMITEPAQAEHILRTCQADII
FLARELLRDPYWPLHADDDLGGRKAVWPAQYQRATHRDQPIHESDLRD

Sequences:

>Translated_368_residues
MSLLLEPFTLRQLTLSNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVFTEATAITADGRITAEDLGLWNDEQIL
PLQRITRFINAQGAVAGIQLAHAGRKASTHRPWIGKHGSVKPEDGGWIPVGPSPIAFDPQHTQPKQLDEGQIAQVIQDFV
AAAKRALTAGFSVVEVHAAHGYLLHQFLSPLSNQRRDQYGGSFENRIRLVLQVTEAVRAVWPEELPVFVRLSATDWVEDG
WNPDETVELARRLKALGADLIDVSSGGTAVNAEIPVGPGYQTRFAERVRKESGIATGTVGMITEPAQAEHILRTCQADII
FLARELLRDPYWPLHADDDLGGRKAVWPAQYQRATHRDQPIHESDLRD
>Mature_367_residues
SLLLEPFTLRQLTLSNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVFTEATAITADGRITAEDLGLWNDEQILP
LQRITRFINAQGAVAGIQLAHAGRKASTHRPWIGKHGSVKPEDGGWIPVGPSPIAFDPQHTQPKQLDEGQIAQVIQDFVA
AAKRALTAGFSVVEVHAAHGYLLHQFLSPLSNQRRDQYGGSFENRIRLVLQVTEAVRAVWPEELPVFVRLSATDWVEDGW
NPDETVELARRLKALGADLIDVSSGGTAVNAEIPVGPGYQTRFAERVRKESGIATGTVGMITEPAQAEHILRTCQADIIF
LARELLRDPYWPLHADDDLGGRKAVWPAQYQRATHRDQPIHESDLRD

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=269, Percent_Identity=34.2007434944238, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789463, Length=332, Percent_Identity=28.9156626506024, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17559802, Length=180, Percent_Identity=37.2222222222222, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=182, Percent_Identity=34.0659340659341, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=189, Percent_Identity=34.3915343915344, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=183, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=193, Percent_Identity=33.6787564766839, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=261, Percent_Identity=29.1187739463602, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=284, Percent_Identity=29.2253521126761, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=247, Percent_Identity=29.9595141700405, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321973, Length=238, Percent_Identity=31.5126050420168, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40446; Mature: 40315

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLEPFTLRQLTLSNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVFTEATAI
CCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECEEE
TADGRITAEDLGLWNDEQILPLQRITRFINAQGAVAGIQLAHAGRKASTHRPWIGKHGSV
ECCCEEEHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
KPEDGGWIPVGPSPIAFDPQHTQPKQLDEGQIAQVIQDFVAAAKRALTAGFSVVEVHAAH
CCCCCCEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GYLLHQFLSPLSNQRRDQYGGSFENRIRLVLQVTEAVRAVWPEELPVFVRLSATDWVEDG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCC
WNPDETVELARRLKALGADLIDVSSGGTAVNAEIPVGPGYQTRFAERVRKESGIATGTVG
CCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
MITEPAQAEHILRTCQADIIFLARELLRDPYWPLHADDDLGGRKAVWPAQYQRATHRDQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IHESDLRD
CCHHCCCC
>Mature Secondary Structure 
SLLLEPFTLRQLTLSNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVFTEATAI
CCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECEEE
TADGRITAEDLGLWNDEQILPLQRITRFINAQGAVAGIQLAHAGRKASTHRPWIGKHGSV
ECCCEEEHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
KPEDGGWIPVGPSPIAFDPQHTQPKQLDEGQIAQVIQDFVAAAKRALTAGFSVVEVHAAH
CCCCCCEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GYLLHQFLSPLSNQRRDQYGGSFENRIRLVLQVTEAVRAVWPEELPVFVRLSATDWVEDG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCC
WNPDETVELARRLKALGADLIDVSSGGTAVNAEIPVGPGYQTRFAERVRKESGIATGTVG
CCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
MITEPAQAEHILRTCQADIIFLARELLRDPYWPLHADDDLGGRKAVWPAQYQRATHRDQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
IHESDLRD
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA