Click here to switch to the map view.

The map label for this gene is bvgS [H]

Identifier: 77457256

GI number: 77457256

Start: 1193626

End: 1195014

Strand: Direct

Name: bvgS [H]

Synonym: Pfl01_1029

Alternate gene names: 77457256

Gene position: 1193626-1195014 (Clockwise)

Preceding gene: 77457255

Following gene: 77457258

Centisome position: 18.54

GC content: 59.04

Gene sequence:

>1389_bases
ATGACGAAGGATGTGGCAATGCGGTTTTTTTCAGGATTGAAACCAGCCCTGTGCTGGTGGTTTTTGTTGGGAGGCTTCGG
GCTGGCGCAGTGGGCCGAAGCTGCCCATCTGGCGAAGCATTCCGAGGCGCTGGAGAGTGTTCAGCTTATCGAGCTGGATG
AACATGAGCGTCAGTGGATTCGAGAGAATCCCCGAGTGGTCGTTGCCTCGGTGCAATACCCGTTGTATCTGTTTCAGGAC
GAGCATGGCCAGTGGAGCGGCTTGAACAACGATGTGCTCAAGCACATCAGCACCATGACCGGATTGCAGTTCGTCCATCA
GGAGTCGTTTTCCACCGATCACATGCTGGAACGGCTCCAGAGTGGCGTGGCCGACATCAGCACGACGTTGGCAATGAATG
ACGAGCGCAAGGTATTTCTGGACTTCAGTCACGCGTTCGGTGGTGCCGGATGGGTGTTCGTCGGTCATTCGGACGAGCCG
GCGATACAGTCGCTCGCAACGCTGACCAAGCGGGTACTGGTGCTGCCGGCCAGGCATGCGCTTGAGGACAGCATCCGACG
CGACTACCCGTCGATCCAGATCCGCTCGGTCAAGACCTATGCCGAGGCTCGGGCACTGGTCGAGAGCGGCGAGGCCTACG
CCACTATCGAAAACGAGATCGGGGCTCAGCTGTTTCCCTCAGGGCTGCTCAAGGTCGGTGGTCTCGTGGAGGGCAAGTGG
GAGGCCGATCATCTGGCCGTCCGCAAGGGAATGCCTGAACTGCTGAGCATCCTCAACAAGGCATTGGGTGCTTTCTCGGG
GGCTGAACTGCGGGCCATGCGTCTTAAATGGCTGGGAGGCGTTTCCCCTGTGCCCGCACCCTCGATCGGGGCACGCATGA
TCGAGTGGGGCTGCTGGGCAATGGGCGCTGTGGGTTTGTTTGGGCTGCTGTCGCTATTGTGGAACCGTCGACTGGCGGCG
CAAGTAAAACAGCGACGTGAGGCGGAAAAGGATCTGGGCGATCAACTGGCCTTTCAACACGCACTGATCGATGCGATGCC
CGACCCCGTGTTCGTGCGCGATCTGCAGGGACGCTTGATCATGTGCAACCGCAGTTATGAGGATGCTCTTTCGGTCCGGC
AGGAGCAGGTGCTGGGCCGCATGCTGTTCGAGTTTGATGCACTTCCGCAGGCTACGGCATTGATGCTGCACGACGAATTC
ATTGCGCAGCTGGGTACGCGTAAAACACGCTTCAGCAAACGACAGTTGATGTTCAAGAGCGGCCCCCGTCAGATCTATCA
GTGGACGGTGCCGTTTTACAGTGCCGACGGAAAGCTGCGTGGCCTGCTCGGAGGCTGGACGGACATCACCGAGCGGCGGA
AGGAGAGCGGGTGTCGATGTCTGCATTAA

Upstream 100 bases:

>100_bases
CGCGCAAAGCTGTCACATTTTGAAGCCCGTCTCCTGACGGGCTTTCTTGTTTTTGCATGCCACACTGCGCGCGTTTCGCC
CACCAAGGACGGGCGAGTCG

Downstream 100 bases:

>100_bases
AGATGGGAAAAGTCCTATAAGCAGCGATTCCTTTTCTGATGGGAGGCTTAGGACCACTGCCCTAGAGTGACAGGCCACTG
CGGCGTGAATCCGCGATTGT

Product: sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTKDVAMRFFSGLKPALCWWFLLGGFGLAQWAEAAHLAKHSEALESVQLIELDEHERQWIRENPRVVVASVQYPLYLFQD
EHGQWSGLNNDVLKHISTMTGLQFVHQESFSTDHMLERLQSGVADISTTLAMNDERKVFLDFSHAFGGAGWVFVGHSDEP
AIQSLATLTKRVLVLPARHALEDSIRRDYPSIQIRSVKTYAEARALVESGEAYATIENEIGAQLFPSGLLKVGGLVEGKW
EADHLAVRKGMPELLSILNKALGAFSGAELRAMRLKWLGGVSPVPAPSIGARMIEWGCWAMGAVGLFGLLSLLWNRRLAA
QVKQRREAEKDLGDQLAFQHALIDAMPDPVFVRDLQGRLIMCNRSYEDALSVRQEQVLGRMLFEFDALPQATALMLHDEF
IAQLGTRKTRFSKRQLMFKSGPRQIYQWTVPFYSADGKLRGLLGGWTDITERRKESGCRCLH

Sequences:

>Translated_462_residues
MTKDVAMRFFSGLKPALCWWFLLGGFGLAQWAEAAHLAKHSEALESVQLIELDEHERQWIRENPRVVVASVQYPLYLFQD
EHGQWSGLNNDVLKHISTMTGLQFVHQESFSTDHMLERLQSGVADISTTLAMNDERKVFLDFSHAFGGAGWVFVGHSDEP
AIQSLATLTKRVLVLPARHALEDSIRRDYPSIQIRSVKTYAEARALVESGEAYATIENEIGAQLFPSGLLKVGGLVEGKW
EADHLAVRKGMPELLSILNKALGAFSGAELRAMRLKWLGGVSPVPAPSIGARMIEWGCWAMGAVGLFGLLSLLWNRRLAA
QVKQRREAEKDLGDQLAFQHALIDAMPDPVFVRDLQGRLIMCNRSYEDALSVRQEQVLGRMLFEFDALPQATALMLHDEF
IAQLGTRKTRFSKRQLMFKSGPRQIYQWTVPFYSADGKLRGLLGGWTDITERRKESGCRCLH
>Mature_461_residues
TKDVAMRFFSGLKPALCWWFLLGGFGLAQWAEAAHLAKHSEALESVQLIELDEHERQWIRENPRVVVASVQYPLYLFQDE
HGQWSGLNNDVLKHISTMTGLQFVHQESFSTDHMLERLQSGVADISTTLAMNDERKVFLDFSHAFGGAGWVFVGHSDEPA
IQSLATLTKRVLVLPARHALEDSIRRDYPSIQIRSVKTYAEARALVESGEAYATIENEIGAQLFPSGLLKVGGLVEGKWE
ADHLAVRKGMPELLSILNKALGAFSGAELRAMRLKWLGGVSPVPAPSIGARMIEWGCWAMGAVGLFGLLSLLWNRRLAAQ
VKQRREAEKDLGDQLAFQHALIDAMPDPVFVRDLQGRLIMCNRSYEDALSVRQEQVLGRMLFEFDALPQATALMLHDEFI
AQLGTRKTRFSKRQLMFKSGPRQIYQWTVPFYSADGKLRGLLGGWTDITERRKESGCRCLH

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=419, Percent_Identity=26.7303102625298, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51919; Mature: 51788

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDVAMRFFSGLKPALCWWFLLGGFGLAQWAEAAHLAKHSEALESVQLIELDEHERQWI
CCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
RENPRVVVASVQYPLYLFQDEHGQWSGLNNDVLKHISTMTGLQFVHQESFSTDHMLERLQ
HCCCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SGVADISTTLAMNDERKVFLDFSHAFGGAGWVFVGHSDEPAIQSLATLTKRVLVLPARHA
HHHHHHHHHEEECCCCEEEEEEHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHH
LEDSIRRDYPSIQIRSVKTYAEARALVESGEAYATIENEIGAQLFPSGLLKVGGLVEGKW
HHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHCCHHHCCHHHHHHCCCCCCCC
EADHLAVRKGMPELLSILNKALGAFSGAELRAMRLKWLGGVSPVPAPSIGARMIEWGCWA
CHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
MGAVGLFGLLSLLWNRRLAAQVKQRREAEKDLGDQLAFQHALIDAMPDPVFVRDLQGRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEE
MCNRSYEDALSVRQEQVLGRMLFEFDALPQATALMLHDEFIAQLGTRKTRFSKRQLMFKS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GPRQIYQWTVPFYSADGKLRGLLGGWTDITERRKESGCRCLH
CCCEEEEEECCEECCCCCEEHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKDVAMRFFSGLKPALCWWFLLGGFGLAQWAEAAHLAKHSEALESVQLIELDEHERQWI
CHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHH
RENPRVVVASVQYPLYLFQDEHGQWSGLNNDVLKHISTMTGLQFVHQESFSTDHMLERLQ
HCCCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SGVADISTTLAMNDERKVFLDFSHAFGGAGWVFVGHSDEPAIQSLATLTKRVLVLPARHA
HHHHHHHHHEEECCCCEEEEEEHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHH
LEDSIRRDYPSIQIRSVKTYAEARALVESGEAYATIENEIGAQLFPSGLLKVGGLVEGKW
HHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHCCHHHCCHHHHHHCCCCCCCC
EADHLAVRKGMPELLSILNKALGAFSGAELRAMRLKWLGGVSPVPAPSIGARMIEWGCWA
CHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
MGAVGLFGLLSLLWNRRLAAQVKQRREAEKDLGDQLAFQHALIDAMPDPVFVRDLQGRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEE
MCNRSYEDALSVRQEQVLGRMLFEFDALPQATALMLHDEFIAQLGTRKTRFSKRQLMFKS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GPRQIYQWTVPFYSADGKLRGLLGGWTDITERRKESGCRCLH
CCCEEEEEECCEECCCCCEEHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]