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The map label for this gene is nudL [H]

Identifier: 77457237

GI number: 77457237

Start: 1175748

End: 1176347

Strand: Direct

Name: nudL [H]

Synonym: Pfl01_1010

Alternate gene names: 77457237

Gene position: 1175748-1176347 (Clockwise)

Preceding gene: 77457229

Following gene: 77457238

Centisome position: 18.26

GC content: 60.67

Gene sequence:

>600_bases
ATGCTGGACGAGCTACTGCACCGGGTAAGCAATCACACGCCGCGCACGCTGGAGACCGACACGCGTTTCCCCGAGGCCGC
TGTCCTGGTGCCGATTACTCGCAGTGACGAACCCGAACTTGTCCTCACCCTGCGCGCCAGCGGGCTCTCGACCCACGGCG
GCGAAGTCGCCTTCCCCGGTGGGCGACGCGATCCCGAGGACCCGGATCTGGTGTTCACCGCCCTGCGTGAAGCCGAAGAG
GAAATCGGCCTGCCGCCGGGACTGGTCGAAGTGATCGGTCCGCTCAGCCCGCTGATTTCCCTGCATGGCATCAAGGTCAC
GCCGTATGTCGGGGTGATTCCGGATTTTGTCGAATACCAGGCCAATGATGCCGAGATTGCTGCGGTGTTCAGTGTGCCGC
TGGAGTTCTTCCGCAAGGATCCGCGCGAACACACTCATCGCATCGACTACCAGGGTCGCAGTTGGTACGTGCCGAGCTAC
CGTTACGGTGACTACAAGATCTGGGGGCTGACGGCGATCATGATCGTCGAGTTGATCAACCTGCTCTATGACGCCAAAAT
CAGCCTGCATCAGCCGCCTAAAAGCTTTATCAACACCTGA

Upstream 100 bases:

>100_bases
GTCGGCAAGTTGTCGTTTCGCGACATGACGGCCGTTCGGGGCTTGGGCGGTCGCAATGATTGGTGCATGATGCAGGGTAA
GGCACCGATCGAGAACACTT

Downstream 100 bases:

>100_bases
AGCCATCGCTCGAATGGCCAGCCATCGTGAGCCCTGAGGAAAACAAGATGAAATACCGCCTGGGCGACGCCCGCGTCGAA
ACCCATCCGCAGAGCTGGGT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLDELLHRVSNHTPRTLETDTRFPEAAVLVPITRSDEPELVLTLRASGLSTHGGEVAFPGGRRDPEDPDLVFTALREAEE
EIGLPPGLVEVIGPLSPLISLHGIKVTPYVGVIPDFVEYQANDAEIAAVFSVPLEFFRKDPREHTHRIDYQGRSWYVPSY
RYGDYKIWGLTAIMIVELINLLYDAKISLHQPPKSFINT

Sequences:

>Translated_199_residues
MLDELLHRVSNHTPRTLETDTRFPEAAVLVPITRSDEPELVLTLRASGLSTHGGEVAFPGGRRDPEDPDLVFTALREAEE
EIGLPPGLVEVIGPLSPLISLHGIKVTPYVGVIPDFVEYQANDAEIAAVFSVPLEFFRKDPREHTHRIDYQGRSWYVPSY
RYGDYKIWGLTAIMIVELINLLYDAKISLHQPPKSFINT
>Mature_199_residues
MLDELLHRVSNHTPRTLETDTRFPEAAVLVPITRSDEPELVLTLRASGLSTHGGEVAFPGGRRDPEDPDLVFTALREAEE
EIGLPPGLVEVIGPLSPLISLHGIKVTPYVGVIPDFVEYQANDAEIAAVFSVPLEFFRKDPREHTHRIDYQGRSWYVPSY
RYGDYKIWGLTAIMIVELINLLYDAKISLHQPPKSFINT

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=171, Percent_Identity=35.0877192982456, Blast_Score=98, Evalue=6e-21,
Organism=Escherichia coli, GI1788115, Length=177, Percent_Identity=43.5028248587571, Blast_Score=107, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17536993, Length=174, Percent_Identity=32.183908045977, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17510677, Length=155, Percent_Identity=33.5483870967742, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI18859683, Length=177, Percent_Identity=35.5932203389831, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22358; Mature: 22358

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDELLHRVSNHTPRTLETDTRFPEAAVLVPITRSDEPELVLTLRASGLSTHGGEVAFPG
CHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCEEECCC
GRRDPEDPDLVFTALREAEEEIGLPPGLVEVIGPLSPLISLHGIKVTPYVGVIPDFVEYQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHC
ANDAEIAAVFSVPLEFFRKDPREHTHRIDYQGRSWYVPSYRYGDYKIWGLTAIMIVELIN
CCCCCEEHHHHHHHHHHHCCCHHHHCCCCCCCCEEECCCEEECCEEEHHHHHHHHHHHHH
LLYDAKISLHQPPKSFINT
HHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MLDELLHRVSNHTPRTLETDTRFPEAAVLVPITRSDEPELVLTLRASGLSTHGGEVAFPG
CHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCEEECCC
GRRDPEDPDLVFTALREAEEEIGLPPGLVEVIGPLSPLISLHGIKVTPYVGVIPDFVEYQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHC
ANDAEIAAVFSVPLEFFRKDPREHTHRIDYQGRSWYVPSYRYGDYKIWGLTAIMIVELIN
CCCCCEEHHHHHHHHHHHCCCHHHHCCCCCCCCEEECCCEEECCEEEHHHHHHHHHHHHH
LLYDAKISLHQPPKSFINT
HHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA