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The map label for this gene is yhcA [H]

Identifier: 77457170

GI number: 77457170

Start: 1094928

End: 1096298

Strand: Reverse

Name: yhcA [H]

Synonym: Pfl01_0943

Alternate gene names: 77457170

Gene position: 1096298-1094928 (Counterclockwise)

Preceding gene: 77457172

Following gene: 77457169

Centisome position: 17.03

GC content: 61.93

Gene sequence:

>1371_bases
ATGGCCTATCGCTCGAAAGTCGCGCTGGTGTATCTGTTGGGGTTCGCCCTCGACCTGCTGAACATGTTCGCCGCGAGCAT
CGCCTACCCGGACATCGCCGCGCAGTTGCGCGCTTCGGTGACGCAACTGGCGTGGATCACCAACGCCTACATGCTCGGGC
TGACGCTGATCATTCCGATGAGCGTTTGGCTCGCGGCAAAGGTTGGCGAGCGGCGGCTGATCCTCGGTTCGCTGCTGGTG
TTCGGGATTGCCTCCGGGCTTATCGCTCAGGCGAGCTCGATTGAAAGTCTGATCGGCTGGCGACTGCTGCAAGGGCTGGG
TGGCGGGTTGCTGCTTCCGGTTGGTCAGGCGCTGGCCTATCGAGAGTTTCCGGCGACACAACGCGCGCACTTCACCGGTG
TGGTGTTGCTGGTGGCGCTGATGGTGCCGGCGCTGTCGCCGGCGGCTGGAGGCTTGATCGTTGAGGCATTGTCGTGGCGC
TGGATTTTCCTTCTGAACATGCCGGTGGCGCTTTTCGCTTTCGGTCTGGGCCTGCGCTGGTTGAAAGCGGATCAGGCTGC
GAGTGAACGCCCGAAACTGGACGCTCGCGGCCTGCTGCTGGCGGTGGCCGCGCTGAGTCTGTTGCTGATGGCCGTCAGTC
TGGCGAGCGCCCCCGCAACCCGACATCTCGCCGGCGGTGTCCTGCTGCTCAGCGTCATCACCTTGTGGATCTACCTGCGC
GATGGCTGGAACAAACCGGGTGCAGTCCTTGATCTGCAACTGATCAAGAACCCGTCATTGCGCCTGGCGATGCTGATCTA
CCTGTTCGTGCCCGGCATCTTTACCGGCACCAACATGATTGCCGTGTTGTACCTGCACGATCTCGGTTTCGGCGCAGCAC
AAACCGGGGCGCTGATGCTGGCCTGGGCGGCGGCCTCGGGCGTGGCGATCATGCTGGGCAAACGCAGCTTCAACCGGATC
GGCCCCAAGCCATTGCTGATCGCCGGCATGTTGCTGCAATGCCTTGGCATCGTCGTGCTGATGCAGATCGATCAACCCGC
CAGCGGCCCGTTGATCCTCGCCTATGCCCTGATGGGGTTGGGCGGCAGCCTGTGCAGCGTCACCGCGCAGACCCTGGCAT
TTGTCGGCATCACGCCGGAAAAAATGGGTCACTCCAGCGCTCTGTGGAATATCAATCGCCAACTCGGTTTCTGCCTCGGC
GCGGCACTGCTCAGCTCCCTGTTGGACGCTTTGGGCGCCAACGGATTCAAATACTGCTTTCTCGCCGCTGCACTGCTCAC
GCTGTTGCCGATGGCCGCCGTGTTGCGTTTCGACTCGACAAAAGTGCTAGCCCTTCTGCGCTCAACTCACCTTCAGGAAA
AATCCACATGA

Upstream 100 bases:

>100_bases
CTCCGGTGTCAAAATAATTTTGACAAACTAGCAGCCAAACCAGCGTATTTCTATTACCGCCAGCGCCCTACCCTGCACGC
CTCATCACAGGGAAGCTGCC

Downstream 100 bases:

>100_bases
CTGACTACGCCGACTATTTTGACGAAGTGATCCAGGCCCATGAGGCCATCGAACGATGGTTTGCCGTTGACGAGGAAGAG
GCAGCGCTTGAACGATTGCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAYRSKVALVYLLGFALDLLNMFAASIAYPDIAAQLRASVTQLAWITNAYMLGLTLIIPMSVWLAAKVGERRLILGSLLV
FGIASGLIAQASSIESLIGWRLLQGLGGGLLLPVGQALAYREFPATQRAHFTGVVLLVALMVPALSPAAGGLIVEALSWR
WIFLLNMPVALFAFGLGLRWLKADQAASERPKLDARGLLLAVAALSLLLMAVSLASAPATRHLAGGVLLLSVITLWIYLR
DGWNKPGAVLDLQLIKNPSLRLAMLIYLFVPGIFTGTNMIAVLYLHDLGFGAAQTGALMLAWAAASGVAIMLGKRSFNRI
GPKPLLIAGMLLQCLGIVVLMQIDQPASGPLILAYALMGLGGSLCSVTAQTLAFVGITPEKMGHSSALWNINRQLGFCLG
AALLSSLLDALGANGFKYCFLAAALLTLLPMAAVLRFDSTKVLALLRSTHLQEKST

Sequences:

>Translated_456_residues
MAYRSKVALVYLLGFALDLLNMFAASIAYPDIAAQLRASVTQLAWITNAYMLGLTLIIPMSVWLAAKVGERRLILGSLLV
FGIASGLIAQASSIESLIGWRLLQGLGGGLLLPVGQALAYREFPATQRAHFTGVVLLVALMVPALSPAAGGLIVEALSWR
WIFLLNMPVALFAFGLGLRWLKADQAASERPKLDARGLLLAVAALSLLLMAVSLASAPATRHLAGGVLLLSVITLWIYLR
DGWNKPGAVLDLQLIKNPSLRLAMLIYLFVPGIFTGTNMIAVLYLHDLGFGAAQTGALMLAWAAASGVAIMLGKRSFNRI
GPKPLLIAGMLLQCLGIVVLMQIDQPASGPLILAYALMGLGGSLCSVTAQTLAFVGITPEKMGHSSALWNINRQLGFCLG
AALLSSLLDALGANGFKYCFLAAALLTLLPMAAVLRFDSTKVLALLRSTHLQEKST
>Mature_455_residues
AYRSKVALVYLLGFALDLLNMFAASIAYPDIAAQLRASVTQLAWITNAYMLGLTLIIPMSVWLAAKVGERRLILGSLLVF
GIASGLIAQASSIESLIGWRLLQGLGGGLLLPVGQALAYREFPATQRAHFTGVVLLVALMVPALSPAAGGLIVEALSWRW
IFLLNMPVALFAFGLGLRWLKADQAASERPKLDARGLLLAVAALSLLLMAVSLASAPATRHLAGGVLLLSVITLWIYLRD
GWNKPGAVLDLQLIKNPSLRLAMLIYLFVPGIFTGTNMIAVLYLHDLGFGAAQTGALMLAWAAASGVAIMLGKRSFNRIG
PKPLLIAGMLLQCLGIVVLMQIDQPASGPLILAYALMGLGGSLCSVTAQTLAFVGITPEKMGHSSALWNINRQLGFCLGA
ALLSSLLDALGANGFKYCFLAAALLTLLPMAAVLRFDSTKVLALLRSTHLQEKST

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=420, Percent_Identity=26.6666666666667, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788710, Length=408, Percent_Identity=24.7549019607843, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790195, Length=461, Percent_Identity=24.5119305856833, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789042, Length=186, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788392, Length=443, Percent_Identity=26.410835214447, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48355; Mature: 48224

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRSKVALVYLLGFALDLLNMFAASIAYPDIAAQLRASVTQLAWITNAYMLGLTLIIPM
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVWLAAKVGERRLILGSLLVFGIASGLIAQASSIESLIGWRLLQGLGGGLLLPVGQALAY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
REFPATQRAHFTGVVLLVALMVPALSPAAGGLIVEALSWRWIFLLNMPVALFAFGLGLRW
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LKADQAASERPKLDARGLLLAVAALSLLLMAVSLASAPATRHLAGGVLLLSVITLWIYLR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGWNKPGAVLDLQLIKNPSLRLAMLIYLFVPGIFTGTNMIAVLYLHDLGFGAAQTGALML
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHCCCHHHHHHHHHHCCCCCHHHCHHHE
AWAAASGVAIMLGKRSFNRIGPKPLLIAGMLLQCLGIVVLMQIDQPASGPLILAYALMGL
EEHHHCCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GGSLCSVTAQTLAFVGITPEKMGHSSALWNINRQLGFCLGAALLSSLLDALGANGFKYCF
CCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAAALLTLLPMAAVLRFDSTKVLALLRSTHLQEKST
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AYRSKVALVYLLGFALDLLNMFAASIAYPDIAAQLRASVTQLAWITNAYMLGLTLIIPM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVWLAAKVGERRLILGSLLVFGIASGLIAQASSIESLIGWRLLQGLGGGLLLPVGQALAY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
REFPATQRAHFTGVVLLVALMVPALSPAAGGLIVEALSWRWIFLLNMPVALFAFGLGLRW
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LKADQAASERPKLDARGLLLAVAALSLLLMAVSLASAPATRHLAGGVLLLSVITLWIYLR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGWNKPGAVLDLQLIKNPSLRLAMLIYLFVPGIFTGTNMIAVLYLHDLGFGAAQTGALML
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHCCCHHHHHHHHHHCCCCCHHHCHHHE
AWAAASGVAIMLGKRSFNRIGPKPLLIAGMLLQCLGIVVLMQIDQPASGPLILAYALMGL
EEHHHCCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GGSLCSVTAQTLAFVGITPEKMGHSSALWNINRQLGFCLGAALLSSLLDALGANGFKYCF
CCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAAALLTLLPMAAVLRFDSTKVLALLRSTHLQEKST
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]