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The map label for this gene is yhcS [C]

Identifier: 77457164

GI number: 77457164

Start: 1088442

End: 1089410

Strand: Reverse

Name: yhcS [C]

Synonym: Pfl01_0937

Alternate gene names: 77457164

Gene position: 1089410-1088442 (Counterclockwise)

Preceding gene: 255961282

Following gene: 77457163

Centisome position: 16.92

GC content: 63.16

Gene sequence:

>969_bases
ATGGACACTTTGCAAAACATGCGCGCCTTCAGTTGTGTAGCGGAAGCCGGCAGCTTCACCGCCGCTGCCGTGCAGCTCGA
CACCACCACCGCCAACGTCTCGCGCGCGGTCTCCAACCTTGAGGCCCACCTGCAAACCCGCCTGCTGAATCGCACGACCC
GCCGCATCGCGCTCACCGAAGCCGGCAAGCGCTACCTGCTGCGCTGCGAGCAGATCCTCGCCTACGTCGAAGAGGCCGAA
GCCGAAGCCAGCGAAGCCCACGCGCGCCCGGCCGGACAATTGAAAGTGCACACCATGACCGGCATCGGCCAGCACTTCGT
GATCGACGCCATCGCCCGTTATCGCAAGACCCACCCGGACGTGACCTTCGACCTGACCATGGCCAACCGCGTGCCGGACC
TGCTCGACGAAGGCTACGACGTGTCCATCGTCCTGGCCCGCGAATTGCCGGACTCGGGCTTCGTCTCGCAACGTCTGGGC
ATCACCTACAGCATCGTCTGCGCCTCCCCGGCCTACGTAAAAGCCAACGGCTGCGCACAAAAACCCAGCGACCTGCTGAA
CCACGCCTGCCTGCGCCTGGTGAGCCCGGTGATCCCCCTGGAAAAATGGGCCTTCGACGGCCCTGACGGCCAGGAAATGG
TCACCATCAACAGCTCGCCTTTCCTGGTGAACTCCGCCGACGCGATGAAAAGCGCGATCACCAGTGGCATGGGCGTCGGC
GTTTTGCCGGTGTACGCCGCGATTGAAGGCTTGCGCAACGGCTCGTTGGTGCGGGTCATGCCGAACTATCGCTCGCAGGA
ACTGAACCTGTACGCGATCTATCCGTCGCGGCAGTATCTGGATGCGAAGATCAAGACCTGGGTTGAATACCTGCGTGGGT
CGTTGCCGGAGATATTGGCGGGGCATCAGGCAGAGTTGGCGGCTTATGAGCTGAGTGGGAGCCTGGCGGGGGTGCGAGTG
GCGAATTGA

Upstream 100 bases:

>100_bases
CTGTGAATCTTTGTTACCGTTAACGAGATAATCCCTTGGTCGGGGGTCTCAGCCCCTGAAACTTCGTGTCACAATTTGCC
ATCTCCCTTGAGAGCACCCC

Downstream 100 bases:

>100_bases
GTTGGCCGGTCTGAAAAATGGGGGAATACGGAGGGCGCCAACCCCTCACCCTAGCCCTCTCCCAAGGGAGAGGGGACCGA
CCGAGTTGTTTGGGAGAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDTLQNMRAFSCVAEAGSFTAAAVQLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGKRYLLRCEQILAYVEEAE
AEASEAHARPAGQLKVHTMTGIGQHFVIDAIARYRKTHPDVTFDLTMANRVPDLLDEGYDVSIVLARELPDSGFVSQRLG
ITYSIVCASPAYVKANGCAQKPSDLLNHACLRLVSPVIPLEKWAFDGPDGQEMVTINSSPFLVNSADAMKSAITSGMGVG
VLPVYAAIEGLRNGSLVRVMPNYRSQELNLYAIYPSRQYLDAKIKTWVEYLRGSLPEILAGHQAELAAYELSGSLAGVRV
AN

Sequences:

>Translated_322_residues
MDTLQNMRAFSCVAEAGSFTAAAVQLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGKRYLLRCEQILAYVEEAE
AEASEAHARPAGQLKVHTMTGIGQHFVIDAIARYRKTHPDVTFDLTMANRVPDLLDEGYDVSIVLARELPDSGFVSQRLG
ITYSIVCASPAYVKANGCAQKPSDLLNHACLRLVSPVIPLEKWAFDGPDGQEMVTINSSPFLVNSADAMKSAITSGMGVG
VLPVYAAIEGLRNGSLVRVMPNYRSQELNLYAIYPSRQYLDAKIKTWVEYLRGSLPEILAGHQAELAAYELSGSLAGVRV
AN
>Mature_322_residues
MDTLQNMRAFSCVAEAGSFTAAAVQLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTEAGKRYLLRCEQILAYVEEAE
AEASEAHARPAGQLKVHTMTGIGQHFVIDAIARYRKTHPDVTFDLTMANRVPDLLDEGYDVSIVLARELPDSGFVSQRLG
ITYSIVCASPAYVKANGCAQKPSDLLNHACLRLVSPVIPLEKWAFDGPDGQEMVTINSSPFLVNSADAMKSAITSGMGVG
VLPVYAAIEGLRNGSLVRVMPNYRSQELNLYAIYPSRQYLDAKIKTWVEYLRGSLPEILAGHQAELAAYELSGSLAGVRV
AN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=31.8791946308725, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=30.718954248366, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=33.5616438356164, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=29.2517006802721, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=27.7777777777778, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=25.7731958762887, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=25.5972696245734, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=26.5625, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787879, Length=153, Percent_Identity=32.0261437908497, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=22.7586206896552, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082132, Length=298, Percent_Identity=23.489932885906, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788481, Length=305, Percent_Identity=23.2786885245902, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=118, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790011, Length=286, Percent_Identity=22.7272727272727, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=30.8943089430894, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35059; Mature: 35059

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRAFSCVAEAGSFTAAAVQLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTE
CCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHH
AGKRYLLRCEQILAYVEEAEAEASEAHARPAGQLKVHTMTGIGQHFVIDAIARYRKTHPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
VTFDLTMANRVPDLLDEGYDVSIVLARELPDSGFVSQRLGITYSIVCASPAYVKANGCAQ
EEEEEEEHHCCHHHHHCCCCEEEEEEECCCCCCCHHHHCCCEEEEEECCCCEEECCCCCC
KPSDLLNHACLRLVSPVIPLEKWAFDGPDGQEMVTINSSPFLVNSADAMKSAITSGMGVG
CHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCCEEECHHHHHHHHHCCCCCH
VLPVYAAIEGLRNGSLVRVMPNYRSQELNLYAIYPSRQYLDAKIKTWVEYLRGSLPEILA
HHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHC
GHQAELAAYELSGSLAGVRVAN
CCCHHHEEEEECCCCCCEEECC
>Mature Secondary Structure
MDTLQNMRAFSCVAEAGSFTAAAVQLDTTTANVSRAVSNLEAHLQTRLLNRTTRRIALTE
CCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHH
AGKRYLLRCEQILAYVEEAEAEASEAHARPAGQLKVHTMTGIGQHFVIDAIARYRKTHPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
VTFDLTMANRVPDLLDEGYDVSIVLARELPDSGFVSQRLGITYSIVCASPAYVKANGCAQ
EEEEEEEHHCCHHHHHCCCCEEEEEEECCCCCCCHHHHCCCEEEEEECCCCEEECCCCCC
KPSDLLNHACLRLVSPVIPLEKWAFDGPDGQEMVTINSSPFLVNSADAMKSAITSGMGVG
CHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCCEEECHHHHHHHHHCCCCCH
VLPVYAAIEGLRNGSLVRVMPNYRSQELNLYAIYPSRQYLDAKIKTWVEYLRGSLPEILA
HHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHC
GHQAELAAYELSGSLAGVRVAN
CCCHHHEEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]