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The map label for this gene is yrbG [H]

Identifier: 77457060

GI number: 77457060

Start: 981213

End: 982274

Strand: Reverse

Name: yrbG [H]

Synonym: Pfl01_0833

Alternate gene names: 77457060

Gene position: 982274-981213 (Counterclockwise)

Preceding gene: 77457061

Following gene: 77457059

Centisome position: 15.26

GC content: 65.44

Gene sequence:

>1062_bases
GTGATCGAATTGCTCAGCGGGCTGTTCCTGCTGATCGCCGGCGCCGAGCTGATGGTGCGCGCCGCCGTGCGCCTGGCCGC
GCGTCTGCATGTCCGACCGCTGATCATCGGCCTGACCATCGTCGCCCTCGGCAGCAGCGCTCCGCAAATGGCCGTCAGCC
TGCAAGCCGTACAGGCGCACACGCCGGACATCGCCGTCAGCAGCGTGATCGGCAGCAGCATTTTCAACATTCTCGTCACC
CTCGGCCTGTCGGCGCTGATCATTCCGCTGCGGGTATCGCGGCAATTGGTGCGCCTCGACATTCCACTGATGATCGGTGC
CAGCCTGCTGGTGTTCGTCCTGGCATGGAATGAAGAGCTCGGGCGCTTCGACGGCATTCTGTTGCTCGGCGCCCTCGCCC
TGTATCTCGGATTATTGCTGCGCCAGTCGCGGCACTCGGCCCGCCCGCACTCCGATCAACCCCACGATCCGCAGGCCCCA
TGGTTCACCAGCCTGCTGATGATTGTCGGCGGTCTGGGCATGCTGGTGTTCGCCGGGCATCTGCTACTGGGGGCGGCCGT
GGTGGTGGCCACCGACCTGGGGTTCTCCGAGCGGGTGATCGGCCTGACCGTGGTCGCGGTCGGCACCTCGCTGCCGGAAC
TCGCCACCTCGCTGATCGCTGCGTTGCGCGGTCAGCGGGACATCGCCGTGGGCAACGTGATCGGTGCCAACCTGTTCAAC
CTGCTTGGGGTGCTGGGCCTCACCGCACTGATCGCGCCGACGCCGCTGTCGGTCTCGCCGAACGCACTGGATTTCGACCT
GCCGGTGATGCTCGGCGTCGCCGCGCTGTGCCTGCCGGTGTTCTATTCCGGTTACCGCGTGACCCGGGCCGAAGGCCTGT
TGCTGCTGGGTTTGTACCTGGCGTACGGGCTGCACGTGGTGTCGTTCACCACCGGCATGCCACTGGCCGGCAAACTCGAG
CGATTGATGCTGTTTTATGTGCTGCCGACGCTGCTGGCGTTTCTGTTTTTCACGTCCGTGCGCGCCTGGCGCCGCCAACA
CCACAAGAGGGATATGCCATGA

Upstream 100 bases:

>100_bases
GGTATGCTGCGCAGTGGAACCGCCCGCGTTCGGGTCCAGGCCCTCGACGACTGATGGAGCGTCCACTATTTTCGGACTGA
CCGACTTACCCCTGATCAGT

Downstream 100 bases:

>100_bases
CCGAATCGAAGAAATCCGGGGTTGAAGTCCGCCGTCAGGTAATGGGCGACGCGTTTGTCGACCGCGCGCTGGGCAATGCC
ACGGAGTTCACTCAACCCTT

Product: K+-dependent Na+/Ca+ exchanger protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIELLSGLFLLIAGAELMVRAAVRLAARLHVRPLIIGLTIVALGSSAPQMAVSLQAVQAHTPDIAVSSVIGSSIFNILVT
LGLSALIIPLRVSRQLVRLDIPLMIGASLLVFVLAWNEELGRFDGILLLGALALYLGLLLRQSRHSARPHSDQPHDPQAP
WFTSLLMIVGGLGMLVFAGHLLLGAAVVVATDLGFSERVIGLTVVAVGTSLPELATSLIAALRGQRDIAVGNVIGANLFN
LLGVLGLTALIAPTPLSVSPNALDFDLPVMLGVAALCLPVFYSGYRVTRAEGLLLLGLYLAYGLHVVSFTTGMPLAGKLE
RLMLFYVLPTLLAFLFFTSVRAWRRQHHKRDMP

Sequences:

>Translated_353_residues
MIELLSGLFLLIAGAELMVRAAVRLAARLHVRPLIIGLTIVALGSSAPQMAVSLQAVQAHTPDIAVSSVIGSSIFNILVT
LGLSALIIPLRVSRQLVRLDIPLMIGASLLVFVLAWNEELGRFDGILLLGALALYLGLLLRQSRHSARPHSDQPHDPQAP
WFTSLLMIVGGLGMLVFAGHLLLGAAVVVATDLGFSERVIGLTVVAVGTSLPELATSLIAALRGQRDIAVGNVIGANLFN
LLGVLGLTALIAPTPLSVSPNALDFDLPVMLGVAALCLPVFYSGYRVTRAEGLLLLGLYLAYGLHVVSFTTGMPLAGKLE
RLMLFYVLPTLLAFLFFTSVRAWRRQHHKRDMP
>Mature_353_residues
MIELLSGLFLLIAGAELMVRAAVRLAARLHVRPLIIGLTIVALGSSAPQMAVSLQAVQAHTPDIAVSSVIGSSIFNILVT
LGLSALIIPLRVSRQLVRLDIPLMIGASLLVFVLAWNEELGRFDGILLLGALALYLGLLLRQSRHSARPHSDQPHDPQAP
WFTSLLMIVGGLGMLVFAGHLLLGAAVVVATDLGFSERVIGLTVVAVGTSLPELATSLIAALRGQRDIAVGNVIGANLFN
LLGVLGLTALIAPTPLSVSPNALDFDLPVMLGVAALCLPVFYSGYRVTRAEGLLLLGLYLAYGLHVVSFTTGMPLAGKLE
RLMLFYVLPTLLAFLFFTSVRAWRRQHHKRDMP

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300796347, Length=140, Percent_Identity=32.1428571428571, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI9966787, Length=140, Percent_Identity=32.1428571428571, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789587, Length=298, Percent_Identity=37.248322147651, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37674; Mature: 37674

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELLSGLFLLIAGAELMVRAAVRLAARLHVRPLIIGLTIVALGSSAPQMAVSLQAVQAH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPDIAVSSVIGSSIFNILVTLGLSALIIPLRVSRQLVRLDIPLMIGASLLVFVLAWNEEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GRFDGILLLGALALYLGLLLRQSRHSARPHSDQPHDPQAPWFTSLLMIVGGLGMLVFAGH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLLGAAVVVATDLGFSERVIGLTVVAVGTSLPELATSLIAALRGQRDIAVGNVIGANLFN
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
LLGVLGLTALIAPTPLSVSPNALDFDLPVMLGVAALCLPVFYSGYRVTRAEGLLLLGLYL
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
AYGLHVVSFTTGMPLAGKLERLMLFYVLPTLLAFLFFTSVRAWRRQHHKRDMP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIELLSGLFLLIAGAELMVRAAVRLAARLHVRPLIIGLTIVALGSSAPQMAVSLQAVQAH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPDIAVSSVIGSSIFNILVTLGLSALIIPLRVSRQLVRLDIPLMIGASLLVFVLAWNEEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GRFDGILLLGALALYLGLLLRQSRHSARPHSDQPHDPQAPWFTSLLMIVGGLGMLVFAGH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLLGAAVVVATDLGFSERVIGLTVVAVGTSLPELATSLIAALRGQRDIAVGNVIGANLFN
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
LLGVLGLTALIAPTPLSVSPNALDFDLPVMLGVAALCLPVFYSGYRVTRAEGLLLLGLYL
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
AYGLHVVSFTTGMPLAGKLERLMLFYVLPTLLAFLFFTSVRAWRRQHHKRDMP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]