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The map label for this gene is dppA [H]

Identifier: 77457043

GI number: 77457043

Start: 963112

End: 964713

Strand: Reverse

Name: dppA [H]

Synonym: Pfl01_0816

Alternate gene names: 77457043

Gene position: 964713-963112 (Counterclockwise)

Preceding gene: 77457045

Following gene: 77457042

Centisome position: 14.98

GC content: 58.86

Gene sequence:

>1602_bases
ATGGATCGATTCACCCTCAAACCACTTCTAATAACCCTGACCCTGACCGCCATAACCCCAATCGCCAACGCAGCCACAAC
CCTCGTCTACTGCTCCGAAGCCAGCCCCGCAGGCTTCGACCCCAGCCAATACACCAGCGGCACCGACTTCGATGCCTCCG
CCGAAACCGTCTTCAACCGCCTCACCCAATTCAAACGCGGCGGCACCGAAGTCGAACCCGGTCTGGCGACCAAATGGGAC
GTAAGCCCGGACGGCCTCCAGTACACCTTCCACCTGCGCCAAAACGTAAAATTCCACACCACCGACTACTTCACCCCAAC
CCGAACCTTCAACGCCGACGACGTCCTCTTCACCTTCCAGCGCCTGCTCGACCCGGAGAACGCCTTTCGCAAGGCCTACC
CCGCCGAATCCCCGTACTTCACCGACATGGGCCTGAACACCACGATCAAATCCGTGGAAAAACTCGACGACAACACCGTG
CGCTTCAATCTCAACAACGTGGACGCCGCGTTCGTGCAAAACCTCGCCATGAGCTTCGCCTCGGTGCAATCGGCCGAATA
CGCAGCCCAACTACTGAAGGAAGGCCACGCCGCCGACCTCAACCAGAAACCGGTCGGCACCGGCCCGTTCGTGTTCAAGC
GCTATCAGAAGGACGCGCAGATCCGCTACGCAGCGAACAAGGACTACTGGAAACCCGAGGACGTGAAGCTCGATAACCTG
GTGTTCTCGATCACCCCGGACGCCGCCGTACGCCTGCAAAAGCTCAAGACCGGCGAATGCCAGGTCAGCGGTTACCCGCG
CCCCGCCGATATCGAAGTGATGGAAAAAGACCCGAACCTGCGGGTGTTGAAGCAGCCCGGTTTCAACCTCGGCTTCCTCG
CCTACAACACCACCCATCCGCCGCTGGATCAGCTCAAAGTGCGCCAGGCGCTGGACATGGCTATCGACAAACCAGCGATC
ATCAAGGCTGTTTACCAGAGTGCCGGGCAGCTGGCGCAGAACGCCTTGCCGCCAGCGCAATGGTCATTTGATCCGAACAT
AAAAGACGCGCCGCACGACCCGGTAAAAGCCAAGGCGCTACTCAAGGAAGCCAGGGTTGCACCGGGTACAACCATCAACC
TCTGGGCCATGACCGTGCAGCGCGCCTCGAACCCGAATGCGCGGATGTCGGCACAGATGATCCAGCAGGATTGGGAGAAA
ATCGGTATCAAGGCCAACATCGTCAGTTACGAATGGGGCGAGTACATCAAGCGCGCCAAGAACGGCGAGCACGACGCGAT
GATCTACGGCTGGACCGGTGACAACGGCGACCCCGACAACTGGCTGGGCGTGCTTTACAGCTGCGCGGCGGTGAAGGGCA
GCAACTACGCCAAATGGTGCGATCCGGCCTATGACAAGCTGGTACAGCAGGCCAAGGTATCCACCGATAAATCGCAACGG
GTAAAACTGTATCAACAGGCGCAACTGATCCTTAAACAGCAGGTGCCGATCACGCCGATCGCCAACTCCACGGTGTTCCA
GCCGCTGCGCAAGGAAGTCACTGACTTCAAGATCAGCCCGTTCGGTCTAACCCCCTTCTATGGCGTGGGTATAAATAAGT
AA

Upstream 100 bases:

>100_bases
CCGAGATAGACACCTCACCTAGAAAAACGATATTTCCGCGCCCACCGAAACCCCGGCTACCCTCCTCCCCACAACTACCT
CCAATACGCCCGGGGACTCC

Downstream 100 bases:

>100_bases
CACCCGGCCCCAATCCGGCGCGCACAACGTGACCAGCGCACCGTTTTGGGGCTTCGTTTGCACCGTAAAAACCGGCCGCA
AACGGTCAAATGCGTCAGAA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MDRFTLKPLLITLTLTAITPIANAATTLVYCSEASPAGFDPSQYTSGTDFDASAETVFNRLTQFKRGGTEVEPGLATKWD
VSPDGLQYTFHLRQNVKFHTTDYFTPTRTFNADDVLFTFQRLLDPENAFRKAYPAESPYFTDMGLNTTIKSVEKLDDNTV
RFNLNNVDAAFVQNLAMSFASVQSAEYAAQLLKEGHAADLNQKPVGTGPFVFKRYQKDAQIRYAANKDYWKPEDVKLDNL
VFSITPDAAVRLQKLKTGECQVSGYPRPADIEVMEKDPNLRVLKQPGFNLGFLAYNTTHPPLDQLKVRQALDMAIDKPAI
IKAVYQSAGQLAQNALPPAQWSFDPNIKDAPHDPVKAKALLKEARVAPGTTINLWAMTVQRASNPNARMSAQMIQQDWEK
IGIKANIVSYEWGEYIKRAKNGEHDAMIYGWTGDNGDPDNWLGVLYSCAAVKGSNYAKWCDPAYDKLVQQAKVSTDKSQR
VKLYQQAQLILKQQVPITPIANSTVFQPLRKEVTDFKISPFGLTPFYGVGINK

Sequences:

>Translated_533_residues
MDRFTLKPLLITLTLTAITPIANAATTLVYCSEASPAGFDPSQYTSGTDFDASAETVFNRLTQFKRGGTEVEPGLATKWD
VSPDGLQYTFHLRQNVKFHTTDYFTPTRTFNADDVLFTFQRLLDPENAFRKAYPAESPYFTDMGLNTTIKSVEKLDDNTV
RFNLNNVDAAFVQNLAMSFASVQSAEYAAQLLKEGHAADLNQKPVGTGPFVFKRYQKDAQIRYAANKDYWKPEDVKLDNL
VFSITPDAAVRLQKLKTGECQVSGYPRPADIEVMEKDPNLRVLKQPGFNLGFLAYNTTHPPLDQLKVRQALDMAIDKPAI
IKAVYQSAGQLAQNALPPAQWSFDPNIKDAPHDPVKAKALLKEARVAPGTTINLWAMTVQRASNPNARMSAQMIQQDWEK
IGIKANIVSYEWGEYIKRAKNGEHDAMIYGWTGDNGDPDNWLGVLYSCAAVKGSNYAKWCDPAYDKLVQQAKVSTDKSQR
VKLYQQAQLILKQQVPITPIANSTVFQPLRKEVTDFKISPFGLTPFYGVGINK
>Mature_533_residues
MDRFTLKPLLITLTLTAITPIANAATTLVYCSEASPAGFDPSQYTSGTDFDASAETVFNRLTQFKRGGTEVEPGLATKWD
VSPDGLQYTFHLRQNVKFHTTDYFTPTRTFNADDVLFTFQRLLDPENAFRKAYPAESPYFTDMGLNTTIKSVEKLDDNTV
RFNLNNVDAAFVQNLAMSFASVQSAEYAAQLLKEGHAADLNQKPVGTGPFVFKRYQKDAQIRYAANKDYWKPEDVKLDNL
VFSITPDAAVRLQKLKTGECQVSGYPRPADIEVMEKDPNLRVLKQPGFNLGFLAYNTTHPPLDQLKVRQALDMAIDKPAI
IKAVYQSAGQLAQNALPPAQWSFDPNIKDAPHDPVKAKALLKEARVAPGTTINLWAMTVQRASNPNARMSAQMIQQDWEK
IGIKANIVSYEWGEYIKRAKNGEHDAMIYGWTGDNGDPDNWLGVLYSCAAVKGSNYAKWCDPAYDKLVQQAKVSTDKSQR
VKLYQQAQLILKQQVPITPIANSTVFQPLRKEVTDFKISPFGLTPFYGVGINK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=536, Percent_Identity=52.2388059701493, Blast_Score=569, Evalue=1e-163,
Organism=Escherichia coli, GI1787551, Length=505, Percent_Identity=37.2277227722772, Blast_Score=348, Evalue=3e-97,
Organism=Escherichia coli, GI1787052, Length=455, Percent_Identity=29.010989010989, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787762, Length=542, Percent_Identity=27.1217712177122, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081878, Length=506, Percent_Identity=25.296442687747, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789397, Length=511, Percent_Identity=23.4833659491194, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789887, Length=500, Percent_Identity=23.8, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1787495, Length=463, Percent_Identity=22.8941684665227, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59539; Mature: 59539

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFTLKPLLITLTLTAITPIANAATTLVYCSEASPAGFDPSQYTSGTDFDASAETVFNR
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHH
LTQFKRGGTEVEPGLATKWDVSPDGLQYTFHLRQNVKFHTTDYFTPTRTFNADDVLFTFQ
HHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHH
RLLDPENAFRKAYPAESPYFTDMGLNTTIKSVEKLDDNTVRFNLNNVDAAFVQNLAMSFA
HHHCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHH
SVQSAEYAAQLLKEGHAADLNQKPVGTGPFVFKRYQKDAQIRYAANKDYWKPEDVKLDNL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEECCE
VFSITPDAAVRLQKLKTGECQVSGYPRPADIEVMEKDPNLRVLKQPGFNLGFLAYNTTHP
EEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCC
PLDQLKVRQALDMAIDKPAIIKAVYQSAGQLAQNALPPAQWSFDPNIKDAPHDPVKAKAL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
LKEARVAPGTTINLWAMTVQRASNPNARMSAQMIQQDWEKIGIKANIVSYEWGEYIKRAK
HHHHHCCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHC
NGEHDAMIYGWTGDNGDPDNWLGVLYSCAAVKGSNYAKWCDPAYDKLVQQAKVSTDKSQR
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
VKLYQQAQLILKQQVPITPIANSTVFQPLRKEVTDFKISPFGLTPFYGVGINK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRFTLKPLLITLTLTAITPIANAATTLVYCSEASPAGFDPSQYTSGTDFDASAETVFNR
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHH
LTQFKRGGTEVEPGLATKWDVSPDGLQYTFHLRQNVKFHTTDYFTPTRTFNADDVLFTFQ
HHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCHHHHHHH
RLLDPENAFRKAYPAESPYFTDMGLNTTIKSVEKLDDNTVRFNLNNVDAAFVQNLAMSFA
HHHCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHH
SVQSAEYAAQLLKEGHAADLNQKPVGTGPFVFKRYQKDAQIRYAANKDYWKPEDVKLDNL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEECCE
VFSITPDAAVRLQKLKTGECQVSGYPRPADIEVMEKDPNLRVLKQPGFNLGFLAYNTTHP
EEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCC
PLDQLKVRQALDMAIDKPAIIKAVYQSAGQLAQNALPPAQWSFDPNIKDAPHDPVKAKAL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
LKEARVAPGTTINLWAMTVQRASNPNARMSAQMIQQDWEKIGIKANIVSYEWGEYIKRAK
HHHHHCCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHC
NGEHDAMIYGWTGDNGDPDNWLGVLYSCAAVKGSNYAKWCDPAYDKLVQQAKVSTDKSQR
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
VKLYQQAQLILKQQVPITPIANSTVFQPLRKEVTDFKISPFGLTPFYGVGINK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]