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The map label for this gene is dppB [H]

Identifier: 77457039

GI number: 77457039

Start: 956902

End: 957912

Strand: Reverse

Name: dppB [H]

Synonym: Pfl01_0812

Alternate gene names: 77457039

Gene position: 957912-956902 (Counterclockwise)

Preceding gene: 77457040

Following gene: 77457038

Centisome position: 14.88

GC content: 62.22

Gene sequence:

>1011_bases
ATGTTTAGTTTTATTGCCCGCCGACTGGGGTTATTGATCCCCACGTTTTTCGGCATCACCTTGCTGACTTTCGCGTTGAT
TCGCATGATTCCCGGCGACCCCGTGGAAGTGATGATGGGCGAACGTCGGGTCGACCCCGAAATGCACGCTCAGGCAATGG
AACGCCTCGGTCTGAACAAACCGCTGTACGCCCAGTACCTGGACTACATCGGCAAACTGGCCCACGGCGACCTCGGCGAA
TCCCTGCGCACCCGTGAGAGCGTATGGACCGAGTTCACCTCCCTCTTCCCGGCGACCCTGGAACTGTCCATGGCCGCCCT
GCTGTTCGCTGGCATCCTGGGCCTGCTGGCCGGGGTGATCGCGGCCCTCAAGCGAGGATCCCTGTTCGACCACGGGGTGA
TGGGCATCTCCCTTGCGGGTTATTCGATGCCGATCTTCTGGTGGGGCCTGATCCTCATCATGTTCTTCTCGGTGAGCCTG
GGCTGGACCCCGGTGTCCGGGCGGATCGACCTGCTTTACGACATCGAGCCGCGCACCGGTTTCATGCTGATCGACACCCT
GCTGGCCGATGACATGGGCGCGTTCCTCGATGCCCTGCACCACCTGATCCTGCCGGCCATCGTGCTGGGCACCATTCCGC
TGGCGGTGATCGCGCGGATGACCCGTTCGTCGATGCTCGAAGTGCTGCGTGAGGACTACATCCGTACCGCCAAGGCCAAA
GGCCTGTCGCCGTCGCGCGTGGTGTTCGTGCACGGCCTGCGCAACGCGCTGATCCCGGTGCTGACCGTGGTCGGCCTGCA
AGTCGGCACCCTGCTGGCCGGTGCGGTCCTGACCGAAACCATCTTCTCCTGGCCCGGCATCGGTAAATGGCTGATCGAAG
CCATCGGCGCCCGGGACTACCCGGTTGTGCAAAACGGCATCCTGTTAATCGCCTGCCTGGTGATTCTGGTCAACTTCGTG
GTGGATATCCTCTACGGCTTTGCCAACCCACGCATCCGTCATCAGCGCTGA

Upstream 100 bases:

>100_bases
AACTTCGCCACCACCCAGGTGAAGTAGATAAGAAACTCCCGGCGCCCCTGACCCCAGGGGCGCCGGGCACGCCTAACCGG
CTGATGAGGTACCACACACG

Downstream 100 bases:

>100_bases
GGTCAATACCCATGAGCACTCCAACTTCCTCAGTAGCCACCGCTGCCACCGCCGTGGATCAAAGTCTGCTGTACCCGTCT
CCGTACAAAGAGTTCTGGCA

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MFSFIARRLGLLIPTFFGITLLTFALIRMIPGDPVEVMMGERRVDPEMHAQAMERLGLNKPLYAQYLDYIGKLAHGDLGE
SLRTRESVWTEFTSLFPATLELSMAALLFAGILGLLAGVIAALKRGSLFDHGVMGISLAGYSMPIFWWGLILIMFFSVSL
GWTPVSGRIDLLYDIEPRTGFMLIDTLLADDMGAFLDALHHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTAKAK
GLSPSRVVFVHGLRNALIPVLTVVGLQVGTLLAGAVLTETIFSWPGIGKWLIEAIGARDYPVVQNGILLIACLVILVNFV
VDILYGFANPRIRHQR

Sequences:

>Translated_336_residues
MFSFIARRLGLLIPTFFGITLLTFALIRMIPGDPVEVMMGERRVDPEMHAQAMERLGLNKPLYAQYLDYIGKLAHGDLGE
SLRTRESVWTEFTSLFPATLELSMAALLFAGILGLLAGVIAALKRGSLFDHGVMGISLAGYSMPIFWWGLILIMFFSVSL
GWTPVSGRIDLLYDIEPRTGFMLIDTLLADDMGAFLDALHHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTAKAK
GLSPSRVVFVHGLRNALIPVLTVVGLQVGTLLAGAVLTETIFSWPGIGKWLIEAIGARDYPVVQNGILLIACLVILVNFV
VDILYGFANPRIRHQR
>Mature_336_residues
MFSFIARRLGLLIPTFFGITLLTFALIRMIPGDPVEVMMGERRVDPEMHAQAMERLGLNKPLYAQYLDYIGKLAHGDLGE
SLRTRESVWTEFTSLFPATLELSMAALLFAGILGLLAGVIAALKRGSLFDHGVMGISLAGYSMPIFWWGLILIMFFSVSL
GWTPVSGRIDLLYDIEPRTGFMLIDTLLADDMGAFLDALHHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTAKAK
GLSPSRVVFVHGLRNALIPVLTVVGLQVGTLLAGAVLTETIFSWPGIGKWLIEAIGARDYPVVQNGILLIACLVILVNFV
VDILYGFANPRIRHQR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=64.306784660767, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1787053, Length=339, Percent_Identity=41.8879056047198, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=43.6746987951807, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1787550, Length=278, Percent_Identity=40.6474820143885, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=37.3134328358209, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789888, Length=338, Percent_Identity=34.0236686390533, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1788504, Length=377, Percent_Identity=26.2599469496021, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37020; Mature: 37020

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFIARRLGLLIPTFFGITLLTFALIRMIPGDPVEVMMGERRVDPEMHAQAMERLGLNK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
PLYAQYLDYIGKLAHGDLGESLRTRESVWTEFTSLFPATLELSMAALLFAGILGLLAGVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALKRGSLFDHGVMGISLAGYSMPIFWWGLILIMFFSVSLGWTPVSGRIDLLYDIEPRTG
HHHHCCCCHHCCCHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
FMLIDTLLADDMGAFLDALHHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTAKAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPSRVVFVHGLRNALIPVLTVVGLQVGTLLAGAVLTETIFSWPGIGKWLIEAIGARDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PVVQNGILLIACLVILVNFVVDILYGFANPRIRHQR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFSFIARRLGLLIPTFFGITLLTFALIRMIPGDPVEVMMGERRVDPEMHAQAMERLGLNK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
PLYAQYLDYIGKLAHGDLGESLRTRESVWTEFTSLFPATLELSMAALLFAGILGLLAGVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALKRGSLFDHGVMGISLAGYSMPIFWWGLILIMFFSVSLGWTPVSGRIDLLYDIEPRTG
HHHHCCCCHHCCCHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
FMLIDTLLADDMGAFLDALHHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTAKAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPSRVVFVHGLRNALIPVLTVVGLQVGTLLAGAVLTETIFSWPGIGKWLIEAIGARDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PVVQNGILLIACLVILVNFVVDILYGFANPRIRHQR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]