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The map label for this gene is dppA [H]

Identifier: 77457040

GI number: 77457040

Start: 957986

End: 959581

Strand: Reverse

Name: dppA [H]

Synonym: Pfl01_0813

Alternate gene names: 77457040

Gene position: 959581-957986 (Counterclockwise)

Preceding gene: 77457041

Following gene: 77457039

Centisome position: 14.9

GC content: 60.34

Gene sequence:

>1596_bases
ATGAAAATGCTTCCCCTACGTGCGGCCATCGCGGCTGCGTTGCTGAGTGTCGCTGTCGGCGTCTCGGCCAAACCCTTGGT
GGTCTGCACCGAAGCCAGTCCGGAAGGCTTCGATATGGTCCAGTACACGACTGCAGTCACTGCCGACGCGGTGGCCGAAA
CCATCTTCAACCGTCTGGCGGACTTCAAGCCCGGCACCACCGAAGTGATTCCGGCGCTGGCCGAGTCCTGGGACATCAGC
GAAGACGGCCTGACCTACACGTTCCATCTGCGCAAAGGCGTCAAGTTTCACACCACCGAATATTTCAAGCCGACCCGCGA
CATGAACGCCGACGACGTGGTCTGGAGTTTCCAGCGTCAGCTGGACCCGAATCACCCGTGGCACAAGCTGTCGAGCGTGG
GCTTCCCGTACTTTGAAAGCATGGGCTTCAAGGAACTGCTCAAAAGCGTCGAGAAAGTCGACGACAACACCGTCAAGTTC
ACCCTGACCCGCCGCGAAGCGCCGTTCCTGGCCGACATCGCCATGGCGTTCTCCTCGATCTATCCGGCCGAATACGCCGA
CCAGTTGCTCAAGGCCAACAAGACTGGCGACCTGAACAACAAACCGGTCGGCACCGGCCCGTTCATCTTCCAGCGTTACG
CCAAGGACGCCCAGGTTCGCTTCAAGGCCAACCCGGACTACTTCCGCGGCAAGGCCCCGGCTGACGCGCTGATCCTGGCG
ATTGCCACCGACAACAACGTGCGTCTGCAGAAACTCAAGGCCAACGAGTGCCAGATCGCGCTGTACCCGAAACCGGATGA
CATCCCGAGCATCAAGAAAGACAGCAACCTGAAAGTCGACGAACTGGATGCGATGACCGTCTCCTACGTCGCCATGAACA
CCCAGCACAAGTACATCAGCGACGTGCGGGTGCGCAAAGCGATCGACATCGCCTTCGACAAGGAAGCCTACGTCAACGCC
CTGTTCGGCAAAGGCAACGCCAGCGTGGCGGTCAACCCGTACCCGCCGACCCTGCTGGGCTACAACCACGAGCTGAAAAA
CCCGCCACGTGACCTCGACAAGGCCCGCGCCCTGCTCAAGGAAGCCGGCGTACCGGAAGGCACCACGTTCACCCTGTTCA
CCCGCAACGGTGGCGGCCCGACCAACCCGAACCCGATGCTCGGCGCGCAGATGATGCAGGCTGACCTGGCGAAAGTCGGG
ATCAAGATCGACATCCGCGTGATGGAATGGGGCGAGATGCTCAAACGCGCCAAGGCCGGCGAGCACGACATGGTCTCGGC
CGGATGGGCGGGCGACAACGGCGACCCGGATAACTTCCTGACGCCTATGCTCAGTTGCGAAGCCGCCAAGAACGGCGAAA
ACTACGCGCGCTGGTGCAACGAGAAATTCCAGGCCCTGCTCGACGAAGCACGGGCTAAAGTAGATCCGGCCGAACGCGCC
AAACTGTATGAAGAAGCCCAGGTGATCTTCAATCAGGACCAACCGTGGATCAGCATGGCCCACACCCGCATGTTCACCGC
AATGCGCAACAACGTAGAGGGTTATCACATCAGCCCTCTGACAACCAATAACTTCGCCACCACCCAGGTGAAGTAG

Upstream 100 bases:

>100_bases
CGTTCCGTTCAACATCCTGTAAAAACGCCAGCCGACGGCTGACTCAGTGACGAGTCGGCCGTTCGGCTTTTTGTCTTCAA
CCGATTGCAGAGGGTTCTTG

Downstream 100 bases:

>100_bases
ATAAGAAACTCCCGGCGCCCCTGACCCCAGGGGCGCCGGGCACGCCTAACCGGCTGATGAGGTACCACACACGATGTTTA
GTTTTATTGCCCGCCGACTG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MKMLPLRAAIAAALLSVAVGVSAKPLVVCTEASPEGFDMVQYTTAVTADAVAETIFNRLADFKPGTTEVIPALAESWDIS
EDGLTYTFHLRKGVKFHTTEYFKPTRDMNADDVVWSFQRQLDPNHPWHKLSSVGFPYFESMGFKELLKSVEKVDDNTVKF
TLTRREAPFLADIAMAFSSIYPAEYADQLLKANKTGDLNNKPVGTGPFIFQRYAKDAQVRFKANPDYFRGKAPADALILA
IATDNNVRLQKLKANECQIALYPKPDDIPSIKKDSNLKVDELDAMTVSYVAMNTQHKYISDVRVRKAIDIAFDKEAYVNA
LFGKGNASVAVNPYPPTLLGYNHELKNPPRDLDKARALLKEAGVPEGTTFTLFTRNGGGPTNPNPMLGAQMMQADLAKVG
IKIDIRVMEWGEMLKRAKAGEHDMVSAGWAGDNGDPDNFLTPMLSCEAAKNGENYARWCNEKFQALLDEARAKVDPAERA
KLYEEAQVIFNQDQPWISMAHTRMFTAMRNNVEGYHISPLTTNNFATTQVK

Sequences:

>Translated_531_residues
MKMLPLRAAIAAALLSVAVGVSAKPLVVCTEASPEGFDMVQYTTAVTADAVAETIFNRLADFKPGTTEVIPALAESWDIS
EDGLTYTFHLRKGVKFHTTEYFKPTRDMNADDVVWSFQRQLDPNHPWHKLSSVGFPYFESMGFKELLKSVEKVDDNTVKF
TLTRREAPFLADIAMAFSSIYPAEYADQLLKANKTGDLNNKPVGTGPFIFQRYAKDAQVRFKANPDYFRGKAPADALILA
IATDNNVRLQKLKANECQIALYPKPDDIPSIKKDSNLKVDELDAMTVSYVAMNTQHKYISDVRVRKAIDIAFDKEAYVNA
LFGKGNASVAVNPYPPTLLGYNHELKNPPRDLDKARALLKEAGVPEGTTFTLFTRNGGGPTNPNPMLGAQMMQADLAKVG
IKIDIRVMEWGEMLKRAKAGEHDMVSAGWAGDNGDPDNFLTPMLSCEAAKNGENYARWCNEKFQALLDEARAKVDPAERA
KLYEEAQVIFNQDQPWISMAHTRMFTAMRNNVEGYHISPLTTNNFATTQVK
>Mature_531_residues
MKMLPLRAAIAAALLSVAVGVSAKPLVVCTEASPEGFDMVQYTTAVTADAVAETIFNRLADFKPGTTEVIPALAESWDIS
EDGLTYTFHLRKGVKFHTTEYFKPTRDMNADDVVWSFQRQLDPNHPWHKLSSVGFPYFESMGFKELLKSVEKVDDNTVKF
TLTRREAPFLADIAMAFSSIYPAEYADQLLKANKTGDLNNKPVGTGPFIFQRYAKDAQVRFKANPDYFRGKAPADALILA
IATDNNVRLQKLKANECQIALYPKPDDIPSIKKDSNLKVDELDAMTVSYVAMNTQHKYISDVRVRKAIDIAFDKEAYVNA
LFGKGNASVAVNPYPPTLLGYNHELKNPPRDLDKARALLKEAGVPEGTTFTLFTRNGGGPTNPNPMLGAQMMQADLAKVG
IKIDIRVMEWGEMLKRAKAGEHDMVSAGWAGDNGDPDNFLTPMLSCEAAKNGENYARWCNEKFQALLDEARAKVDPAERA
KLYEEAQVIFNQDQPWISMAHTRMFTAMRNNVEGYHISPLTTNNFATTQVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=526, Percent_Identity=46.958174904943, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1787551, Length=501, Percent_Identity=34.3313373253493, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1787052, Length=527, Percent_Identity=29.2220113851992, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787762, Length=509, Percent_Identity=26.1296660117878, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789397, Length=491, Percent_Identity=24.6435845213849, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787495, Length=449, Percent_Identity=24.4988864142539, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789887, Length=477, Percent_Identity=23.8993710691824, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87081878, Length=452, Percent_Identity=21.4601769911504, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59059; Mature: 59059

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMLPLRAAIAAALLSVAVGVSAKPLVVCTEASPEGFDMVQYTTAVTADAVAETIFNRLA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFKPGTTEVIPALAESWDISEDGLTYTFHLRKGVKFHTTEYFKPTRDMNADDVVWSFQRQ
CCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEHHCCCCCCCCCHHHHHHHHHHH
LDPNHPWHKLSSVGFPYFESMGFKELLKSVEKVDDNTVKFTLTRREAPFLADIAMAFSSI
CCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHC
YPAEYADQLLKANKTGDLNNKPVGTGPFIFQRYAKDAQVRFKANPDYFRGKAPADALILA
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEE
IATDNNVRLQKLKANECQIALYPKPDDIPSIKKDSNLKVDELDAMTVSYVAMNTQHKYIS
EEECCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHCCEEEEEEEECCCHHHHH
DVRVRKAIDIAFDKEAYVNALFGKGNASVAVNPYPPTLLGYNHELKNPPRDLDKARALLK
HHHHHHHHHEEECCHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EAGVPEGTTFTLFTRNGGGPTNPNPMLGAQMMQADLAKVGIKIDIRVMEWGEMLKRAKAG
HCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHCCC
EHDMVSAGWAGDNGDPDNFLTPMLSCEAAKNGENYARWCNEKFQALLDEARAKVDPAERA
CCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
KLYEEAQVIFNQDQPWISMAHTRMFTAMRNNVEGYHISPLTTNNFATTQVK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEECCCEEEEECC
>Mature Secondary Structure
MKMLPLRAAIAAALLSVAVGVSAKPLVVCTEASPEGFDMVQYTTAVTADAVAETIFNRLA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFKPGTTEVIPALAESWDISEDGLTYTFHLRKGVKFHTTEYFKPTRDMNADDVVWSFQRQ
CCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEHHCCCCCCCCCHHHHHHHHHHH
LDPNHPWHKLSSVGFPYFESMGFKELLKSVEKVDDNTVKFTLTRREAPFLADIAMAFSSI
CCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHC
YPAEYADQLLKANKTGDLNNKPVGTGPFIFQRYAKDAQVRFKANPDYFRGKAPADALILA
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEE
IATDNNVRLQKLKANECQIALYPKPDDIPSIKKDSNLKVDELDAMTVSYVAMNTQHKYIS
EEECCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHCCEEEEEEEECCCHHHHH
DVRVRKAIDIAFDKEAYVNALFGKGNASVAVNPYPPTLLGYNHELKNPPRDLDKARALLK
HHHHHHHHHEEECCHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EAGVPEGTTFTLFTRNGGGPTNPNPMLGAQMMQADLAKVGIKIDIRVMEWGEMLKRAKAG
HCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHCCC
EHDMVSAGWAGDNGDPDNFLTPMLSCEAAKNGENYARWCNEKFQALLDEARAKVDPAERA
CCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
KLYEEAQVIFNQDQPWISMAHTRMFTAMRNNVEGYHISPLTTNNFATTQVK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]