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The map label for this gene is csgA [H]

Identifier: 77456904

GI number: 77456904

Start: 791376

End: 792071

Strand: Reverse

Name: csgA [H]

Synonym: Pfl01_0676

Alternate gene names: 77456904

Gene position: 792071-791376 (Counterclockwise)

Preceding gene: 77456905

Following gene: 77456903

Centisome position: 12.3

GC content: 62.21

Gene sequence:

>696_bases
ATGTCCGCACTGAATCCTGCCAAGCACGCACTGATCATCGGCGCCTCCCGGGGCCTGGGCCTGGGTCTGGTGAAAACCCT
GCTGGCCGACGGCTGGCAAGTCACCGCCACGGTTCGCAATCCTTCCAATGCCGAGGCTCTCGAAGCACTGGGCAACGTGC
AAATCGAAAAACTCGACATGGACGACCAGCAAGCGGTGATCGCCCTGAGCCAGAAGCTCAAGGGCGAGACCTTTGACCTG
CTGTTCGTCAACGCCGGGGTCAAAGGCCCCGAAGTGCAGACCCCGGGCGGCGCGACGCTGGCGGAAGTCGGTCAGTTGTT
CTTCACCAACGCGGTGGCACCGATCAATCTGGCCCAGCGCTTTGTCGGGCAGATCCGCGACGGCAGCGGCGTGCTGGCGT
TCATGAGTTCGGTGCTCGGCAGCGTGACCATGCCCGACGCGCCGGAACTCGCGCTGTACAAGGCGAGCAAAGCGGCGCTG
AACTCGATGACCAACAGCTTCGTCACTCAATTGGGCGAGCAGAAACTCACCGTGCTATCGCTGCATCCGGGCTGGGTGAA
AACCGACATGGGCGGCGAAGGTGCCGACATCGACGTTGAGACCAGCACCCGTGGCCTGGTGGATCAGGTGGATGCGTTCG
CCGGCAAGGGGGGCCATCATTTCGTGAACTACAAGGGTGAAACCATTCCCTGGTAA

Upstream 100 bases:

>100_bases
CATGGCCGAACTCGGTGAGTTGCGCCAGGAATTGCAGCATCGGCTCGGTCAACGTTGTCCATTGAACCCGTGATCTTTCA
ACTTTCAAGGAAAGCCAATC

Downstream 100 bases:

>100_bases
TCACTGAACCCTGTGGGGGGCTTGCCCCCGCAGGGTTATGCCGGTGTCTGGTCGGGTTGGGCTTGCCCGTCGCAACATTT
TGTTCGAAACTCCGCACCTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSALNPAKHALIIGASRGLGLGLVKTLLADGWQVTATVRNPSNAEALEALGNVQIEKLDMDDQQAVIALSQKLKGETFDL
LFVNAGVKGPEVQTPGGATLAEVGQLFFTNAVAPINLAQRFVGQIRDGSGVLAFMSSVLGSVTMPDAPELALYKASKAAL
NSMTNSFVTQLGEQKLTVLSLHPGWVKTDMGGEGADIDVETSTRGLVDQVDAFAGKGGHHFVNYKGETIPW

Sequences:

>Translated_231_residues
MSALNPAKHALIIGASRGLGLGLVKTLLADGWQVTATVRNPSNAEALEALGNVQIEKLDMDDQQAVIALSQKLKGETFDL
LFVNAGVKGPEVQTPGGATLAEVGQLFFTNAVAPINLAQRFVGQIRDGSGVLAFMSSVLGSVTMPDAPELALYKASKAAL
NSMTNSFVTQLGEQKLTVLSLHPGWVKTDMGGEGADIDVETSTRGLVDQVDAFAGKGGHHFVNYKGETIPW
>Mature_230_residues
SALNPAKHALIIGASRGLGLGLVKTLLADGWQVTATVRNPSNAEALEALGNVQIEKLDMDDQQAVIALSQKLKGETFDLL
FVNAGVKGPEVQTPGGATLAEVGQLFFTNAVAPINLAQRFVGQIRDGSGVLAFMSSVLGSVTMPDAPELALYKASKAALN
SMTNSFVTQLGEQKLTVLSLHPGWVKTDMGGEGADIDVETSTRGLVDQVDAFAGKGGHHFVNYKGETIPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI2367365, Length=188, Percent_Identity=29.7872340425532, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17532177, Length=225, Percent_Identity=34.2222222222222, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559962, Length=248, Percent_Identity=30.241935483871, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559964, Length=248, Percent_Identity=32.6612903225806, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI72001658, Length=245, Percent_Identity=29.3877551020408, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17558990, Length=223, Percent_Identity=31.390134529148, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558994, Length=238, Percent_Identity=28.9915966386555, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193207563, Length=240, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558992, Length=236, Percent_Identity=28.3898305084746, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17541382, Length=260, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17542178, Length=234, Percent_Identity=28.6324786324786, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322779, Length=247, Percent_Identity=29.1497975708502, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=197, Percent_Identity=28.9340101522843, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24640547, Length=244, Percent_Identity=35.655737704918, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=32.4468085106383, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24259; Mature: 24128

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNPAKHALIIGASRGLGLGLVKTLLADGWQVTATVRNPSNAEALEALGNVQIEKLDM
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCCCEEEEECC
DDQQAVIALSQKLKGETFDLLFVNAGVKGPEVQTPGGATLAEVGQLFFTNAVAPINLAQR
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
FVGQIRDGSGVLAFMSSVLGSVTMPDAPELALYKASKAALNSMTNSFVTQLGEQKLTVLS
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LHPGWVKTDMGGEGADIDVETSTRGLVDQVDAFAGKGGHHFVNYKGETIPW
ECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SALNPAKHALIIGASRGLGLGLVKTLLADGWQVTATVRNPSNAEALEALGNVQIEKLDM
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCCCEEEEECC
DDQQAVIALSQKLKGETFDLLFVNAGVKGPEVQTPGGATLAEVGQLFFTNAVAPINLAQR
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
FVGQIRDGSGVLAFMSSVLGSVTMPDAPELALYKASKAALNSMTNSFVTQLGEQKLTVLS
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LHPGWVKTDMGGEGADIDVETSTRGLVDQVDAFAGKGGHHFVNYKGETIPW
ECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]