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The map label for this gene is merR1 [H]

Identifier: 77456905

GI number: 77456905

Start: 792099

End: 792449

Strand: Reverse

Name: merR1 [H]

Synonym: Pfl01_0677

Alternate gene names: 77456905

Gene position: 792449-792099 (Counterclockwise)

Preceding gene: 77456907

Following gene: 77456904

Centisome position: 12.31

GC content: 59.83

Gene sequence:

>351_bases
ATGCGCATCGGTGAGTTGGCTCAGGCCTGCGATGTCAGCCGTGACACGCTGCGTTTTTACGAGGAGCGCGGATTGATCGC
GGCGCAACGCAGCGCCAACGGTTATCGCGACTATCCGCCGGAGATGGTGCAACTGGTGCTGTACATCAAGACGGCGCAAC
GTCTGGGCTTTACCCTTGGCGAGATCGGCAACAGCGTTGGCGCGTTGTGGCACTCGCCAAACCCCGACACCACCGTCACG
CAACTGCTGCAAGACAAACTCAAGCTGGTCGAAACCCGCATGGCCGAACTCGGTGAGTTGCGCCAGGAATTGCAGCATCG
GCTCGGTCAACGTTGTCCATTGAACCCGTGA

Upstream 100 bases:

>100_bases
TGCGTTGAAGTCCACATCATCCTTGCTCCAAAAATTCAGGGAGCAACCACGGTAAAGCCTGGAGTATGCTCCAGGGTCAA
ACACTTTCGAGACCTGCAAG

Downstream 100 bases:

>100_bases
TCTTTCAACTTTCAAGGAAAGCCAATCATGTCCGCACTGAATCCTGCCAAGCACGCACTGATCATCGGCGCCTCCCGGGG
CCTGGGCCTGGGTCTGGTGA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MRIGELAQACDVSRDTLRFYEERGLIAAQRSANGYRDYPPEMVQLVLYIKTAQRLGFTLGEIGNSVGALWHSPNPDTTVT
QLLQDKLKLVETRMAELGELRQELQHRLGQRCPLNP

Sequences:

>Translated_116_residues
MRIGELAQACDVSRDTLRFYEERGLIAAQRSANGYRDYPPEMVQLVLYIKTAQRLGFTLGEIGNSVGALWHSPNPDTTVT
QLLQDKLKLVETRMAELGELRQELQHRLGQRCPLNP
>Mature_116_residues
MRIGELAQACDVSRDTLRFYEERGLIAAQRSANGYRDYPPEMVQLVLYIKTAQRLGFTLGEIGNSVGALWHSPNPDTTVT
QLLQDKLKLVETRMAELGELRQELQHRLGQRCPLNP

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=116, Percent_Identity=34.4827586206897, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 13167; Mature: 13167

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGELAQACDVSRDTLRFYEERGLIAAQRSANGYRDYPPEMVQLVLYIKTAQRLGFTLG
CCHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EIGNSVGALWHSPNPDTTVTQLLQDKLKLVETRMAELGELRQELQHRLGQRCPLNP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRIGELAQACDVSRDTLRFYEERGLIAAQRSANGYRDYPPEMVQLVLYIKTAQRLGFTLG
CCHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EIGNSVGALWHSPNPDTTVTQLLQDKLKLVETRMAELGELRQELQHRLGQRCPLNP
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536669; 10559175; 2492496; 2305262 [H]