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The map label for this gene is cobL [H]

Identifier: 77456831

GI number: 77456831

Start: 695324

End: 696535

Strand: Reverse

Name: cobL [H]

Synonym: Pfl01_0603

Alternate gene names: 77456831

Gene position: 696535-695324 (Counterclockwise)

Preceding gene: 77456838

Following gene: 77456830

Centisome position: 10.82

GC content: 67.74

Gene sequence:

>1212_bases
ATGTCACCCTGGCTGACAGTAGTAGGAATCGGTGAAGACGGCTTCAAAGGCCTGGGCAAGAATGCCCGGCGCGCCTTGAT
GGACGCTTCGCGGATCATCGGCGGTCAGCGTCAGCTGGATCTGTTGCCGGTGTGCATCCGTGGCGAGCGCCAGTTGTGGC
CGAGCCCGTTTTCCCTGGCCCCGGTGCTCGAGCGTCGCGGTGAAGCCGTGTGTGTGCTGGCCAGTGGTGATCCGATGTTC
TACGGCGTTGGCGCGAGTCTGGCGCGTCAGGTTCCGGAGGCCGAGATGCTGGTCCTGCCGGCCCCGTCGTCCTGCTCGCT
GGCGGCGGCCCGACTGGGCTGGCCGTTGCAGGACGTCAGCGTGCTGTCGCTGGTGGCTCGCCCGCTGGCGGCTCTCAATG
CACAACTGTTTGGCGGCGTGCGCCTGTTGCTGCTGAGCAATGACGGCCAGAGCCCGGCGGCGGTTGCCACGTTGCTGCGT
GAACGCGGATTCGGCGCCAGTCGCCTGAGCGTGCTGGAACATCTGGGCGGCAGCGCCGAACGCCGGATCGACGGCAGCGC
CAACGACTGGAACGATCCGCTCATTGCCGACCTCAACGTGATCGCCCTCGAGTGCCTCGCCGATCCGCAGACACCGCGCC
TGTCGCGCCTCGCCGGCCTGCCGGACTCGGCCTTCCGGCACGACGGCCAACTGACCAAGCGCGACGTGCGCGCGATCACC
CTCGCCCGCCTCGCCCCGACACCGGGCGAATTGCTCTGGGACGTCGGCGCGGGCAGCGGCTCGATCGGCATCGAGTGGAT
GCGCGCGCACCCGAGCTGTCGCGCACTGGCCATCGAGGCTGACGATGGTCGCCAGCAGCTGATCGAACACAACCGCGATG
CGCTGGGTGTGCCCGGCCTGCAACTGATTCGTGGCAGCGCCCCGCAAGCTCTCGCCGGGCTGGAGCGACCGGACGCGATT
TTCATCGGCGGCGGCGTGACCCGCGAAGGCGTGCTGGAAACCTGCTGGGCACAACTCAAACCCGGTGGCCGACTGGTCGC
CAACGCTGTGACCCTGCAAAGCGAAATGACCTTGATGAGCTGGCGCGAACGCCACGGCGGCGAACTGACCCGCATCCACA
TCGCCCAGGCACAGCCGCTGGGCGAATTCGACACCTGGCGCCAGGCGTTGCCGATCACCCTGCTCGATCTGGTCAAACCC
CTCGATGCGTGA

Upstream 100 bases:

>100_bases
CGCGGGCGAAGGCGCGGTATTATGCCTGCTTTGTCCGACGGCATGAAAAGTCTGCCCGTCGGAACGGCGCGTTTGCGGAC
ACTTTTTTGAGGGGCTACAG

Downstream 100 bases:

>100_bases
CGAAACCGCCGAACAACCCGCGCCCCTGCGCAGCGGCCTGACTACCGGCAGCTGCGCCACGGCCACCAGCCTCGCCGCCG
CGCGCCTGTTGCTCGGTGGA

Product: uroporphyrin-III C/tetrapyrrole methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSPWLTVVGIGEDGFKGLGKNARRALMDASRIIGGQRQLDLLPVCIRGERQLWPSPFSLAPVLERRGEAVCVLASGDPMF
YGVGASLARQVPEAEMLVLPAPSSCSLAAARLGWPLQDVSVLSLVARPLAALNAQLFGGVRLLLLSNDGQSPAAVATLLR
ERGFGASRLSVLEHLGGSAERRIDGSANDWNDPLIADLNVIALECLADPQTPRLSRLAGLPDSAFRHDGQLTKRDVRAIT
LARLAPTPGELLWDVGAGSGSIGIEWMRAHPSCRALAIEADDGRQQLIEHNRDALGVPGLQLIRGSAPQALAGLERPDAI
FIGGGVTREGVLETCWAQLKPGGRLVANAVTLQSEMTLMSWRERHGGELTRIHIAQAQPLGEFDTWRQALPITLLDLVKP
LDA

Sequences:

>Translated_403_residues
MSPWLTVVGIGEDGFKGLGKNARRALMDASRIIGGQRQLDLLPVCIRGERQLWPSPFSLAPVLERRGEAVCVLASGDPMF
YGVGASLARQVPEAEMLVLPAPSSCSLAAARLGWPLQDVSVLSLVARPLAALNAQLFGGVRLLLLSNDGQSPAAVATLLR
ERGFGASRLSVLEHLGGSAERRIDGSANDWNDPLIADLNVIALECLADPQTPRLSRLAGLPDSAFRHDGQLTKRDVRAIT
LARLAPTPGELLWDVGAGSGSIGIEWMRAHPSCRALAIEADDGRQQLIEHNRDALGVPGLQLIRGSAPQALAGLERPDAI
FIGGGVTREGVLETCWAQLKPGGRLVANAVTLQSEMTLMSWRERHGGELTRIHIAQAQPLGEFDTWRQALPITLLDLVKP
LDA
>Mature_402_residues
SPWLTVVGIGEDGFKGLGKNARRALMDASRIIGGQRQLDLLPVCIRGERQLWPSPFSLAPVLERRGEAVCVLASGDPMFY
GVGASLARQVPEAEMLVLPAPSSCSLAAARLGWPLQDVSVLSLVARPLAALNAQLFGGVRLLLLSNDGQSPAAVATLLRE
RGFGASRLSVLEHLGGSAERRIDGSANDWNDPLIADLNVIALECLADPQTPRLSRLAGLPDSAFRHDGQLTKRDVRAITL
ARLAPTPGELLWDVGAGSGSIGIEWMRAHPSCRALAIEADDGRQQLIEHNRDALGVPGLQLIRGSAPQALAGLERPDAIF
IGGGVTREGVLETCWAQLKPGGRLVANAVTLQSEMTLMSWRERHGGELTRIHIAQAQPLGEFDTWRQALPITLLDLVKPL
DA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43108; Mature: 42977

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPWLTVVGIGEDGFKGLGKNARRALMDASRIIGGQRQLDLLPVCIRGERQLWPSPFSLA
CCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHH
PVLERRGEAVCVLASGDPMFYGVGASLARQVPEAEMLVLPAPSSCSLAAARLGWPLQDVS
HHHHCCCCEEEEEECCCCEEEECCHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCHHHHH
VLSLVARPLAALNAQLFGGVRLLLLSNDGQSPAAVATLLRERGFGASRLSVLEHLGGSAE
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
RRIDGSANDWNDPLIADLNVIALECLADPQTPRLSRLAGLPDSAFRHDGQLTKRDVRAIT
CCCCCCCCCCCCCEEECHHHEEEEECCCCCCCHHHHHCCCCCHHHHCCCCCCHHHHHHHH
LARLAPTPGELLWDVGAGSGSIGIEWMRAHPSCRALAIEADDGRQQLIEHNRDALGVPGL
HHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCH
QLIRGSAPQALAGLERPDAIFIGGGVTREGVLETCWAQLKPGGRLVANAVTLQSEMTLMS
HHHCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH
WRERHGGELTRIHIAQAQPLGEFDTWRQALPITLLDLVKPLDA
HHHHCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
SPWLTVVGIGEDGFKGLGKNARRALMDASRIIGGQRQLDLLPVCIRGERQLWPSPFSLA
CCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHH
PVLERRGEAVCVLASGDPMFYGVGASLARQVPEAEMLVLPAPSSCSLAAARLGWPLQDVS
HHHHCCCCEEEEEECCCCEEEECCHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCHHHHH
VLSLVARPLAALNAQLFGGVRLLLLSNDGQSPAAVATLLRERGFGASRLSVLEHLGGSAE
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
RRIDGSANDWNDPLIADLNVIALECLADPQTPRLSRLAGLPDSAFRHDGQLTKRDVRAIT
CCCCCCCCCCCCCEEECHHHEEEEECCCCCCCHHHHHCCCCCHHHHCCCCCCHHHHHHHH
LARLAPTPGELLWDVGAGSGSIGIEWMRAHPSCRALAIEADDGRQQLIEHNRDALGVPGL
HHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCH
QLIRGSAPQALAGLERPDAIFIGGGVTREGVLETCWAQLKPGGRLVANAVTLQSEMTLMS
HHHCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHH
WRERHGGELTRIHIAQAQPLGEFDTWRQALPITLLDLVKPLDA
HHHHCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]