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The map label for this gene is aroB [H]

Identifier: 77456639

GI number: 77456639

Start: 467222

End: 468322

Strand: Direct

Name: aroB [H]

Synonym: Pfl01_0411

Alternate gene names: 77456639

Gene position: 467222-468322 (Clockwise)

Preceding gene: 77456638

Following gene: 77456640

Centisome position: 7.26

GC content: 62.22

Gene sequence:

>1101_bases
ATGCAGACACTCAAGGTCGACCTAGGCGAACGCAGCTACCCGATTCACATTGGCGAGGGACTGCTGGACCAGCCAGAGTT
GCTGGCCCCGCATATCCATGGGCGGCAAGTGGCAATCATCTCCAACGAGACCGTTGCGCCGCTCTATCTCGAGCGTCTGA
CCCGCAGCCTGGCGCAGTTCTCGGTGGTTTCCGTGGTGCTGCCCGACGGCGAAGCCTTCAAGAACTGGGAAACCCTGCAA
CTGATCTTCGACGGCCTGCTGACCGCCCGTCATGATCGCCGCACCACAGTGATCGCCCTCGGTGGCGGTGTGATCGGCGA
CATGGCCGGTTTCGCGGCCGCCTGCTACCAGCGCGGCGTCGATTTCATCCAGATCCCTACCACGCTGCTTTCCCAGGTCG
ATTCGTCGGTGGGCGGCAAGACCGGGATCAACCATCCGCTGGGCAAGAACATGGTCGGCGCGTTCTATCAGCCGAACGTG
GTGCTGATCGATACCGCGTCCCTGAAGACCCTGCCAGCGCGTGAGCTCTCGGCTGGCCTGGCGGAGGTCATCAAGTACGG
TCTGATCTGCGATGAACCGTTCCTGACCTGGCTTGAAGACAACGTCGACGCCCTGCGTGCGCTGGATCAAACGGCCCTGA
CCTATGCCATCGAGCGCTCCTGTGCCGCCAAGGCGGCGGTGGTCGGCGCCGACGAGAAGGAAACCGGCGTGCGCGCCACG
CTCAATCTCGGCCACACCTTTGGTCACGCCATCGAAACCCACATGGGCTATGGTGTCTGGTTGCATGGTGAAGCGGTCGC
CGCTGGCACCGTGATGGCGCTGGAAATGTCCGCGCGCCTGGGCTGGATCAGCGAGCAGGAGCGTGATCGCGGCATCCGCC
TGTTCCAGCGTGCCGGTCTGCCGGTGATCCCGCCGGAAGAGATGACCGAAGCCGATTTTCTTGAACACATGGCAATTGAC
AAAAAAGTGATCGACGGTCGCTTGCGCTTGGTGCTGCTGCGCCGGATGGGCGAAGCGGTGGTGACCGACGATTATCCGAA
AGAGGTTCTACAGGCCACGCTGGGAGCGGATTACCGCGCTCTGGCTCAGCTTAAAGGTTAA

Upstream 100 bases:

>100_bases
TGTGGCGGATGGCGAGCGAGCGGCGTCATACCCGCTATAGGCCGCAGACAACCAATAATTCAGGGCAGGACGCCTGCTTC
CATCTTCACTGTGGGGACAC

Downstream 100 bases:

>100_bases
TAAGATTCCGATGACTAGTTTGCATGCCGACGAGGCGTTCCTCGGCCATTTCCAGTTAAGTCACGACCCTTTCGCGCCGC
GGGTGCCGGGCTTCAAATTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQTLKVDLGERSYPIHIGEGLLDQPELLAPHIHGRQVAIISNETVAPLYLERLTRSLAQFSVVSVVLPDGEAFKNWETLQ
LIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPNV
VLIDTASLKTLPARELSAGLAEVIKYGLICDEPFLTWLEDNVDALRALDQTALTYAIERSCAAKAAVVGADEKETGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSARLGWISEQERDRGIRLFQRAGLPVIPPEEMTEADFLEHMAID
KKVIDGRLRLVLLRRMGEAVVTDDYPKEVLQATLGADYRALAQLKG

Sequences:

>Translated_366_residues
MQTLKVDLGERSYPIHIGEGLLDQPELLAPHIHGRQVAIISNETVAPLYLERLTRSLAQFSVVSVVLPDGEAFKNWETLQ
LIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPNV
VLIDTASLKTLPARELSAGLAEVIKYGLICDEPFLTWLEDNVDALRALDQTALTYAIERSCAAKAAVVGADEKETGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSARLGWISEQERDRGIRLFQRAGLPVIPPEEMTEADFLEHMAID
KKVIDGRLRLVLLRRMGEAVVTDDYPKEVLQATLGADYRALAQLKG
>Mature_366_residues
MQTLKVDLGERSYPIHIGEGLLDQPELLAPHIHGRQVAIISNETVAPLYLERLTRSLAQFSVVSVVLPDGEAFKNWETLQ
LIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPNV
VLIDTASLKTLPARELSAGLAEVIKYGLICDEPFLTWLEDNVDALRALDQTALTYAIERSCAAKAAVVGADEKETGVRAT
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSARLGWISEQERDRGIRLFQRAGLPVIPPEEMTEADFLEHMAID
KKVIDGRLRLVLLRRMGEAVVTDDYPKEVLQATLGADYRALAQLKG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=352, Percent_Identity=58.2386363636364, Blast_Score=392, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6320332, Length=369, Percent_Identity=35.7723577235772, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39833; Mature: 39833

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLKVDLGERSYPIHIGEGLLDQPELLAPHIHGRQVAIISNETVAPLYLERLTRSLAQF
CCEEEEECCCCCCCEEECCCCCCCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
SVVSVVLPDGEAFKNWETLQLIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGV
EEEEEEECCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
DFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPNVVLIDTASLKTLPARELSAGL
CEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCHHHHHHHH
AEVIKYGLICDEPFLTWLEDNVDALRALDQTALTYAIERSCAAKAAVVGADEKETGVRAT
HHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEE
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSARLGWISEQERDRGIRLFQRAGL
EECCHHHHHHHHHHCCCEEEEECCHHHHCEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCC
PVIPPEEMTEADFLEHMAIDKKVIDGRLRLVLLRRMGEAVVTDDYPKEVLQATLGADYRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCHHH
LAQLKG
HHHCCC
>Mature Secondary Structure
MQTLKVDLGERSYPIHIGEGLLDQPELLAPHIHGRQVAIISNETVAPLYLERLTRSLAQF
CCEEEEECCCCCCCEEECCCCCCCCHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
SVVSVVLPDGEAFKNWETLQLIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGV
EEEEEEECCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
DFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPNVVLIDTASLKTLPARELSAGL
CEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCEEEEECCCCCCCCHHHHHHHH
AEVIKYGLICDEPFLTWLEDNVDALRALDQTALTYAIERSCAAKAAVVGADEKETGVRAT
HHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEE
LNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSARLGWISEQERDRGIRLFQRAGL
EECCHHHHHHHHHHCCCEEEEECCHHHHCEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCC
PVIPPEEMTEADFLEHMAIDKKVIDGRLRLVLLRRMGEAVVTDDYPKEVLQATLGADYRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCHHH
LAQLKG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA