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The map label for this gene is aroK [H]

Identifier: 77456638

GI number: 77456638

Start: 466551

End: 467069

Strand: Direct

Name: aroK [H]

Synonym: Pfl01_0410

Alternate gene names: 77456638

Gene position: 466551-467069 (Clockwise)

Preceding gene: 77456637

Following gene: 77456639

Centisome position: 7.25

GC content: 63.39

Gene sequence:

>519_bases
GTGCGAAATTTGATTCTTGTAGGACCGATGGGGGCTGGAAAAAGCACCATCGGCCGATTACTGGCCAAAGAGCTGCGCCT
GCCGTTCAAGGATTCCGACAAGGAAATTGAACTGCGTACGGGCGCCAATATCCCGTGGATCTTCGACAAGGAAGGCGAGC
CCGGCTTTCGTGACCGTGAGCAAGCGATGATCGCCGAGCTGTGCGCGTTCGACGGCGTGGTGCTGGCGACCGGCGGCGGC
GCGGTGATGCGCGATGCCAACCGCAAGGCCCTGCACGAGGGCGGGCGGGTGGTGTATCTGCACGCCTCCGTCGAGCAGCA
GGTCGGACGCACCTCTCGCGACCGCAACCGGCCGTTGCTGCGCACCGCCAATCCGGAGAAAACTCTGCGCGACCTGCTGG
CGATCCGTGATCCGCTCTATCGGGAAATCGCCGATCTGGTGGTAGAAACCGACGAGCGGCCACCGCGCATGGTCGTGCTC
GATATTCTCGACCGCCTGGCGCAGCTTCCGCCCCGTTAA

Upstream 100 bases:

>100_bases
TTCCGGCGTGATGTGGTTTCGGAGAAAAAATCCGAGCTGCTGGTATTTCTCACTCCGCGTATCATGAATAACCAGGCGAT
TGCTGTGAGTCGTTGATTCT

Downstream 100 bases:

>100_bases
AGCATCGCTCGAAATGCGCTATCCTCGGCGTCCTGTTACAGCCCGCCGAGGTTGTGGCGGATGGCGAGCGAGCGGCGTCA
TACCCGCTATAGGCCGCAGA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDREQAMIAELCAFDGVVLATGGG
AVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLLRTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVL
DILDRLAQLPPR

Sequences:

>Translated_172_residues
MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDREQAMIAELCAFDGVVLATGGG
AVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLLRTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVL
DILDRLAQLPPR
>Mature_172_residues
MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDREQAMIAELCAFDGVVLATGGG
AVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLLRTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVL
DILDRLAQLPPR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=52.4096385542169, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1786587, Length=168, Percent_Identity=34.5238095238095, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19275; Mature: 19275

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDRE
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCHHH
QAMIAELCAFDGVVLATGGGAVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLL
HHHHHHHHHHCCEEEEECCCCEECCCCHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCE
RTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVLDILDRLAQLPPR
ECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRNLILVGPMGAGKSTIGRLLAKELRLPFKDSDKEIELRTGANIPWIFDKEGEPGFRDRE
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCHHH
QAMIAELCAFDGVVLATGGGAVMRDANRKALHEGGRVVYLHASVEQQVGRTSRDRNRPLL
HHHHHHHHHHCCEEEEECCCCEECCCCHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCE
RTANPEKTLRDLLAIRDPLYREIADLVVETDERPPRMVVLDILDRLAQLPPR
ECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA