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The map label for this gene is algQ [H]

Identifier: 255961262

GI number: 255961262

Start: 6150074

End: 6150559

Strand: Reverse

Name: algQ [H]

Synonym: Pfl01_5482

Alternate gene names: 255961262

Gene position: 6150559-6150074 (Counterclockwise)

Preceding gene: 77461704

Following gene: 77461701

Centisome position: 95.53

GC content: 56.38

Gene sequence:

>486_bases
ATGACCCACAAGGGAAGAGAGATCGCCATGCTCGAAAGTTGTCAGAATGCTCAGGAACGTTGGGGTGGAGTTCATCTGCT
GATCGACCGCTGGCTGCAGGAGCGTGAGGAATTGATCGCTGCCTATGACAGGCTGGGCGCCAAACCTCAGGCACTGTCCG
AGGATCGAAAGCCCTTGCAGGAATTCTGCGGCGTGCTGGTCGATTACGTCTCGGCCGGGCACTTCGAGATCTACGAACAG
CTGACGGGCGAGGCCAAGGCCTTCAACGACAAGCGCGGCCTGGAACTGGCCGAGACGATCTATCCACGGATCGATGTCAT
TACTGAAAAGCTGCTCGCGTTCAACGACCTTTGCGATGAAGGCAAATGCGTTGCCGAGAAGTTCAAGGAGTTGGGCGGTC
TGCTCCACGAACGCTTCGAACTGGAAGACTGCCTGATCGAAGTGTTGCATACCGCACACAAGGAAGAGGATTCGGTTCAG
GCCTGA

Upstream 100 bases:

>100_bases
CTGGCCCGCACGTGTCATTGGAATTGTGTTGCTCGATGACGCTCTGCCCGGCCGCCTCTCAAAGCAATATTCACAAGAAG
AGGCGCGGGTGTAGAGCAGC

Downstream 100 bases:

>100_bases
ATCGAACCTCGCAAGACACAAAAACGGTGCGCCCCAGGCGCACCGTTTTTTATTGGGCGATCAACTGGTCGCGCCGCGCA
ATTCCACTTCGAACACCAAC

Product: anti-RNA polymerase sigma 70 factor

Products: NA

Alternate protein names: Alginate regulatory protein AlgR2 [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTHKGREIAMLESCQNAQERWGGVHLLIDRWLQEREELIAAYDRLGAKPQALSEDRKPLQEFCGVLVDYVSAGHFEIYEQ
LTGEAKAFNDKRGLELAETIYPRIDVITEKLLAFNDLCDEGKCVAEKFKELGGLLHERFELEDCLIEVLHTAHKEEDSVQ
A

Sequences:

>Translated_161_residues
MTHKGREIAMLESCQNAQERWGGVHLLIDRWLQEREELIAAYDRLGAKPQALSEDRKPLQEFCGVLVDYVSAGHFEIYEQ
LTGEAKAFNDKRGLELAETIYPRIDVITEKLLAFNDLCDEGKCVAEKFKELGGLLHERFELEDCLIEVLHTAHKEEDSVQ
A
>Mature_160_residues
THKGREIAMLESCQNAQERWGGVHLLIDRWLQEREELIAAYDRLGAKPQALSEDRKPLQEFCGVLVDYVSAGHFEIYEQL
TGEAKAFNDKRGLELAETIYPRIDVITEKLLAFNDLCDEGKCVAEKFKELGGLLHERFELEDCLIEVLHTAHKEEDSVQA

Specific function: The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e., under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, h

COG id: COG3160

COG function: function code K; Regulator of sigma D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rsd/AlgQ family [H]

Homologues:

Organism=Escherichia coli, GI1790428, Length=148, Percent_Identity=36.4864864864865, Blast_Score=76, Evalue=8e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007448 [H]

Pfam domain/function: PF04353 Rsd_AlgQ [H]

EC number: NA

Molecular weight: Translated: 18417; Mature: 18286

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHKGREIAMLESCQNAQERWGGVHLLIDRWLQEREELIAAYDRLGAKPQALSEDRKPLQ
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EFCGVLVDYVSAGHFEIYEQLTGEAKAFNDKRGLELAETIYPRIDVITEKLLAFNDLCDE
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKCVAEKFKELGGLLHERFELEDCLIEVLHTAHKEEDSVQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
THKGREIAMLESCQNAQERWGGVHLLIDRWLQEREELIAAYDRLGAKPQALSEDRKPLQ
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EFCGVLVDYVSAGHFEIYEQLTGEAKAFNDKRGLELAETIYPRIDVITEKLLAFNDLCDE
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKCVAEKFKELGGLLHERFELEDCLIEVLHTAHKEEDSVQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2514124; 2110144; 10984043 [H]