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The map label for this gene is lnt [H]

Identifier: 75674217

GI number: 75674217

Start: 18113

End: 19720

Strand: Direct

Name: lnt [H]

Synonym: Nwi_0018

Alternate gene names: 75674217

Gene position: 18113-19720 (Clockwise)

Preceding gene: 75674216

Following gene: 75674218

Centisome position: 0.53

GC content: 64.49

Gene sequence:

>1608_bases
GTGAGCCTGAGCATCGCGGGCAGCGCCAGGACGGCGGGTGTTGCCGTCACGTTGTCATGGGGATGGAAGCGCGCCTTCGT
TGCGCTTGCCTCCGGCGCAGCCTCATCGCTTGCCATGGAGCCCTTCAACGCCTGGCCGTTGCTGTTCGTCACCTTTCCGG
TCGCAACCTGGCTGATCGACGGCTCCGCCGGCCGTCTGCGCGGCGTGCCGGCCGCAGCGCTTGCCGGCTGGCTGTTCGGA
TTCGGCTATTTCGTCCCCGGCCTCTACTGGATCGGCAACGCCTTCCTTGTTGATGCGCAGACCTTCGCATGGCTGATACC
GTTCGCCGTCCTTGGCCTGCCGGCCTATCTCGCGCTCTTTACGGCGCTCGGTTTCGCCCTCGCGCGCTTTATCTGGACCA
CGGACGCCTCGCGCATTCTCGCGCTCGCCGCCGCGCTGACGATCAGTGAATGGCTGCGCGGACACGTCCTGACAGGCTTC
CCGTGGAATGCATTCGGCTACGCGCTGACGGAGCCGCTGGCGCTGGCGCAAACCGCCTCGCTGATCGGATTGTGGGGCTT
GACGTTCATCGGCGTCGCCATCTTCGCGAGCCCCGCGGTGCTGATCGACGGCGGGAGCCGCGGCCGCAGACCGTGGCTCG
TCCCGGTCACCGCGCTCATGCTGCTCCTCGCCATGAGCATCTACGGTTCAGTCAGGCTATCGCGGCATCCGACGGAATTC
GCGGACAACGTGAAACTACGTATCATGCAGCCCAATCTGGCGCAGGACGCGCGGTTCAACTATTCCGCCAAGGCGGCGGT
GATGCAGAAGTACCTGGCGCTGTCGGACCGGGCCACCGGACCGCACTCAACGGGCGTCAGCGGCGCGACCATCCTGATCT
GGCCCGAATCGGCTTTCCCGTTTTTTCTGACCCGCGAAGCCGACGCGATGGCGGAAATCGCCGATCTCCTGCCGAAAGGC
ACGATCCTCATGACCGGCTCGGTGCGCGCTCCCGACCCGTCGCCGAACGGCAGGATCACCAGAGCTTTCAACTCGATCTA
TGTCATCGGCGATGACGGCGGCATCCTGTCGATCTACGACAAGCTCCATTTGGTGCCGTTTGGCGAATTCCTGCCGTTTC
AGGGACTGATGGAAAAGCTCGGCTTCGTTCAACTCACCAAGGTCCAGGGCGGTTTCATTCCCGGAAAGAGCCGGCGGACC
ATCGAGCTTCCGAACGCCCCGAGCGTTCTCCCGCTGATCTGCTACGAGGCGATCTTTCCGGACGGGATGCAGACCAGGGG
CGGTCGGCCGGGCTGGATCGTCAACCTCACCAATGACGGCTGGTTCGGCATCAGCACGGGGCCTCATCAGCATCTTCAGC
AGGCGCGGCTGCGCGCCATCGAGCAGGGACTGCCCCTCGTGCGAGCGGCGAACACCGGTATTTCCGTAGTTACGGATCCC
GTAGGGCGTATTGTCGCACGGCTCGATCTCGGCGTGGAAAGCGTTCTGGACTCTCGCTTGCCCGTCAACATGACGCCAAC
GCCCTACGCCCGCGCAGGTGATATTCCCGCCGCAATCATGGTGACCATGGCGCTCGTCCTGGTGATTCGCCGGCGTCGCG
GGCACTAG

Upstream 100 bases:

>100_bases
CGCGCGACGGCCGACGCCGGGAGAACGCGCCGGATGCAACCTCGCAATCGCAGGGCGATCCGGCCTCTCCTTCATCGCCG
GGCGACGGAGGCGACCCCCA

Downstream 100 bases:

>100_bases
CCGCGACGCGCACGTCATCTTGATCACCGGGTATCTTGATCACCGGGTACGATGTTCACGGCAGCGCTTCGTTCACACGA
TCGATATAATTCGTGTAACA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSLSIAGSARTAGVAVTLSWGWKRAFVALASGAASSLAMEPFNAWPLLFVTFPVATWLIDGSAGRLRGVPAAALAGWLFG
FGYFVPGLYWIGNAFLVDAQTFAWLIPFAVLGLPAYLALFTALGFALARFIWTTDASRILALAAALTISEWLRGHVLTGF
PWNAFGYALTEPLALAQTASLIGLWGLTFIGVAIFASPAVLIDGGSRGRRPWLVPVTALMLLLAMSIYGSVRLSRHPTEF
ADNVKLRIMQPNLAQDARFNYSAKAAVMQKYLALSDRATGPHSTGVSGATILIWPESAFPFFLTREADAMAEIADLLPKG
TILMTGSVRAPDPSPNGRITRAFNSIYVIGDDGGILSIYDKLHLVPFGEFLPFQGLMEKLGFVQLTKVQGGFIPGKSRRT
IELPNAPSVLPLICYEAIFPDGMQTRGGRPGWIVNLTNDGWFGISTGPHQHLQQARLRAIEQGLPLVRAANTGISVVTDP
VGRIVARLDLGVESVLDSRLPVNMTPTPYARAGDIPAAIMVTMALVLVIRRRRGH

Sequences:

>Translated_535_residues
MSLSIAGSARTAGVAVTLSWGWKRAFVALASGAASSLAMEPFNAWPLLFVTFPVATWLIDGSAGRLRGVPAAALAGWLFG
FGYFVPGLYWIGNAFLVDAQTFAWLIPFAVLGLPAYLALFTALGFALARFIWTTDASRILALAAALTISEWLRGHVLTGF
PWNAFGYALTEPLALAQTASLIGLWGLTFIGVAIFASPAVLIDGGSRGRRPWLVPVTALMLLLAMSIYGSVRLSRHPTEF
ADNVKLRIMQPNLAQDARFNYSAKAAVMQKYLALSDRATGPHSTGVSGATILIWPESAFPFFLTREADAMAEIADLLPKG
TILMTGSVRAPDPSPNGRITRAFNSIYVIGDDGGILSIYDKLHLVPFGEFLPFQGLMEKLGFVQLTKVQGGFIPGKSRRT
IELPNAPSVLPLICYEAIFPDGMQTRGGRPGWIVNLTNDGWFGISTGPHQHLQQARLRAIEQGLPLVRAANTGISVVTDP
VGRIVARLDLGVESVLDSRLPVNMTPTPYARAGDIPAAIMVTMALVLVIRRRRGH
>Mature_534_residues
SLSIAGSARTAGVAVTLSWGWKRAFVALASGAASSLAMEPFNAWPLLFVTFPVATWLIDGSAGRLRGVPAAALAGWLFGF
GYFVPGLYWIGNAFLVDAQTFAWLIPFAVLGLPAYLALFTALGFALARFIWTTDASRILALAAALTISEWLRGHVLTGFP
WNAFGYALTEPLALAQTASLIGLWGLTFIGVAIFASPAVLIDGGSRGRRPWLVPVTALMLLLAMSIYGSVRLSRHPTEFA
DNVKLRIMQPNLAQDARFNYSAKAAVMQKYLALSDRATGPHSTGVSGATILIWPESAFPFFLTREADAMAEIADLLPKGT
ILMTGSVRAPDPSPNGRITRAFNSIYVIGDDGGILSIYDKLHLVPFGEFLPFQGLMEKLGFVQLTKVQGGFIPGKSRRTI
ELPNAPSVLPLICYEAIFPDGMQTRGGRPGWIVNLTNDGWFGISTGPHQHLQQARLRAIEQGLPLVRAANTGISVVTDPV
GRIVARLDLGVESVLDSRLPVNMTPTPYARAGDIPAAIMVTMALVLVIRRRRGH

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=535, Percent_Identity=30.4672897196262, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57569; Mature: 57438

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSIAGSARTAGVAVTLSWGWKRAFVALASGAASSLAMEPFNAWPLLFVTFPVATWLID
CCEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
GSAGRLRGVPAAALAGWLFGFGYFVPGLYWIGNAFLVDAQTFAWLIPFAVLGLPAYLALF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
TALGFALARFIWTTDASRILALAAALTISEWLRGHVLTGFPWNAFGYALTEPLALAQTAS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCHHHHHHHHH
LIGLWGLTFIGVAIFASPAVLIDGGSRGRRPWLVPVTALMLLLAMSIYGSVRLSRHPTEF
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCEEECCCCHHH
ADNVKLRIMQPNLAQDARFNYSAKAAVMQKYLALSDRATGPHSTGVSGATILIWPESAFP
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
FFLTREADAMAEIADLLPKGTILMTGSVRAPDPSPNGRITRAFNSIYVIGDDGGILSIYD
EEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECEEEEEECCCCEEEEEC
KLHLVPFGEFLPFQGLMEKLGFVQLTKVQGGFIPGKSRRTIELPNAPSVLPLICYEAIFP
CEEEEECHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHCC
DGMQTRGGRPGWIVNLTNDGWFGISTGPHQHLQQARLRAIEQGLPLVRAANTGISVVTDP
CCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECH
VGRIVARLDLGVESVLDSRLPVNMTPTPYARAGDIPAAIMVTMALVLVIRRRRGH
HHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSIAGSARTAGVAVTLSWGWKRAFVALASGAASSLAMEPFNAWPLLFVTFPVATWLID
CEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
GSAGRLRGVPAAALAGWLFGFGYFVPGLYWIGNAFLVDAQTFAWLIPFAVLGLPAYLALF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
TALGFALARFIWTTDASRILALAAALTISEWLRGHVLTGFPWNAFGYALTEPLALAQTAS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCHHHHHHHHH
LIGLWGLTFIGVAIFASPAVLIDGGSRGRRPWLVPVTALMLLLAMSIYGSVRLSRHPTEF
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCEEECCCCHHH
ADNVKLRIMQPNLAQDARFNYSAKAAVMQKYLALSDRATGPHSTGVSGATILIWPESAFP
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
FFLTREADAMAEIADLLPKGTILMTGSVRAPDPSPNGRITRAFNSIYVIGDDGGILSIYD
EEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECEEEEEECCCCEEEEEC
KLHLVPFGEFLPFQGLMEKLGFVQLTKVQGGFIPGKSRRTIELPNAPSVLPLICYEAIFP
CEEEEECHHCCCHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHCC
DGMQTRGGRPGWIVNLTNDGWFGISTGPHQHLQQARLRAIEQGLPLVRAANTGISVVTDP
CCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECH
VGRIVARLDLGVESVLDSRLPVNMTPTPYARAGDIPAAIMVTMALVLVIRRRRGH
HHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA