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The map label for this gene is tlyC [H]

Identifier: 75674216

GI number: 75674216

Start: 16989

End: 18116

Strand: Direct

Name: tlyC [H]

Synonym: Nwi_0017

Alternate gene names: 75674216

Gene position: 16989-18116 (Clockwise)

Preceding gene: 75674215

Following gene: 75674217

Centisome position: 0.5

GC content: 67.29

Gene sequence:

>1128_bases
GTGCCTTCGGAGGACCAGACCAGCGAGAGCCCGCCGGCGCAGGAGAGCCGCAACCTGCCGGTGCCGGTGCACAATGGCGA
GGTTTTGCGCCCGGCCCCCGAGCGCTGGCTGATGCGCGCGATCCGCTCGCTGTTCGGATGGAAGGCGGGCTCCGTCCGGG
CTGACCTTCAGGTCGTGCTCGACGCCTCAACCCCGGACGAGACCAGCTTCACCGCGGTCGAGCGCACCATGCTGCGCAAT
ATCCTCAACCTGCACGAGCGACGCATCGCGGACGTCATGGTCCACCGCGCCGACATCGTCGCGGTCAAGCGCGATATTCC
GCTCGGCGAATTGATCAACCTGTTCGAAAGCGCGGCGCATTCCCGCCTCGTGGTCTATCACGAAAACCTCGACGATCCCG
AAGGCATGGTTCATATTCGCGACCTTCTCGCCTTCATGGCCCAGCGGGCGCGCACCGCGATGCCGTCCACGGCGAAACGC
AAAAAGAAGACGCCACCGGCCGGTCTCGACCTGCGGGCCATTGATCTGGCGCTGCCGCTGAGCGAGGCCGACATTACCCG
CAAGCTGCTCTACGTGCCACCGTCGATGCCGGCGATCGACCTGCTGGCGCAGATGCAGGCCTCCCGCATCCATCTGGCGC
TCGTCGTCGACGAATATGGCGGCACCGACGGGCTGGTGTCGATCGAGGACATCGTCGAGCAGGTCGTCGGCGAAATTGAT
GACGAGCACGATAGCGACGAGCCGCCATCGATCGTGCGCCAGACCGAGAACTCCTTCATTGCCGATGCCCGCGCCAGCCT
CGAGGACGTCCGCGCCATGATCGGCGAGGCGTTCGAGACCGGCGAAGCGGGCGAAGAGGTGGACACGCTCGGCGGCTTCC
TCGTCACCTATGTCGGTCGCCTGCCGGTGCGTGGCGAGGTCATTCTGGGGCCGGGACCGTTCGAGATCGAAGTGCTCGAC
GCTGATCCTCGCCGCGTCAAGCGACTGCGGATCGGCCTGCGCGCCGAGCGCCCCCCGGTCCGGCCGCGCGACGGCCGACG
CCGGGAGAACGCGCCGGATGCAACCTCGCAATCGCAGGGCGATCCGGCCTCTCCTTCATCGCCGGGCGACGGAGGCGACC
CCCAGTGA

Upstream 100 bases:

>100_bases
GACCGACGGGGAAGCCGAGGAAATGGAAAGTCTCGAACGTCAAATTCTGGCGCAGCTCGGAATCCCTGATCCCTATGCGC
CCCCGGAACGGATGACCTGA

Downstream 100 bases:

>100_bases
GCCTGAGCATCGCGGGCAGCGCCAGGACGGCGGGTGTTGCCGTCACGTTGTCATGGGGATGGAAGCGCGCCTTCGTTGCG
CTTGCCTCCGGCGCAGCCTC

Product: ctransporter-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPSEDQTSESPPAQESRNLPVPVHNGEVLRPAPERWLMRAIRSLFGWKAGSVRADLQVVLDASTPDETSFTAVERTMLRN
ILNLHERRIADVMVHRADIVAVKRDIPLGELINLFESAAHSRLVVYHENLDDPEGMVHIRDLLAFMAQRARTAMPSTAKR
KKKTPPAGLDLRAIDLALPLSEADITRKLLYVPPSMPAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQVVGEID
DEHDSDEPPSIVRQTENSFIADARASLEDVRAMIGEAFETGEAGEEVDTLGGFLVTYVGRLPVRGEVILGPGPFEIEVLD
ADPRRVKRLRIGLRAERPPVRPRDGRRRENAPDATSQSQGDPASPSSPGDGGDPQ

Sequences:

>Translated_375_residues
MPSEDQTSESPPAQESRNLPVPVHNGEVLRPAPERWLMRAIRSLFGWKAGSVRADLQVVLDASTPDETSFTAVERTMLRN
ILNLHERRIADVMVHRADIVAVKRDIPLGELINLFESAAHSRLVVYHENLDDPEGMVHIRDLLAFMAQRARTAMPSTAKR
KKKTPPAGLDLRAIDLALPLSEADITRKLLYVPPSMPAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQVVGEID
DEHDSDEPPSIVRQTENSFIADARASLEDVRAMIGEAFETGEAGEEVDTLGGFLVTYVGRLPVRGEVILGPGPFEIEVLD
ADPRRVKRLRIGLRAERPPVRPRDGRRRENAPDATSQSQGDPASPSSPGDGGDPQ
>Mature_374_residues
PSEDQTSESPPAQESRNLPVPVHNGEVLRPAPERWLMRAIRSLFGWKAGSVRADLQVVLDASTPDETSFTAVERTMLRNI
LNLHERRIADVMVHRADIVAVKRDIPLGELINLFESAAHSRLVVYHENLDDPEGMVHIRDLLAFMAQRARTAMPSTAKRK
KKTPPAGLDLRAIDLALPLSEADITRKLLYVPPSMPAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQVVGEIDD
EHDSDEPPSIVRQTENSFIADARASLEDVRAMIGEAFETGEAGEEVDTLGGFLVTYVGRLPVRGEVILGPGPFEIEVLDA
DPRRVKRLRIGLRAERPPVRPRDGRRRENAPDATSQSQGDPASPSSPGDGGDPQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=293, Percent_Identity=23.8907849829352, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786879, Length=264, Percent_Identity=32.1969696969697, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082033, Length=268, Percent_Identity=27.6119402985075, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693175, Length=320, Percent_Identity=24.375, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788119, Length=267, Percent_Identity=23.9700374531835, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 41183; Mature: 41052

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSEDQTSESPPAQESRNLPVPVHNGEVLRPAPERWLMRAIRSLFGWKAGSVRADLQVVL
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEE
DASTPDETSFTAVERTMLRNILNLHERRIADVMVHRADIVAVKRDIPLGELINLFESAAH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHC
SRLVVYHENLDDPEGMVHIRDLLAFMAQRARTAMPSTAKRKKKTPPAGLDLRAIDLALPL
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEECCC
SEADITRKLLYVPPSMPAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQVVGEID
CHHHHHHEEEECCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHCC
DEHDSDEPPSIVRQTENSFIADARASLEDVRAMIGEAFETGEAGEEVDTLGGFLVTYVGR
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LPVRGEVILGPGPFEIEVLDADPRRVKRLRIGLRAERPPVRPRDGRRRENAPDATSQSQG
CCCCCEEEECCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPASPSSPGDGGDPQ
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSEDQTSESPPAQESRNLPVPVHNGEVLRPAPERWLMRAIRSLFGWKAGSVRADLQVVL
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEE
DASTPDETSFTAVERTMLRNILNLHERRIADVMVHRADIVAVKRDIPLGELINLFESAAH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHC
SRLVVYHENLDDPEGMVHIRDLLAFMAQRARTAMPSTAKRKKKTPPAGLDLRAIDLALPL
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEECCC
SEADITRKLLYVPPSMPAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQVVGEID
CHHHHHHEEEECCCCCCHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHCC
DEHDSDEPPSIVRQTENSFIADARASLEDVRAMIGEAFETGEAGEEVDTLGGFLVTYVGR
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LPVRGEVILGPGPFEIEVLDADPRRVKRLRIGLRAERPPVRPRDGRRRENAPDATSQSQG
CCCCCEEEECCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPASPSSPGDGGDPQ
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA