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The map label for this gene is yyaJ [H]

Identifier: 73539537

GI number: 73539537

Start: 2543724

End: 2545172

Strand: Direct

Name: yyaJ [H]

Synonym: Reut_B5716

Alternate gene names: 73539537

Gene position: 2543724-2545172 (Clockwise)

Preceding gene: 73539536

Following gene: 73539538

Centisome position: 93.31

GC content: 61.56

Gene sequence:

>1449_bases
GTGAGTCACATCGACGGAACGAAGTCATTCTCAGACAGTAACTCCCGCTCCTCCCATCTGTTGGCGCGGTTCGACCGCTT
GCCAACCATGAGCACGCATTACGCCTGGGCGGCATTGCTGGCAATCAACTTGATGCTGGAGTATTACGACAACGCCATCT
TTTCGTACGCTGCGCCGACCATCAAGGCGCACACGGGCATGAGTACCGAGCAGATCGGGGTTATCAGCAGCGCCCTCTAC
GTGGGGATGGTGATTGGCGCGCTGGCCGGCGGTTGGCTCTCCGACAGGGTGGGGCGTCGTCCAGTGCTGGTGTGGGGCAC
GGTCATGTACTCGCTCGGCGTGATCGTGACGGCGTTCGTCCCAGGGTACGAGATGATCCTGACCTCCCGCTTCGTGACTG
GACTGGGCGTGCAGGCGGCCACGTCGGTGCTGCTCGTCTACGTCGCCGAGATGTTCCCACGCCATGCACGCGGACGTTTT
CTCTCGCTCGTGACGATGGGCTACACAGCCTCGGCAGTGATTGCGGCGGCATTGGCCATGTTTTACCTGCCTACGGGCGG
ACCGAACACCTGGCGGTACCTGTTCTTGGCCGGCGGCATCGGCTTGCTGATTGCGCCCCTCGTGTATTTTTATCTGCCGG
AGTCAGTGCGCTGGTGCGTCTCTCGCGGGAAGCTCGAGCACGCAGCGCAGATTGTCGCCAGCCTGGAAGCGCGCGCGTTG
CGCAAGGGGCCGCTCGACGACCCCAATCCGCTGGCAGCGCAAGGCGGCGCAGCGAATGCCACCTTGCGGGACCTGCTGCG
GAACAAGGGGGTCTTGCGCAACCTGATCGTTCTGTTTGTGTCCTATTTCGGGGTGTACCTGGCGTACTACACTTGGATCA
ACTGGAGCATCTACGCGCTGGTGTATGGTCTCAAATACCCCCAGAAGGACGCGTATTTCATCATGTTCATCTGGGTCGTG
GTCTACGGTGTAATGCCTTTCATTGCCATGCGACTGCTGGATCGGTGGGAACGCAAGAACACCATCCTCTGCATGTCGGT
GTTCTGCGCGCTCGCGTTGGTTGTGCTGGGCCTTTCAACCAGCTATTGGGCCGTGGCCGTTATCGGCGGGGCGCTCGCCA
TCTTCAGTGGCTTCGTACTCAACGCCTACTACACATATATCCCCGAGACAATGCCAACGCAGTTGCGTGCCTTGGGCAAT
GGCATCGTGATGTCGGGTGCGCGGGTCGGCGGCGTGGTGTCCGGCGTGATGGGCGCGGCGCTGGTCACTGCGGGTGGCCT
GAAGTACGTAACGTGGACCGCCGCCGCCATCTACATCGCCTTCGCCATCCCCGTGCTTATCTTCGGCCCGCGCACCACCA
ACCGTTCGCTGGAAGCAGTAGCCGACGAAGAATTGGGCCTTGGGACGTCATGCGACCCCACCAAGTCAGCCGCGCACGCT
GCCGCATGA

Upstream 100 bases:

>100_bases
ATGGGAGGAGGGCGGTTGTGTCCGCATTCCGTGTGGAGGTGGCCGCATCACTGAAGTACCGAAGACCAATAACGGCGACA
GCGCCAACCGGAGACACACC

Downstream 100 bases:

>100_bases
ATCAGCTTTCACCTGCCCTGCAGTAAGGAGTCTTCCATGTTGCCCGTTCAAGAAAATCGGTGGGTCTCCACGCATTGGGG
CACCTACAACGTCACCGTGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSHIDGTKSFSDSNSRSSHLLARFDRLPTMSTHYAWAALLAINLMLEYYDNAIFSYAAPTIKAHTGMSTEQIGVISSALY
VGMVIGALAGGWLSDRVGRRPVLVWGTVMYSLGVIVTAFVPGYEMILTSRFVTGLGVQAATSVLLVYVAEMFPRHARGRF
LSLVTMGYTASAVIAAALAMFYLPTGGPNTWRYLFLAGGIGLLIAPLVYFYLPESVRWCVSRGKLEHAAQIVASLEARAL
RKGPLDDPNPLAAQGGAANATLRDLLRNKGVLRNLIVLFVSYFGVYLAYYTWINWSIYALVYGLKYPQKDAYFIMFIWVV
VYGVMPFIAMRLLDRWERKNTILCMSVFCALALVVLGLSTSYWAVAVIGGALAIFSGFVLNAYYTYIPETMPTQLRALGN
GIVMSGARVGGVVSGVMGAALVTAGGLKYVTWTAAAIYIAFAIPVLIFGPRTTNRSLEAVADEELGLGTSCDPTKSAAHA
AA

Sequences:

>Translated_482_residues
MSHIDGTKSFSDSNSRSSHLLARFDRLPTMSTHYAWAALLAINLMLEYYDNAIFSYAAPTIKAHTGMSTEQIGVISSALY
VGMVIGALAGGWLSDRVGRRPVLVWGTVMYSLGVIVTAFVPGYEMILTSRFVTGLGVQAATSVLLVYVAEMFPRHARGRF
LSLVTMGYTASAVIAAALAMFYLPTGGPNTWRYLFLAGGIGLLIAPLVYFYLPESVRWCVSRGKLEHAAQIVASLEARAL
RKGPLDDPNPLAAQGGAANATLRDLLRNKGVLRNLIVLFVSYFGVYLAYYTWINWSIYALVYGLKYPQKDAYFIMFIWVV
VYGVMPFIAMRLLDRWERKNTILCMSVFCALALVVLGLSTSYWAVAVIGGALAIFSGFVLNAYYTYIPETMPTQLRALGN
GIVMSGARVGGVVSGVMGAALVTAGGLKYVTWTAAAIYIAFAIPVLIFGPRTTNRSLEAVADEELGLGTSCDPTKSAAHA
AA
>Mature_481_residues
SHIDGTKSFSDSNSRSSHLLARFDRLPTMSTHYAWAALLAINLMLEYYDNAIFSYAAPTIKAHTGMSTEQIGVISSALYV
GMVIGALAGGWLSDRVGRRPVLVWGTVMYSLGVIVTAFVPGYEMILTSRFVTGLGVQAATSVLLVYVAEMFPRHARGRFL
SLVTMGYTASAVIAAALAMFYLPTGGPNTWRYLFLAGGIGLLIAPLVYFYLPESVRWCVSRGKLEHAAQIVASLEARALR
KGPLDDPNPLAAQGGAANATLRDLLRNKGVLRNLIVLFVSYFGVYLAYYTWINWSIYALVYGLKYPQKDAYFIMFIWVVV
YGVMPFIAMRLLDRWERKNTILCMSVFCALALVVLGLSTSYWAVAVIGGALAIFSGFVLNAYYTYIPETMPTQLRALGNG
IVMSGARVGGVVSGVMGAALVTAGGLKYVTWTAAAIYIAFAIPVLIFGPRTTNRSLEAVADEELGLGTSCDPTKSAAHAA
A

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=465, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI166064021, Length=379, Percent_Identity=24.2744063324538, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI213021148, Length=498, Percent_Identity=24.6987951807229, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI203098995, Length=216, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI21553331, Length=330, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI7662270, Length=297, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI166197673, Length=405, Percent_Identity=23.7037037037037, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI296080721, Length=407, Percent_Identity=26.7813267813268, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI296080719, Length=406, Percent_Identity=26.3546798029557, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI24497499, Length=406, Percent_Identity=26.3546798029557, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI296080734, Length=407, Percent_Identity=26.7813267813268, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI73695465, Length=245, Percent_Identity=23.265306122449, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI216548223, Length=213, Percent_Identity=25.3521126760563, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI20070188, Length=390, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI24497476, Length=390, Percent_Identity=25.6410256410256, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI262399383, Length=257, Percent_Identity=22.568093385214, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI302148518, Length=355, Percent_Identity=23.0985915492958, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24497490, Length=358, Percent_Identity=23.1843575418994, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI8923870, Length=450, Percent_Identity=23.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI42542386, Length=449, Percent_Identity=21.6035634743875, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI148664184, Length=417, Percent_Identity=21.5827338129496, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24497480, Length=374, Percent_Identity=24.8663101604278, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI24497478, Length=374, Percent_Identity=24.8663101604278, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788074, Length=415, Percent_Identity=27.9518072289157, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788068, Length=452, Percent_Identity=26.5486725663717, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789312, Length=433, Percent_Identity=24.0184757505774, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082231, Length=186, Percent_Identity=27.9569892473118, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789207, Length=448, Percent_Identity=24.1071428571429, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786229, Length=448, Percent_Identity=22.3214285714286, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082159, Length=210, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790463, Length=259, Percent_Identity=24.7104247104247, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081723, Length=345, Percent_Identity=26.3768115942029, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082404, Length=180, Percent_Identity=23.8888888888889, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=428, Percent_Identity=24.7663551401869, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565978, Length=196, Percent_Identity=27.0408163265306, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17554160, Length=383, Percent_Identity=24.0208877284595, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996338, Length=480, Percent_Identity=23.9583333333333, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320063, Length=324, Percent_Identity=24.6913580246914, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320007, Length=191, Percent_Identity=27.7486910994764, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324469, Length=209, Percent_Identity=24.4019138755981, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320595, Length=159, Percent_Identity=28.3018867924528, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324417, Length=376, Percent_Identity=22.6063829787234, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320745, Length=234, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322242, Length=376, Percent_Identity=22.6063829787234, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=496, Percent_Identity=23.5887096774194, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24640196, Length=496, Percent_Identity=23.5887096774194, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24640200, Length=496, Percent_Identity=23.5887096774194, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28573097, Length=226, Percent_Identity=28.7610619469027, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221330907, Length=339, Percent_Identity=25.6637168141593, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24649618, Length=363, Percent_Identity=24.5179063360882, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922874, Length=436, Percent_Identity=22.7064220183486, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648211, Length=225, Percent_Identity=23.5555555555556, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356505, Length=266, Percent_Identity=24.0601503759398, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573099, Length=211, Percent_Identity=23.696682464455, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573101, Length=211, Percent_Identity=23.696682464455, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922616, Length=431, Percent_Identity=23.4338747099768, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652793, Length=440, Percent_Identity=23.4090909090909, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24658792, Length=425, Percent_Identity=21.1764705882353, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24652795, Length=402, Percent_Identity=23.8805970149254, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52183; Mature: 52052

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIDGTKSFSDSNSRSSHLLARFDRLPTMSTHYAWAALLAINLMLEYYDNAIFSYAAPT
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IKAHTGMSTEQIGVISSALYVGMVIGALAGGWLSDRVGRRPVLVWGTVMYSLGVIVTAFV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHC
PGYEMILTSRFVTGLGVQAATSVLLVYVAEMFPRHARGRFLSLVTMGYTASAVIAAALAM
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHCCHHHHHHHHHHHH
FYLPTGGPNTWRYLFLAGGIGLLIAPLVYFYLPESVRWCVSRGKLEHAAQIVASLEARAL
HHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
RKGPLDDPNPLAAQGGAANATLRDLLRNKGVLRNLIVLFVSYFGVYLAYYTWINWSIYAL
HCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYGLKYPQKDAYFIMFIWVVVYGVMPFIAMRLLDRWERKNTILCMSVFCALALVVLGLST
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SYWAVAVIGGALAIFSGFVLNAYYTYIPETMPTQLRALGNGIVMSGARVGGVVSGVMGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
LVTAGGLKYVTWTAAAIYIAFAIPVLIFGPRTTNRSLEAVADEELGLGTSCDPTKSAAHA
HHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCCCCCCHHCC
AA
CC
>Mature Secondary Structure 
SHIDGTKSFSDSNSRSSHLLARFDRLPTMSTHYAWAALLAINLMLEYYDNAIFSYAAPT
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]