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The map label for this gene is dmsA [H]

Identifier: 73539538

GI number: 73539538

Start: 2545209

End: 2547515

Strand: Direct

Name: dmsA [H]

Synonym: Reut_B5717

Alternate gene names: 73539538

Gene position: 2545209-2547515 (Clockwise)

Preceding gene: 73539537

Following gene: 73539539

Centisome position: 93.36

GC content: 57.26

Gene sequence:

>2307_bases
ATGTTGCCCGTTCAAGAAAATCGGTGGGTCTCCACGCATTGGGGCACCTACAACGTCACCGTGGACCAAGGCCGTGTGTC
CAACATTCGATCCTGGCCTGGCGACCCTGCTCCGGCCCCCATCTGGGAGCAGCTCGATGGATCTCACACCAAGTTGAGGG
TTGCCTCACCTGCCATACGAAAGTCGTTTCTCGACAAGCAGCATCGGGCAAGTGGTGAGGGCCGAGGGCGCGAGCCATTT
GTCGAGGTGGATTGGAATACCGCCCTTGATATGGCCGCCGGGCAGTTACAGCGAGTCTGCTCATCGTACGGTAACTCGGC
GATTTTCGGTGGCTCTTATGGATGGGCGAGCGCCGGGCGATTCAATCACGCGCAAAGCCAGATTCACCGCTTTCTGAACC
TTCTGGGCGGCTATACGCGGTCGGTCAATTCATATAGCTATGGCGCAGGGGAGGTGATCATTCCCCGAGTGGTGGGCTCC
ATGCATAGCTTGGCGGACAGGCACACCTCGCTGAAATCCATGGTTCGAAGTACTCGACTGTTGGTGGCGTTTGGGGGATT
GCCGGAAAAGAATGCTCAGATGAATTCCGGTGGCGTGACACGCCATCACTACCGCGACACACTCGGGCAACTCGCACAGG
CAGGAGTGCGCCTGGTATCTATCAGCCCGATCCAGGATGACACCAGCGCACCATGCGAATGGATTCCCATACGTCCGCAG
ACTGATGTAGCCCTCATGCTTGGCCTGGCCTATGTTCTGGAAGCCGAGAACCTGGTCAACCGCGCCTTCCTGGACCGCTA
CACGGTCGGATACGACCGCTTCCGGCATTACCTGTTGGGCGAGTCCGACGGTGTGCCAAAGACGCCGCAGTGGGCATCGT
CCATATGCCGCATTTCCGCACAGGGCATCACGCATCTCGCGCGTGATATGGCACAGCAACGGACCATGATCACCATGTCA
TGGTCGCTGCAGCGGGCCGAGAATGGCGAGCAACCGTATTGGATGACAGTGGCCCTTGCATCGATGATCGGCCAGATTGG
CCTGGATGGCGGCGGATTTGGGTTCGGCTATGCCGCCATCAACGGTATCGGGCTTGACTCTATCACGGTGAAGATCCCCG
CGCTGCCGCAGGGCAAGAACCATGTGGATTCGTTTATTCCCGTGGCGCGCATTTCGGACATGCTACTCAACAAGGGGCAA
TCCTACCGTTACAACGGCGAGACCCTGACCTATCCCGACATACGGCTCATCTATTGGGCCGGGGGCAACCCGTTTCATCA
CCATCAAGATCTGAACCGACTCCGAAAGGCATGGGCGGTGCCAGAAACCATCATCGTCAATGAGCCCTGGTGGACAGCAA
CCGCAAAGCACGCGGACATCGTGTTCCCTACGACAGTCGCTTACGAGCGAAACGATATCGCTGGCACCAGTACAGACCCT
TTCATTATCGCGTCCGCAGCACATGTGAAACCGCACGCCCACGCGCGTAATGATTATGAGGTTTTTTCCGAGCTCGCCGC
CCGACTTGGCTTTGTGAAGAAGTTCACGGAAGGAAAGAGCGAGGAGGATTGGCTGCGATCTTTCTATGCACGGATCAAAG
AGCAGGGCGACGAACAGGGCCTGAGCTTCCCGCACTTCGATGAATTCTGGGCGAAGGGAATGATTGAGGTTCCGACGAGA
GAATCCCACACCGTTTTCTCGGAGTTCATCCATGATCCGGTAGGACAGCCCTTGCAGACGCCGTCTGGTCGCATTGAGAT
CTTTTCACAGACCATTCACGACTTCGGGATCAAGGCCCAGCCCGGGCATCCGGTGTGGATCGAGCCCGAGGAGTGGCTGG
GGTCTCCTAAGGTGCTCGAGTTTCCTTTGCATCTACTCTCGAACCAGCCAGCATCCAAGCTGCACAGCCAATATGACCAT
GCGCCGCACAGCAGGAAATTGAAGATATCTGACAGGGAGCCAATACGCATTCACCCAATCGATGCAGCGAGCCGAAACAT
TGAACACGGAATGATCGTTCGCGTATTCAATGCGCGAGGCAGTTGTCTCGCGGGTGTGATGGCGTCTGATGACGTGATTC
CTGGGGTGGTGCAAATGGCCACAGGCGCTTGGCTGGACCTGGTCTTTGGCGATGGAGATGGTCCACCTTTGGATAAGCAT
GGCAACCCCAATGTATTGACGCGCGATGTTGGCACATCGGAAATCGCGCAGGGCAGCACAGCGAATTCATGCCTTGTCCA
GATCGAGCGCTATGCCGGGGTTCTACCGACGACAACCTGCTTCGAGCCACCGGAGATCGTCAGGTGA

Upstream 100 bases:

>100_bases
CGAAGAATTGGGCCTTGGGACGTCATGCGACCCCACCAAGTCAGCCGCGCACGCTGCCGCATGAATCAGCTTTCACCTGC
CCTGCAGTAAGGAGTCTTCC

Downstream 100 bases:

>100_bases
TCATTGCCGAGTCACCCTTTGGCGCCACGTTGAACAGCCACCCTTGGCAATGGCTGCATGGCCCAGGGCTGCGCGCTTGC
CATACTGACTTCCATTCGCG

Product: molybdopterin oxidoreductase:molydopterin dinucleotide-binding region

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MLPVQENRWVSTHWGTYNVTVDQGRVSNIRSWPGDPAPAPIWEQLDGSHTKLRVASPAIRKSFLDKQHRASGEGRGREPF
VEVDWNTALDMAAGQLQRVCSSYGNSAIFGGSYGWASAGRFNHAQSQIHRFLNLLGGYTRSVNSYSYGAGEVIIPRVVGS
MHSLADRHTSLKSMVRSTRLLVAFGGLPEKNAQMNSGGVTRHHYRDTLGQLAQAGVRLVSISPIQDDTSAPCEWIPIRPQ
TDVALMLGLAYVLEAENLVNRAFLDRYTVGYDRFRHYLLGESDGVPKTPQWASSICRISAQGITHLARDMAQQRTMITMS
WSLQRAENGEQPYWMTVALASMIGQIGLDGGGFGFGYAAINGIGLDSITVKIPALPQGKNHVDSFIPVARISDMLLNKGQ
SYRYNGETLTYPDIRLIYWAGGNPFHHHQDLNRLRKAWAVPETIIVNEPWWTATAKHADIVFPTTVAYERNDIAGTSTDP
FIIASAAHVKPHAHARNDYEVFSELAARLGFVKKFTEGKSEEDWLRSFYARIKEQGDEQGLSFPHFDEFWAKGMIEVPTR
ESHTVFSEFIHDPVGQPLQTPSGRIEIFSQTIHDFGIKAQPGHPVWIEPEEWLGSPKVLEFPLHLLSNQPASKLHSQYDH
APHSRKLKISDREPIRIHPIDAASRNIEHGMIVRVFNARGSCLAGVMASDDVIPGVVQMATGAWLDLVFGDGDGPPLDKH
GNPNVLTRDVGTSEIAQGSTANSCLVQIERYAGVLPTTTCFEPPEIVR

Sequences:

>Translated_768_residues
MLPVQENRWVSTHWGTYNVTVDQGRVSNIRSWPGDPAPAPIWEQLDGSHTKLRVASPAIRKSFLDKQHRASGEGRGREPF
VEVDWNTALDMAAGQLQRVCSSYGNSAIFGGSYGWASAGRFNHAQSQIHRFLNLLGGYTRSVNSYSYGAGEVIIPRVVGS
MHSLADRHTSLKSMVRSTRLLVAFGGLPEKNAQMNSGGVTRHHYRDTLGQLAQAGVRLVSISPIQDDTSAPCEWIPIRPQ
TDVALMLGLAYVLEAENLVNRAFLDRYTVGYDRFRHYLLGESDGVPKTPQWASSICRISAQGITHLARDMAQQRTMITMS
WSLQRAENGEQPYWMTVALASMIGQIGLDGGGFGFGYAAINGIGLDSITVKIPALPQGKNHVDSFIPVARISDMLLNKGQ
SYRYNGETLTYPDIRLIYWAGGNPFHHHQDLNRLRKAWAVPETIIVNEPWWTATAKHADIVFPTTVAYERNDIAGTSTDP
FIIASAAHVKPHAHARNDYEVFSELAARLGFVKKFTEGKSEEDWLRSFYARIKEQGDEQGLSFPHFDEFWAKGMIEVPTR
ESHTVFSEFIHDPVGQPLQTPSGRIEIFSQTIHDFGIKAQPGHPVWIEPEEWLGSPKVLEFPLHLLSNQPASKLHSQYDH
APHSRKLKISDREPIRIHPIDAASRNIEHGMIVRVFNARGSCLAGVMASDDVIPGVVQMATGAWLDLVFGDGDGPPLDKH
GNPNVLTRDVGTSEIAQGSTANSCLVQIERYAGVLPTTTCFEPPEIVR
>Mature_768_residues
MLPVQENRWVSTHWGTYNVTVDQGRVSNIRSWPGDPAPAPIWEQLDGSHTKLRVASPAIRKSFLDKQHRASGEGRGREPF
VEVDWNTALDMAAGQLQRVCSSYGNSAIFGGSYGWASAGRFNHAQSQIHRFLNLLGGYTRSVNSYSYGAGEVIIPRVVGS
MHSLADRHTSLKSMVRSTRLLVAFGGLPEKNAQMNSGGVTRHHYRDTLGQLAQAGVRLVSISPIQDDTSAPCEWIPIRPQ
TDVALMLGLAYVLEAENLVNRAFLDRYTVGYDRFRHYLLGESDGVPKTPQWASSICRISAQGITHLARDMAQQRTMITMS
WSLQRAENGEQPYWMTVALASMIGQIGLDGGGFGFGYAAINGIGLDSITVKIPALPQGKNHVDSFIPVARISDMLLNKGQ
SYRYNGETLTYPDIRLIYWAGGNPFHHHQDLNRLRKAWAVPETIIVNEPWWTATAKHADIVFPTTVAYERNDIAGTSTDP
FIIASAAHVKPHAHARNDYEVFSELAARLGFVKKFTEGKSEEDWLRSFYARIKEQGDEQGLSFPHFDEFWAKGMIEVPTR
ESHTVFSEFIHDPVGQPLQTPSGRIEIFSQTIHDFGIKAQPGHPVWIEPEEWLGSPKVLEFPLHLLSNQPASKLHSQYDH
APHSRKLKISDREPIRIHPIDAASRNIEHGMIVRVFNARGSCLAGVMASDDVIPGVVQMATGAWLDLVFGDGDGPPLDKH
GNPNVLTRDVGTSEIAQGSTANSCLVQIERYAGVLPTTTCFEPPEIVR

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=775, Percent_Identity=40, Blast_Score=550, Evalue=1e-157,
Organism=Escherichia coli, GI145693196, Length=773, Percent_Identity=39.974126778784, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1787231, Length=785, Percent_Identity=38.2165605095541, Blast_Score=490, Evalue=1e-139,
Organism=Escherichia coli, GI87081797, Length=746, Percent_Identity=32.0375335120643, Blast_Score=305, Evalue=9e-84,
Organism=Escherichia coli, GI1787870, Length=752, Percent_Identity=30.4521276595745, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI171474008, Length=714, Percent_Identity=30.3921568627451, Blast_Score=274, Evalue=2e-74,
Organism=Escherichia coli, GI3868721, Length=712, Percent_Identity=20.9269662921348, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 85144; Mature: 85144

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVQENRWVSTHWGTYNVTVDQGRVSNIRSWPGDPAPAPIWEQLDGSHTKLRVASPAIR
CCCCCCCCEEEEECCEEEEEECCCCCHHHCCCCCCCCCCCHHHHCCCCCCEEEECCHHHH
KSFLDKQHRASGEGRGREPFVEVDWNTALDMAAGQLQRVCSSYGNSAIFGGSYGWASAGR
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
FNHAQSQIHRFLNLLGGYTRSVNSYSYGAGEVIIPRVVGSMHSLADRHTSLKSMVRSTRL
CHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
LVAFGGLPEKNAQMNSGGVTRHHYRDTLGQLAQAGVRLVSISPIQDDTSAPCEWIPIRPQ
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEECCCC
TDVALMLGLAYVLEAENLVNRAFLDRYTVGYDRFRHYLLGESDGVPKTPQWASSICRISA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QGITHLARDMAQQRTMITMSWSLQRAENGEQPYWMTVALASMIGQIGLDGGGFGFGYAAI
HHHHHHHHHHHHHCEEEEEEEEHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCHHHHH
NGIGLDSITVKIPALPQGKNHVDSFIPVARISDMLLNKGQSYRYNGETLTYPDIRLIYWA
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCEEEEEEE
GGNPFHHHQDLNRLRKAWAVPETIIVNEPWWTATAKHADIVFPTTVAYERNDIAGTSTDP
CCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECEEEEEECCCCCCCCCCC
FIIASAAHVKPHAHARNDYEVFSELAARLGFVKKFTEGKSEEDWLRSFYARIKEQGDEQG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
LSFPHFDEFWAKGMIEVPTRESHTVFSEFIHDPVGQPLQTPSGRIEIFSQTIHDFGIKAQ
CCCCCHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
PGHPVWIEPEEWLGSPKVLEFPLHLLSNQPASKLHSQYDHAPHSRKLKISDREPIRIHPI
CCCCEEECHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEC
DAASRNIEHGMIVRVFNARGSCLAGVMASDDVIPGVVQMATGAWLDLVFGDGDGPPLDKH
CHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCC
GNPNVLTRDVGTSEIAQGSTANSCLVQIERYAGVLPTTTCFEPPEIVR
CCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MLPVQENRWVSTHWGTYNVTVDQGRVSNIRSWPGDPAPAPIWEQLDGSHTKLRVASPAIR
CCCCCCCCEEEEECCEEEEEECCCCCHHHCCCCCCCCCCCHHHHCCCCCCEEEECCHHHH
KSFLDKQHRASGEGRGREPFVEVDWNTALDMAAGQLQRVCSSYGNSAIFGGSYGWASAGR
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
FNHAQSQIHRFLNLLGGYTRSVNSYSYGAGEVIIPRVVGSMHSLADRHTSLKSMVRSTRL
CHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
LVAFGGLPEKNAQMNSGGVTRHHYRDTLGQLAQAGVRLVSISPIQDDTSAPCEWIPIRPQ
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEECCCC
TDVALMLGLAYVLEAENLVNRAFLDRYTVGYDRFRHYLLGESDGVPKTPQWASSICRISA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QGITHLARDMAQQRTMITMSWSLQRAENGEQPYWMTVALASMIGQIGLDGGGFGFGYAAI
HHHHHHHHHHHHHCEEEEEEEEHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCHHHHH
NGIGLDSITVKIPALPQGKNHVDSFIPVARISDMLLNKGQSYRYNGETLTYPDIRLIYWA
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCEEEEEEE
GGNPFHHHQDLNRLRKAWAVPETIIVNEPWWTATAKHADIVFPTTVAYERNDIAGTSTDP
CCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECEEEEEECCCCCCCCCCC
FIIASAAHVKPHAHARNDYEVFSELAARLGFVKKFTEGKSEEDWLRSFYARIKEQGDEQG
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
LSFPHFDEFWAKGMIEVPTRESHTVFSEFIHDPVGQPLQTPSGRIEIFSQTIHDFGIKAQ
CCCCCHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
PGHPVWIEPEEWLGSPKVLEFPLHLLSNQPASKLHSQYDHAPHSRKLKISDREPIRIHPI
CCCCEEECHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEC
DAASRNIEHGMIVRVFNARGSCLAGVMASDDVIPGVVQMATGAWLDLVFGDGDGPPLDKH
CHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCC
GNPNVLTRDVGTSEIAQGSTANSCLVQIERYAGVLPTTTCFEPPEIVR
CCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]