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The map label for this gene is motA [H]

Identifier: 73539428

GI number: 73539428

Start: 2425280

End: 2426143

Strand: Direct

Name: motA [H]

Synonym: Reut_B5606

Alternate gene names: 73539428

Gene position: 2425280-2426143 (Clockwise)

Preceding gene: 73539427

Following gene: 73539429

Centisome position: 88.96

GC content: 62.85

Gene sequence:

>864_bases
GTGCTAGTAGTTCTTGGCTATATCGTCGTGGTAGCGGCGGTGCTTGGCGGTTATGCCATGACCGGCGGCCACATGGGCGC
GCTGTATCAACCGGCGGAACTTGTGATCATCGGTGGCGCTGCCGCCGGTGCCTTCATCGCCACCAATACCACCAAGGCGC
TCAAGGCAACGCTCAAGGCGTTGCCGGGCCTGTTCAAGAGCTCCAAGTACAAAAAGGAGCTGTACCTCGACGTCATGTCG
CTGCTGTACGTGCTGCTGTCCAAGGCACGCCGCGAAGGCATCCTGTTCCTCGAAAAGGAAATCGCCGATCCCGCCGCGAG
CAGCGTGTTCAGCCAGTATCCGCGCATCCTGTCCGATCCGGTCGTGATGGAGTTCCTCACGGACTACCTGCGCATGATGG
TCAACGGCAACATGAACGCGTTCGAGATCGAGGCCCTGATGGACCACGAGATCGAAACCTTCCGCCACGAAGCCGAAATC
CCTGCCCATGCGCTGTCGCGCGTCGGCGACGCACTGCCGGCCTTCGGCATCGTCGCCGCGGTGATGGGCGTGGTGCATGC
ACTGGCTTCGGCCGACCTGCCGCCGGCCGAACTGGGCGCGCTGATCGCGCACGCGATGGTCGGTACGTTCCTGGGCATTC
TGCTGGCCTACGGCTTTGTCTCGCCGCTTGCCGCGCGCATCGAGCTGCAGGTGTCGGAGAACGTCAAGGTCTACGAATGC
ATCAAGGTGGTCCTGCTTGCCTCGCTCAACGGTTATGCGCCGCTGGTGGCGGTCGAGTTCGGCCGCAAGGTGCTGTACTC
CACGGTGCGGCCGTCGTTCCTCGAGCTGGACGACCACGTCCGCGAAGTCAAGAGCCTGAGCTGA

Upstream 100 bases:

>100_bases
CTGGCAAGCTGCGCAGCACTGGTGGACCGGATCATCCCTGTCCGCCCGTGCAACGGGCAATCGTGCGTGACTGACGCGCT
TTTTTGACGGGGATCCGATC

Downstream 100 bases:

>100_bases
TCCTGCCGAGCCACCGTCATGAGCAGCGCAAACGATATGCGTCCGATCATCGTCCGCAGGGCGAAGTCGCACGCCAAACC
GCACGGCAACCATAGCTGGA

Product: chemotaxis MotA protein

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLVVLGYIVVVAAVLGGYAMTGGHMGALYQPAELVIIGGAAAGAFIATNTTKALKATLKALPGLFKSSKYKKELYLDVMS
LLYVLLSKARREGILFLEKEIADPAASSVFSQYPRILSDPVVMEFLTDYLRMMVNGNMNAFEIEALMDHEIETFRHEAEI
PAHALSRVGDALPAFGIVAAVMGVVHALASADLPPAELGALIAHAMVGTFLGILLAYGFVSPLAARIELQVSENVKVYEC
IKVVLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLS

Sequences:

>Translated_287_residues
MLVVLGYIVVVAAVLGGYAMTGGHMGALYQPAELVIIGGAAAGAFIATNTTKALKATLKALPGLFKSSKYKKELYLDVMS
LLYVLLSKARREGILFLEKEIADPAASSVFSQYPRILSDPVVMEFLTDYLRMMVNGNMNAFEIEALMDHEIETFRHEAEI
PAHALSRVGDALPAFGIVAAVMGVVHALASADLPPAELGALIAHAMVGTFLGILLAYGFVSPLAARIELQVSENVKVYEC
IKVVLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLS
>Mature_287_residues
MLVVLGYIVVVAAVLGGYAMTGGHMGALYQPAELVIIGGAAAGAFIATNTTKALKATLKALPGLFKSSKYKKELYLDVMS
LLYVLLSKARREGILFLEKEIADPAASSVFSQYPRILSDPVVMEFLTDYLRMMVNGNMNAFEIEALMDHEIETFRHEAEI
PAHALSRVGDALPAFGIVAAVMGVVHALASADLPPAELGALIAHAMVGTFLGILLAYGFVSPLAARIELQVSENVKVYEC
IKVVLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLS

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=285, Percent_Identity=63.859649122807, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30858; Mature: 30858

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVLGYIVVVAAVLGGYAMTGGHMGALYQPAELVIIGGAAAGAFIATNTTKALKATLKA
CCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHH
LPGLFKSSKYKKELYLDVMSLLYVLLSKARREGILFLEKEIADPAASSVFSQYPRILSDP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCHHHHHHHHHHHHHHCCH
VVMEFLTDYLRMMVNGNMNAFEIEALMDHEIETFRHEAEIPAHALSRVGDALPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VMGVVHALASADLPPAELGALIAHAMVGTFLGILLAYGFVSPLAARIELQVSENVKVYEC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHH
IKVVLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVVLGYIVVVAAVLGGYAMTGGHMGALYQPAELVIIGGAAAGAFIATNTTKALKATLKA
CCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHH
LPGLFKSSKYKKELYLDVMSLLYVLLSKARREGILFLEKEIADPAASSVFSQYPRILSDP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCHHHHHHHHHHHHHHCCH
VVMEFLTDYLRMMVNGNMNAFEIEALMDHEIETFRHEAEIPAHALSRVGDALPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VMGVVHALASADLPPAELGALIAHAMVGTFLGILLAYGFVSPLAARIELQVSENVKVYEC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHH
IKVVLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]