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The map label for this gene is resD [H]

Identifier: 73539421

GI number: 73539421

Start: 2418342

End: 2418719

Strand: Direct

Name: resD [H]

Synonym: Reut_B5599

Alternate gene names: 73539421

Gene position: 2418342-2418719 (Clockwise)

Preceding gene: 73539420

Following gene: 73539422

Centisome position: 88.71

GC content: 66.93

Gene sequence:

>378_bases
ATGCCTGCCACGTCTGTTCCCAGCATCCTCGTCGTCGATGATTCGCCGTCCCTGCGCCGCATGATTGCCGCATGCCTGCG
TGCCGGTGGCTATGCAGTGACCGAGGCCGCCGATGGAGACCAGGCACAGGCGCTCGCGGCGCAAGCGAGCTTCGACATGC
TGCTGACCGACCAGGTCATGCCGGGCATGGACGGGCTGACGCTGATCCGCCATCTGCGCGCGACCGAACGCTATGCAGGC
ATTCCCATCCTGATGCTGACCACCGAAGCCGACGACCGCATCCGCGAGCAGGCCCGCGAGGCCGGGGCATCGGGTTTCCT
GCCGAAACCCTTCGATCCCGACCAGCTCATGGCCGCGGTGGCCGAGCTGGGCAACTGA

Upstream 100 bases:

>100_bases
ATTGCCTTGACGGCAATCCCCGCAGCCCGCGCCGGCCTGTCCGCCGCCGGTCGCGCCATGCCCCTGTCGGATCCAACCGC
CGTGCGTCCACGGAGCCACC

Downstream 100 bases:

>100_bases
ACGGCCATTCACGCAATCCCCCACTAACGAAGGGGTCGAATTGCCGTGCGTAGCCCTTCAGGCACTCGCCGCGCTGCCGT
AAATAACGGGGGGACAAAGT

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MPATSVPSILVVDDSPSLRRMIAACLRAGGYAVTEAADGDQAQALAAQASFDMLLTDQVMPGMDGLTLIRHLRATERYAG
IPILMLTTEADDRIREQAREAGASGFLPKPFDPDQLMAAVAELGN

Sequences:

>Translated_125_residues
MPATSVPSILVVDDSPSLRRMIAACLRAGGYAVTEAADGDQAQALAAQASFDMLLTDQVMPGMDGLTLIRHLRATERYAG
IPILMLTTEADDRIREQAREAGASGFLPKPFDPDQLMAAVAELGN
>Mature_124_residues
PATSVPSILVVDDSPSLRRMIAACLRAGGYAVTEAADGDQAQALAAQASFDMLLTDQVMPGMDGLTLIRHLRATERYAGI
PILMLTTEADDRIREQAREAGASGFLPKPFDPDQLMAAVAELGN

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=36.9747899159664, Blast_Score=83, Evalue=7e-18,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=35.3982300884956, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=33.6283185840708, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1788191, Length=105, Percent_Identity=38.0952380952381, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=38.7931034482759, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=34.8214285714286, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=111, Percent_Identity=30.6306306306306, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=35.7142857142857, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI87082012, Length=115, Percent_Identity=29.5652173913043, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1787375, Length=110, Percent_Identity=30.9090909090909, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=30.1724137931034, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13273; Mature: 13142

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATSVPSILVVDDSPSLRRMIAACLRAGGYAVTEAADGDQAQALAAQASFDMLLTDQVM
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PGMDGLTLIRHLRATERYAGIPILMLTTEADDRIREQAREAGASGFLPKPFDPDQLMAAV
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AELGN
HHHCC
>Mature Secondary Structure 
PATSVPSILVVDDSPSLRRMIAACLRAGGYAVTEAADGDQAQALAAQASFDMLLTDQVM
CCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
PGMDGLTLIRHLRATERYAGIPILMLTTEADDRIREQAREAGASGFLPKPFDPDQLMAAV
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AELGN
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]