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The map label for this gene is pepE [H]

Identifier: 73539362

GI number: 73539362

Start: 2342034

End: 2342789

Strand: Reverse

Name: pepE [H]

Synonym: Reut_B5540

Alternate gene names: 73539362

Gene position: 2342789-2342034 (Counterclockwise)

Preceding gene: 73539363

Following gene: 73539361

Centisome position: 85.94

GC content: 64.95

Gene sequence:

>756_bases
ATGACCCAACGCATCCTCCTGATGAGCAGCTCGCGCAAGGACAACCTTGGCTACCTCGAGCACGCCAGCGAACAGATCCA
CACATTGCTCAAGCGCGAGCCGCGCAAGGTGCTGTTCGTGCCGTTCGCGGGCGTGACGTTCAGCTTCGATACCTATGAAG
GCATGGTCAAGCCGGTGTTCGAGAAGCTGGGCTACGCGCTCGAATCGATCCACCACAACGACGATCCGCTGCGCGCGGTG
AACGAAGCCGATGCCATCGCCGTGGGCGGCGGCAACACGTTCGCGCTGCTCAAGCGCCTGTATGACGCGGGCATCGTCGA
TGCGATTCGCGCGAAGGTGCGTGCGGGCACGCCGTACGTGGGCTGGAGCGCCGGCAGCAACGTAGCATGCCCGACCATCC
GCACCACCAACGACATGCCGATCGTGCAGCCGCCGTCGCTGCGCGCGCTTGGCCTGGTGCCGTTCCAGATCAACCCGCAT
TTCATCAGCGGCAAGCCCGCTGGCCATAACGGCGAAAGCCGTGAAGAGCGCCTGGCCGAGTTCCTGCACATCAATGCGCC
GGAACAGGTGTTCGCGCTGCCGGAAGGCTCGGCGCTGTACAGCGACGGCACCCATGGCACGGTGCTCGGCGAGCGTCGTG
CGCTGTGGTTCCCGGCGGAAGGCAAGGTCGAGACCATTCGCGAAGGCGAGACCTTTCCGCTGTCTCGCATCACCGGCCCG
GCCGGGATGCAGGACTGGCCGGGCTTCGCTATCTAA

Upstream 100 bases:

>100_bases
GCACTACTTCAATACCCACGAGGAAATCGACCGCGTGGCCGCGCTGATCCGCGCCGCCATTGCCTGATCTCCGATCCGAA
TCCTTGAAGGAAACCCAGAC

Downstream 100 bases:

>100_bases
GCGCCCGCCCCGCTGACCCCGCCGGGTCGTCAAGGCCCGGCCAATACGTAGAAACAAATACCGACGCAGGCCGCGGTCAT
CCGCCACCTGCGCGGCCCCC

Product: peptidase E

Products: NA

Alternate protein names: Alpha-aspartyl dipeptidase; Asp-specific dipeptidase; Dipeptidase E [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTQRILLMSSSRKDNLGYLEHASEQIHTLLKREPRKVLFVPFAGVTFSFDTYEGMVKPVFEKLGYALESIHHNDDPLRAV
NEADAIAVGGGNTFALLKRLYDAGIVDAIRAKVRAGTPYVGWSAGSNVACPTIRTTNDMPIVQPPSLRALGLVPFQINPH
FISGKPAGHNGESREERLAEFLHINAPEQVFALPEGSALYSDGTHGTVLGERRALWFPAEGKVETIREGETFPLSRITGP
AGMQDWPGFAI

Sequences:

>Translated_251_residues
MTQRILLMSSSRKDNLGYLEHASEQIHTLLKREPRKVLFVPFAGVTFSFDTYEGMVKPVFEKLGYALESIHHNDDPLRAV
NEADAIAVGGGNTFALLKRLYDAGIVDAIRAKVRAGTPYVGWSAGSNVACPTIRTTNDMPIVQPPSLRALGLVPFQINPH
FISGKPAGHNGESREERLAEFLHINAPEQVFALPEGSALYSDGTHGTVLGERRALWFPAEGKVETIREGETFPLSRITGP
AGMQDWPGFAI
>Mature_250_residues
TQRILLMSSSRKDNLGYLEHASEQIHTLLKREPRKVLFVPFAGVTFSFDTYEGMVKPVFEKLGYALESIHHNDDPLRAVN
EADAIAVGGGNTFALLKRLYDAGIVDAIRAKVRAGTPYVGWSAGSNVACPTIRTTNDMPIVQPPSLRALGLVPFQINPHF
ISGKPAGHNGESREERLAEFLHINAPEQVFALPEGSALYSDGTHGTVLGERRALWFPAEGKVETIREGETFPLSRITGPA
GMQDWPGFAI

Specific function: Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids [H]

COG id: COG3340

COG function: function code E; Peptidase E

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S51 family [H]

Homologues:

Organism=Escherichia coli, GI1790452, Length=229, Percent_Identity=41.9213973799127, Blast_Score=181, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24641669, Length=225, Percent_Identity=44.4444444444444, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005320
- InterPro:   IPR023172 [H]

Pfam domain/function: PF03575 Peptidase_S51 [H]

EC number: =3.4.13.21 [H]

Molecular weight: Translated: 27480; Mature: 27348

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRILLMSSSRKDNLGYLEHASEQIHTLLKREPRKVLFVPFAGVTFSFDTYEGMVKPVF
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEHHHHHHHHHHH
EKLGYALESIHHNDDPLRAVNEADAIAVGGGNTFALLKRLYDAGIVDAIRAKVRAGTPYV
HHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEE
GWSAGSNVACPTIRTTNDMPIVQPPSLRALGLVPFQINPHFISGKPAGHNGESREERLAE
EECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCCCCCCHHHHHHHH
FLHINAPEQVFALPEGSALYSDGTHGTVLGERRALWFPAEGKVETIREGETFPLSRITGP
HHCCCCCHHEEECCCCCEEECCCCCCEEEECCCEEEECCCCCCCEECCCCCCCHHHCCCC
AGMQDWPGFAI
CCCCCCCCCCC
>Mature Secondary Structure 
TQRILLMSSSRKDNLGYLEHASEQIHTLLKREPRKVLFVPFAGVTFSFDTYEGMVKPVF
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEHHHHHHHHHHH
EKLGYALESIHHNDDPLRAVNEADAIAVGGGNTFALLKRLYDAGIVDAIRAKVRAGTPYV
HHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEE
GWSAGSNVACPTIRTTNDMPIVQPPSLRALGLVPFQINPHFISGKPAGHNGESREERLAE
EECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCEEECCCCCCCCCCHHHHHHHH
FLHINAPEQVFALPEGSALYSDGTHGTVLGERRALWFPAEGKVETIREGETFPLSRITGP
HHCCCCCHHEEECCCCCEEECCCCCCEEEECCCEEEECCCCCCCEECCCCCCCHHHCCCC
AGMQDWPGFAI
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA