Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 73539363

GI number: 73539363

Start: 2342823

End: 2344007

Strand: Reverse

Name: csd [H]

Synonym: Reut_B5541

Alternate gene names: 73539363

Gene position: 2344007-2342823 (Counterclockwise)

Preceding gene: 73539364

Following gene: 73539362

Centisome position: 85.98

GC content: 67.43

Gene sequence:

>1185_bases
ATGGATATCCAAGCGATCCGTGCCGGCACTCCGCTGACGGCCTCCACCATCTACCTCGACACGGCCGCGGCCTCGCTGCC
GCCCGACGTCGTGCTCGACACCGTGCGCAGCTACCTGCTCGACACCGGCCATGTGGGCATCTACCTGCCGGCGTTCCGCA
AGGAAACCTATGCACGGGTGGACGTCGTGCGCGGCAAGCTGGCCGCGCTGCTGAATGCCGCAGCCGACGAGATCGCCTTT
ACCAAGAACGCGACCGAAAGCATCTCTCTGGTCGCACGCGGCATCGCCTGGCAAGCCGGCGATGAAGTGCTGGTGGCCGA
CACCGAAATGCTCAGCAACCTGCTGCCGTGGCGCAGGCTCGAGCAAACCCACGGCATCGTGGTGAAGATGGTCGCCGCCA
ATGCCGAAGGCCTGCTGTCGCCCGACGCCTTCGCCGCCGCCATCACGCCGCGCACGCGCTTGCTGACGTTCTCGCATCTG
CCGAACTCGACGGGTGCGGTGCAGCCCGCGGCGCAGATCTGCGCCGTGGCGCGTCGGCATGGCGTGCTGTCGCTCGTCAA
TGCCGCGCAGAGCGTCGGCATGCTGCGCTCGGACGTGGCCGAACTCGATTGCGATTTCCTCGCCGGCTGCGGCCGCAAGG
CGCTGCGCGCGACCGAGGGCTCGGGCTTCCTGTATGTGCGCCGCGCGCTGATCGAGCACATCGAACCGTCCCTGGTCGGC
TGGTGGAACGGCGCCTATGACCGCGCGACCGGCGCGCTGTCGCTCGTCGCCGGCGCGCGCCGCTTCGAGGCGGGCTGCCC
GATCGTGCCGGCCATTCTCGGCATGGGTACCGCAATCGACTACGCAATGCAGATCGGCATCGACGCGATCGAAGCACGCG
TGCGCGACCTGACCGAGTACGCAGTGGCGAAGTTCTCGTCAATCCCGGGCTTCGAGCTGTACGGCCCGGCCGACGTATCG
AACCGCATCGGCATCGTGCCGTTCAACGTGCGCGGCGTGGACCCGGCCAGCATCGTCGCGGCGCTCGAAACGCAGCAATG
CATCATCGAAGCCGGTAATTTCATGGCGGACGCGATCCTGGCGCGCTATGGCGTGTCCACCATGGCGCGCGTGTCGCTGC
ACTACTTCAATACCCACGAGGAAATCGACCGCGTGGCCGCGCTGATCCGCGCCGCCATTGCCTGA

Upstream 100 bases:

>100_bases
GGCGACGCGCTGTTCAGTTTCTTCGGCTCTGTCACCAAGCTGCGCAAGTAACACGAGTCACGCAAGCCACACACCTTCCC
TGCATTACCAGAGACGTTCC

Downstream 100 bases:

>100_bases
TCTCCGATCCGAATCCTTGAAGGAAACCCAGACATGACCCAACGCATCCTCCTGATGAGCAGCTCGCGCAAGGACAACCT
TGGCTACCTCGAGCACGCCA

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDIQAIRAGTPLTASTIYLDTAAASLPPDVVLDTVRSYLLDTGHVGIYLPAFRKETYARVDVVRGKLAALLNAAADEIAF
TKNATESISLVARGIAWQAGDEVLVADTEMLSNLLPWRRLEQTHGIVVKMVAANAEGLLSPDAFAAAITPRTRLLTFSHL
PNSTGAVQPAAQICAVARRHGVLSLVNAAQSVGMLRSDVAELDCDFLAGCGRKALRATEGSGFLYVRRALIEHIEPSLVG
WWNGAYDRATGALSLVAGARRFEAGCPIVPAILGMGTAIDYAMQIGIDAIEARVRDLTEYAVAKFSSIPGFELYGPADVS
NRIGIVPFNVRGVDPASIVAALETQQCIIEAGNFMADAILARYGVSTMARVSLHYFNTHEEIDRVAALIRAAIA

Sequences:

>Translated_394_residues
MDIQAIRAGTPLTASTIYLDTAAASLPPDVVLDTVRSYLLDTGHVGIYLPAFRKETYARVDVVRGKLAALLNAAADEIAF
TKNATESISLVARGIAWQAGDEVLVADTEMLSNLLPWRRLEQTHGIVVKMVAANAEGLLSPDAFAAAITPRTRLLTFSHL
PNSTGAVQPAAQICAVARRHGVLSLVNAAQSVGMLRSDVAELDCDFLAGCGRKALRATEGSGFLYVRRALIEHIEPSLVG
WWNGAYDRATGALSLVAGARRFEAGCPIVPAILGMGTAIDYAMQIGIDAIEARVRDLTEYAVAKFSSIPGFELYGPADVS
NRIGIVPFNVRGVDPASIVAALETQQCIIEAGNFMADAILARYGVSTMARVSLHYFNTHEEIDRVAALIRAAIA
>Mature_394_residues
MDIQAIRAGTPLTASTIYLDTAAASLPPDVVLDTVRSYLLDTGHVGIYLPAFRKETYARVDVVRGKLAALLNAAADEIAF
TKNATESISLVARGIAWQAGDEVLVADTEMLSNLLPWRRLEQTHGIVVKMVAANAEGLLSPDAFAAAITPRTRLLTFSHL
PNSTGAVQPAAQICAVARRHGVLSLVNAAQSVGMLRSDVAELDCDFLAGCGRKALRATEGSGFLYVRRALIEHIEPSLVG
WWNGAYDRATGALSLVAGARRFEAGCPIVPAILGMGTAIDYAMQIGIDAIEARVRDLTEYAVAKFSSIPGFELYGPADVS
NRIGIVPFNVRGVDPASIVAALETQQCIIEAGNFMADAILARYGVSTMARVSLHYFNTHEEIDRVAALIRAAIA

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=305, Percent_Identity=26.5573770491803, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=30.9405940594059, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789175, Length=384, Percent_Identity=31.7708333333333, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI48994898, Length=400, Percent_Identity=29, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=279, Percent_Identity=29.3906810035842, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=398, Percent_Identity=25.6281407035176, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129463, Length=273, Percent_Identity=30.03663003663, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42005; Mature: 42005

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQAIRAGTPLTASTIYLDTAAASLPPDVVLDTVRSYLLDTGHVGIYLPAFRKETYARV
CCCCCCCCCCCCEEEEEEEECHHCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
DVVRGKLAALLNAAADEIAFTKNATESISLVARGIAWQAGDEVLVADTEMLSNLLPWRRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEECHHHHHHCCCHHHH
EQTHGIVVKMVAANAEGLLSPDAFAAAITPRTRLLTFSHLPNSTGAVQPAAQICAVARRH
HHHCCEEEEEEECCCCCCCCCCHHHEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
GVLSLVNAAQSVGMLRSDVAELDCDFLAGCGRKALRATEGSGFLYVRRALIEHIEPSLVG
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCEEE
WWNGAYDRATGALSLVAGARRFEAGCPIVPAILGMGTAIDYAMQIGIDAIEARVRDLTEY
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
AVAKFSSIPGFELYGPADVSNRIGIVPFNVRGVDPASIVAALETQQCIIEAGNFMADAIL
HHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
ARYGVSTMARVSLHYFNTHEEIDRVAALIRAAIA
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIQAIRAGTPLTASTIYLDTAAASLPPDVVLDTVRSYLLDTGHVGIYLPAFRKETYARV
CCCCCCCCCCCCEEEEEEEECHHCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
DVVRGKLAALLNAAADEIAFTKNATESISLVARGIAWQAGDEVLVADTEMLSNLLPWRRL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEECHHHHHHCCCHHHH
EQTHGIVVKMVAANAEGLLSPDAFAAAITPRTRLLTFSHLPNSTGAVQPAAQICAVARRH
HHHCCEEEEEEECCCCCCCCCCHHHEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
GVLSLVNAAQSVGMLRSDVAELDCDFLAGCGRKALRATEGSGFLYVRRALIEHIEPSLVG
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCEEE
WWNGAYDRATGALSLVAGARRFEAGCPIVPAILGMGTAIDYAMQIGIDAIEARVRDLTEY
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHH
AVAKFSSIPGFELYGPADVSNRIGIVPFNVRGVDPASIVAALETQQCIIEAGNFMADAIL
HHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
ARYGVSTMARVSLHYFNTHEEIDRVAALIRAAIA
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]